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Protein Overview: AL1A2_RAT

General Information:
Name(s) found: AL1A2_RAT [Swiss-Prot]
Description(s) found:
Found 15 descriptions.
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  • Retinal dehydrogenase 2 OS=Rattus norvegicus GN=Aldh1a2 PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 518 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IEA]
    cytoplasm [UNKNOWN][IEA]
    cytosol [IDA]
    Biological Process: neural tube development [UNKNOWN][IEA]
    response to cytokine stimulus [UNKNOWN][IEA]
    midgut development [IEP]
    negative regulation of cell proliferation [UNKNOWN][IEA]
    positive regulation of cell proliferation [UNKNOWN][IEA]
    anterior/posterior pattern formation [UNKNOWN][IEA]
    retinoic acid metabolic process [UNKNOWN][IDA][TAS]
    retinal metabolic process [UNKNOWN][IEA]
    face development [UNKNOWN][IEA]
    determination of bilateral symmetry [UNKNOWN][IEA]
    proximal/distal pattern formation [UNKNOWN][IEA]
    embryonic limb morphogenesis [UNKNOWN]
    heart morphogenesis [UNKNOWN][IEA]
    retinoic acid receptor signaling pathway [UNKNOWN][IEA]
    forebrain development [UNKNOWN][IEA]
    blood vessel development [UNKNOWN][IEA]
    embryonic gut development [UNKNOWN][IEA]
    kidney development [IEP]
    hindbrain development [UNKNOWN][IEA]
    liver development [IEP]
    camera-type eye development [UNKNOWN]
    morphogenesis of embryonic epithelium [UNKNOWN][IEA]
    embryonic forelimb morphogenesis [UNKNOWN][IEA]
    lung development [UNKNOWN][IEA]
    pancreas development [UNKNOWN][IEA]
    neural crest cell development [UNKNOWN][IEA]
    neuron differentiation [UNKNOWN][IEA]
    embryonic camera-type eye development [UNKNOWN][IEA]
    9-cis-retinoic acid biosynthetic process [UNKNOWN][IEA]
    pituitary gland development [IEP]
    positive regulation of gene expression [UNKNOWN]
    positive regulation of apoptosis [UNKNOWN]
    response to estradiol stimulus [IEP]
    regulation of endothelial cell proliferation [UNKNOWN][IEA]
    oxidation reduction [IEA]
    response to vitamin A [IEP]
    Molecular Function: 3-chloroallyl aldehyde dehydrogenase activity [UNKNOWN][IEA]
    oxidoreductase activity [IEA]
    retinal dehydrogenase activity [UNKNOWN][IDA]
    retinal binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSSEIAMPG EVKADPAALM ASLQLLPSPT PNLEIKYTKI FINNEWQNSE SGRVFPVCNP  60
   61 ATGEQVCEVQ EADKVDIDKA VQAARLAFSL GSVWRRMDAS ERGRLLDKLA DLVERDRATL 120
  121 ATMESLNGGK PFLQAFYIDL QGVIKTLRYY AGWADKIHGM TIPVDGDYFT FTRHEPIGVC 180
  181 GQIIPWNFPL LMFTWKIAPA LCCGNTVVIK PAEQTPLSAL YMGALIKEAG FPPGVVNILP 240
  241 GYGPTAGAAI ASHIGIDKIA FTGSTEVGKL IQEAAGRSNL KRVTLELGGK SPNIIFADAD 300
  301 LDYAVEQAHQ GVFFNQGQCC TAGSRIFVEE SIYEEFVKRS VERAKRRIVG SPFDPTTEQG 360
  361 PQIDKKQYNK ILELIQSGVA EGAKLECGGK GLGRKGFFIE PTVFSNVTDD MRIAKEEIFG 420
  421 PVQEILRFKT MDEVIERANN SDFGLVAAVF TNDINKALMV SSAMQAGTVW INCYNALNAQ 480
  481 SPFGGFKMSG NGREMGEFGL REYSEVKTVT VKIPQKNS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle