Protein Overview: h0004690

General Information:
Name(s) found:	h0004690 [Lars HPF FASTA]
Description(s) found:	[Lars HPF FASTA]
Organism:	SPECIES UNKNOWN
Length:	1303 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGPRGAAGG LAPEMRGAGA AGLLALLLLL LLLLLGLGGR VEGGPAGERG AGGGGALARE  60
   61 RFKVVFAPVI CKRTCLKGQC RDSCQQGSNM TLIGENGHST DTLTGSGFRV VVCPLPCMNG 120
  121 GQCSSRNQCL CPPDFTGRFC QVPAGGAGGG TGGSGPGLSR TGALSTGALP PLAPEGDSVA 180
  181 SKHAIYAVQV IADPPGPGEG PPAQHAAFLV PLGPGQISAE VQAPPPVVNV RVHHPPEASV 240
  241 QVHRIESSNA ESAAPSQHLL PHPKPSHPRP PTQKPLGRCF QDTLPKQPCG SNPLPGLTKQ 300
  301 EDCCGSIGTA WGQSKCHKCP QLQYTGVQKP GPVRGEVGAD CPQGYKRLNS THCQDINECA 360
  361 MPGVCRHGDC LNNPGSYRCV CPPGHSLGPS RTQCIADKPE EKSLCFRLVS PEHQCQHPLT 420
  421 TRLTRQLCCC SVGKAWGARC QRCPTDGTAA FKEICPAGKG YHILTSHQTL TIQGESDFSL 480
  481 FLHPDGPPKP QQLPESPSQA PPPEDTEEER GVTTDSPVSE ERSVQQSHPT ATTTPARPYP 540
  541 ELISRPSPPT MRWFLPDLPP SRSAVEIAPT QVTETDECRL NQNICGHGEC VPGPPDYSCH 600
  601 CNPGYRSHPQ HRYCVDVNEC EAEPCGPGRG ICMNTGGSYN CHCNRGYRLH VGAGGRSCVD 660
  661 LNECAKPHLC GDGGFCINFP GHYKCNCYPG YRLKASRPPV CEDIDECRDP SSCPDGKCEN 720
  721 KPGSFKCIAC QPGYRSQGGG ACRDVNECAE GSPCSPGWCE NLPGSFRCTC AQGYAPAPDG 780
  781 RSCLDVDECE AGDVCDNGIC SNTPGSFQCQ CLSGYHLSRD RSHCEDIDEC DFPAACIGGD 840
  841 CINTNGSYRC LCPQGHRLVG GRKCQDIDEC SQDPSLCLPH GACKNLQGSY VCVCDEGFTP 900
  901 TQDQHGCEEV EQPHHKKECY LNFDDTVFCD SVLATNVTQQ ECCCSLGAGW GDHCEIYPCP 960
  961 VYSSAEFHSL CPDGKGYTQD NNIVNYGIPA HRDIDECMLF GSEICKEGKC VNTQPGYECY1020
 1021 CKQGFYYDGN LLECVDVDEC LDESNCRNGV CENTRGGYRC ACTPPAEYSP AQRQCLSPEE1080
 1081 MDVDECQDPA ACRPGRCVNL PGSYRCECRP PWVPGPSGRD CQLPESPAER APERRDVCWS1140
 1141 QRGEDGMCAG PLAGPALTFD DCCCRQGRGW GAQCRPCPPR GAGSHCPTSQ SESNSFWDTS1200
 1201 PLLLGKPPRD EDSSEEDSDE CRCVSGRCVP RPGGAVCECP GGFQLDASRA RCVDIDECRE1260
 1261 LNQRGLLCKS ERCVNTSGSF RCVCKAGFAR SRPHGACVPQ RRR

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..395]	PSI-BLAST	15.69897	Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
2	View Details	[396..621]	FFAS03	3.08	Crystal structure of Methylated Pvs25, an ookinete protein from Plasmodium vivax
3	View Details	[622..734]	PSI-BLAST	5.0	Fibrillin-1
4	View Details	[735..823]	PSI-BLAST	3.69897	NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, MINIMIZED AVERAGE STRUCTURE
5	View Details	[824..1083]	FFAS03	4.29	Crystal structure of Methylated Pvs25, an ookinete protein from Plasmodium vivax
6	View Details	[1084..1303]	PSI-BLAST	5.522879	Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, holo form.

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
receptor binding	4.60755835611133	bayes_pls_golite062009
growth factor activity	4.38305031783896	bayes_pls_golite062009
extracellular matrix structural constituent	3.98005075037205	bayes_pls_golite062009
epidermal growth factor receptor binding	2.63546895705146	bayes_pls_golite062009
ErbB-2 class receptor binding	2.42443754640644	bayes_pls_golite062009
binding	2.33940742543305	bayes_pls_golite062009
protein binding	1.97546801934296	bayes_pls_golite062009
pattern binding	1.68711415550213	bayes_pls_golite062009
glycosaminoglycan binding	1.59362625477231	bayes_pls_golite062009
heparin binding	1.18377533277052	bayes_pls_golite062009
ErbB-3 class receptor binding	1.17748426017837	bayes_pls_golite062009
polysaccharide binding	0.907482471490999	bayes_pls_golite062009
transcription regulator activity	0.282532662545359	bayes_pls_golite062009
transcription factor binding	0.25804698792789	bayes_pls_golite062009
transcription cofactor activity	0.154111600670615	bayes_pls_golite062009

2

No functions predicted.

3

Term	Confidence	Notes
receptor binding	4.60755835611133	bayes_pls_golite062009
growth factor activity	4.38305031783896	bayes_pls_golite062009
extracellular matrix structural constituent	3.98005075037205	bayes_pls_golite062009
epidermal growth factor receptor binding	2.63546895705146	bayes_pls_golite062009
ErbB-2 class receptor binding	2.42443754640644	bayes_pls_golite062009
binding	2.33940742543305	bayes_pls_golite062009
protein binding	1.97546801934296	bayes_pls_golite062009
pattern binding	1.68711415550213	bayes_pls_golite062009
glycosaminoglycan binding	1.59362625477231	bayes_pls_golite062009
heparin binding	1.18377533277052	bayes_pls_golite062009
ErbB-3 class receptor binding	1.17748426017837	bayes_pls_golite062009
polysaccharide binding	0.907482471490999	bayes_pls_golite062009
transcription regulator activity	0.282532662545359	bayes_pls_golite062009
transcription factor binding	0.25804698792789	bayes_pls_golite062009
transcription cofactor activity	0.154111600670615	bayes_pls_golite062009

4

No functions predicted.

5

No functions predicted.

6

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

Philius confidence legend

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