Protein Overview: gi|80979085

General Information:
Name(s) found:	gi\|80979085 [NCBI NR]
Description(s) found: SHOW ONLY BEST	gi\|80979085\|gb\|ABB54745.1\| Dicer-2 [Drosophila melanogaster] [NCBI NR] Dicer-2 [Drosophila melanogaster] [nr-271106-contam.fasta] Dicer-2 (Fragment) OS=Drosophila melanogaster GN=Dcr-2 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
Organism:	Drosophila melanogaster
Length:	1715 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA]
Biological Process:	siRNA loading onto RISC involved in RNA interference [IMP] defense response to virus [IMP] chromatin silencing [IMP] production of siRNA involved in RNA interference [IDA][IMP][TAS] RNA interference [IDA][IMP][NAS][TAS] dsRNA transport [IMP] targeting of mRNA for destruction involved in RNA interference [IMP]
Molecular Function:	ATP binding [IEA] ribonuclease III activity [IEA] double-stranded RNA binding [IEA][ISS][NAS] ATP-dependent helicase activity [IEA] helicase activity [ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRGYQLRLVD HLTKSNGIVY LPTGSGKTFV AILVLKRFSQ DFDKPIESGG KRALFMCNTV  60
   61 ELARQQAMAV RRCTNFKVGF YVGEQGVDDW TRGMWSDEIK KNQVLVGTAQ VFLDMVTQTY 120
  121 VALSSLSVVI IDECHHGTGH HPFREFMRLF TIANQTKLPR VVGLTGVLIK GNEITNVATK 180
  181 LKELEITYRG NIITVSDTKE MENVMLYATK PTEVMVSFPH QEQVLTVTRL ISAEIEKFYV 240
  241 SLDLMNIGVQ PIRRSKSLQC LRDPSKKSFV KQLFNDFLYQ MKEYGIYAAS IAIISLIVEF 300
  301 DIKRRQAETL SVKLMHRTAL TLCEKIRHLL VQKLQDMTYD DDDDNVNTEE VIMNFSTPKV 360
  361 QRFLMSLKVS FADKDPKDIC CLVFVERRYT CKCIYGLLLN YIQSTPELRN VLTPQFMVGR 420
  421 NNISPDFESV LERKWQKSAI QQFRDGNANL MICSSVLEEG IDVQACNHVF ILDPVKTFNM 480
  481 YVQSKGRART TEAKFVLFTA DKEREKTIQQ IYQYRKAHND IAEYLKDRVL EKTEPELYEI 540
  541 KGHFQDDIDP FTNENGAVLL PNNALAILHR YCQTIPTDAF GFVIPWFHVL QEDERDRIFG 600
  601 VSAKGKHVIS INMPVNCMLR DTIYSDPMDN VKTAKISAAF KACKVLYSLG ELNERFVPKT 660
  661 LKERVAAIAD VHFEHWNKYG DSVTATVNKA DKSKDRTYKT ECPLEFYDAL PRVGEICYAY 720
  721 EIFLEPQFES CEYTEHMYLN LQTPRNYAIL LRNKLPRLAE MPLFSNQGKL HVRVANAPLE 780
  781 VIIQNSEQLE LLHQFHGMVF RDILKIWHPF FVLDRRSKEN SYLVVPLILG AGEQKCFDWE 840
  841 LMTNFRRLPQ SHGSNVQQRE QQPAPRPEDF EGKIVTQWYA NYDKRMLVTK VHRRLTPLSY 900
  901 MEKNQQDKTY YEFTMSKYGN RIGDVVHKDK FMIEVRDLTE QLTFYVHNRG KFNAKSKAKM 960
  961 KVILIPELCF NFNFPGDLWL KLIFLPSILN RMYFLLHAEA LRKRFNTYLN LHLLPFNGTD1020
 1021 YMPRPLEIDY SLKRNVDPLG NVIPTEDIEE PKSLLEPMPT KSIEASVANL EITEFENPWQ1080
 1081 KYMEPVDLSR NLLSTYPVEL DYYYHFSVGN VCEMNEMDFE DKEYWAKNQF HMPTGNIYGN1140
 1141 RTPAKTNANV PALMPSRPTV RGKVKPLLIL QKTVSKEHIT PAEQGEFLAA ITASSAADVF1200
 1201 DMERLEILGD SFLKLSATLY LASKYSDWNE GTLTEVKSKL VSNRNLLFCL IDADIPKTLN1260
 1261 TIQFTPRYTW LPPGISLPHN VLALWRENPE FAKMIGPHNL RDLALGDEES LVKGNCSDIN1320
 1321 YNRFVEGCRA NGQSFYAGAD FSSEVNFCVG LVTIPNKVIA DTLEALLGVI VKNYGLQHAF1380
 1381 KMLEYFKICR ADIDKPLTQL LNLELGGKKM RANVNTTEID GFLINHSYLE KNLGYTFKDR1440
 1441 RYLLQALTHP SYPTNRITGS YQELEFIGDA ILDFLISAYI FENNTKMNPG ALTDLRSALV1500
 1501 NNTTLACICV RHRLHFFILA ENAKLSEIIS KFVNFQESQG HRVTNYVRIL LEEADVQPTP1560
 1561 LDLDDELDMT ELPHANKCIS QEAEKGVPPK GEFNMSTNVD VPKALGDVLE ALIAAVYLDC1620
 1621 RDLQRTWEVI FNLFEPELQE FTRKVPINHI RQLVEHKHAK PVFSSPIVEG ETVMVSCQFT1680
 1681 CMEKTIKVYG FGSNKDQAKL SAAKHALQQL SKCDA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.90

Protein Overview: gi|80979085

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: