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Protein Overview: GNAS1_RAT

General Information:
Name(s) found: GNAS1_RAT [Swiss-Prot]
Description(s) found:
Found 7 descriptions.
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  • Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas OS=Rattus norvegicus GN=Gnas PE=1 SV=3 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 1144 amino acids

    Gene Ontology:
    Cellular Component: synaptic vesicle [IEA]
    synapse [IEA]
    extracellular region [IEA]
    intracellular part [IDA]
    plasma membrane [UNKNOWN][IDA]
    membrane fraction [UNKNOWN][IDA]
    endosome [IDA]
    heterotrimeric G-protein complex [IDA]
    cytoplasm [UNKNOWN][IDA]
    sarcolemma [IDA]
    ruffle [IEA]
    cell junction [IEA]
    cytoplasmic vesicle [IEA]
    vesicle [IDA]
    intrinsic to membrane [UNKNOWN]
    trans-Golgi network membrane [UNKNOWN]
    Biological Process: activation of adenylate cyclase activity by dopamine receptor signaling pathway [UNKNOWN]
    G-protein coupled receptor protein signaling pathway [IEA][IMP]
    signal transduction [IEA]
    post-embryonic body morphogenesis [UNKNOWN]
    post-embryonic development [UNKNOWN]
    energy reserve metabolic process [UNKNOWN]
    embryonic cranial skeleton morphogenesis [UNKNOWN]
    activation of adenylate cyclase activity by G-protein signaling pathway [UNKNOWN][IDA]
    positive regulation of osteoblast differentiation [UNKNOWN]
    hormone-mediated signaling pathway [UNKNOWN]
    skeletal system development [UNKNOWN]
    positive regulation of osteoclast differentiation [UNKNOWN]
    response to drug [UNKNOWN]
    endochondral ossification [UNKNOWN]
    embryonic hindlimb morphogenesis [UNKNOWN]
    cartilage development [UNKNOWN]
    Molecular Function: nucleotide binding [IEA]
    GTP binding [IEA][TAS]
    identical protein binding [UNKNOWN]
    protein binding [UNKNOWN]
    guanyl nucleotide binding [IEA]
    signal transducer activity [IDA][IEA]
    mu-type opioid receptor binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGMLNCLHGN NMSGQHDIPP EVGDQPEQEP LEAQGAAAPG AGVGPAEEME TEPSNNEPIP  60
   61 DETDSEVCGP PEDSKSDIQS PSQAFEEVQV GGDYSPPPEE AMPFEIQQPS LGDFWPTLEQ 120
  121 PGPSGTPSGI KAFNPAILEP GTPTGAHPGL GAYSPPPEEA MPFEFNEPAQ EDRCQPPLQV 180
  181 PDLAPGGPEA WVSRALPAEP GNLGFENTGF REDYSPPPEE SVPFQLDGEE FGGDSPPPGL 240
  241 PRVTPQIGIG GEFPTVAVPS TLCLAPAANA PPLWVQGAIG RPFREAVRSP NFAYDISPME 300
  301 ITRPLLEIGR ASTGVDDDTA VNMDSPPIAS DGPPIEVSGA PVKSEHAKRP PLERQAAETG 360
  361 NSPISSTTAE EAKVPSLERG EGSPTQPETV HIKPAPVAES GTDSSKADPD SATHAVLQIG 420
  421 PEEVGGVPTM PTDLPPASED AGPDVRAEPD GGTAPATPAE SEDNREPAAA AAAEPAAEPA 480
  481 AEPAAEPAAE PAAEPAAEAV PDTEAESASG AVPDTQEEPA AAAASATPAE PAARAAPVTP 540
  541 TEPATRAVPS ARAHPAAGAV PGASAMSAAA RAAAARAAYA GPLVWGARSL SATPAARASL 600
  601 PARAAAAARA ASAARAVAAG RSASAAPSRA HLRPPSPEIQ VADPPTPRPA PRPSAWPDKY 660
  661 ERGRSCCRYE AASGICEIES SSDESEEGAT GCFQWLLRRN RRPGQPRSHT VGSNPVRNFF 720
  721 ARAFGSCFGL SECTRSRSLS PGKAKDPMEE RRKQMRKEAM EMREQKRADK KRSKLIDKQL 780
  781 EEEKMDYMCT HRLLLLGAGE SGKSTIVKQM RILHVNGFNG EGGEEDPQAA RSNSDGEKAT 840
  841 KVQDIKNNLK EAIETIVAAM SNLVPPVELA NPENQFRVDY ILSVMNVPNF DFPPEFYEHA 900
  901 KALWEDEGVR ACYERSNEYQ LIDCAQYFLD KIDVIKQADY VPSDQDLPRC RVLTSGIFET 960
  961 KFQVDKVNFH MFDVGGQRDE RRKWIQCFND VTAIIFVVAS SSYNMVIRED NQTNRLQEAL1020
 1021 NLFKSIWNNR WLRTISVILF LNKQDLLAEK VLAGKSKIED YFPEFARYTT PEDATPEPGE1080
 1081 DPRVTRAKYF IRDEFLRIST ASGDGRHYCY PHFTCAVDTE NIRRVFNDCR DIIQRMHLRQ1140
 1141 YELL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle