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Protein Overview: gi|109497147, gi...

General Information:
Name(s) found: gi|62658830 [NCBI NR]
gi|109497147 [NCBI NR]
Description(s) found:
Found 4 descriptions.
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  • gi|62658830|ref|XP_341073.2| PREDICTED: similar to nuclear receptor co-repressor 2 [Rattus norvegicus] [NCBI NR]
  • gi|109497147|ref|XP_001074041.1| PREDICTED: similar to nuclear receptor co-repressor 2 [Rattus norvegicus] [NCBI NR]
    • Organism: Rattus norvegicus
    Length: 2468 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IDA]
    nuclear body [UNKNOWN]
    transcriptional repressor complex [UNKNOWN]
    histone deacetylase complex [UNKNOWN]
    [NOT]nucleolus [UNKNOWN]
    chromatin [IDA]
    cellular_component [ND]
    Biological Process: biological_process [ND]
    telencephalon development [UNKNOWN]
    cell proliferation in forebrain [UNKNOWN]
    negative regulation of fat cell differentiation [UNKNOWN]
    estrous cycle phase [IEP]
    regulation of transcription [IEA]
    negative regulation of transcription from RNA polymerase II promoter [UNKNOWN]
    white fat cell differentiation [UNKNOWN]
    heart morphogenesis [UNKNOWN]
    forebrain development [UNKNOWN]
    negative regulation of transcription, DNA-dependent [UNKNOWN]
    in utero embryonic development [UNKNOWN]
    negative regulation of transcription [UNKNOWN]
    glucose homeostasis [UNKNOWN]
    response to estradiol stimulus [IEP]
    response to organic nitrogen [IEP]
    negative regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN]
    Molecular Function: DNA binding [UNKNOWN][IEA]
    protein binding [UNKNOWN][IPI]
    histone deacetylase binding [UNKNOWN]
    transcription corepressor activity [UNKNOWN]
    protein N-terminus binding [UNKNOWN]
    Notch binding [UNKNOWN]
    sequence-specific DNA binding [UNKNOWN]
    chromatin binding [UNKNOWN]
    receptor activity [IEA]
    transcription repressor activity [UNKNOWN]
    molecular_function [ND]
    specific transcriptional repressor activity [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGSTQPVAQ TWRAAEPRYP PHGISYPVQI ARPHTDVGLL EYQHHPRDYT SHLSPGSIIQ  60
   61 PQRRRPSLLS EFQPGSERSQ ELHLRPESRT FLPELGKPDI EFTESKRPRL ELLPDTLLRP 120
  121 APLLATGQPS GSEDLTKDRS LAGKLEPVSP PSPPHADPEL ELTPSRLSKE ELIQNMDRVD 180
  181 REITMVEQQI SKLKKKQQQL EEEAAKPPEP EKPVSPPPIE SKHRSLVQII YDENRKKAEA 240
  241 AHRILEGLGP QVELPLYNQP SDTRQYHENI KINQAMRKKL ILYFKRRNHA RKQWEQRFCQ 300
  301 RYDQLMEAWE KKVERIENNP RRRAKESKVR EYYEKQFPEI RKQRELQERM QSRVGQRGSG 360
  361 LSMSAARSEH EVSEIIDGLS EQENLEKQMR QLAVIPPMLY DADQQRIKFI NMNGLMDDPM 420
  421 KVYKDRQVTN MWSEQERDTF REKFMQHPKN FGLIASFLER KTVAECVLYY YLTKKNENYK 480
  481 SLVRRSYRRR GKSQQQQQQQ QQQQQQQMAR SSQEEKEEKE KEKEADKEEE KQDAENEKEE 540
  541 LSKEKTDDTS GEDNDEKEAV ASKGRKTANS QGRRKGRITR SMANEANHEE TATPQQSSEL 600
  601 ASMEMNESSR WTEEEMETAK KGLLEHGRNW SAIARMVGSK TVSQCKNFYF NYKKRQNLDE 660
  661 ILQQHKLKME KERNARRKKK KTPAAASEET AFPPAAEDEE MEASGASANE EELAEEAEAS 720
  721 QASGNEVPRV GECSGPAAVN NSSDTESVPS PRTEATKDAG PKPASTEALP AATQPPVPPP 780
  781 EEPATVPDEP CPAPDASGPP SPVASPPPAA PPAAVDKDEQ DQAATVPQTE DAKEQKSEAE 840
  841 ELVIDVGKTE EPEAPEEPPE SVKSDHKEET EEEPEDKAKG PEAIETVSEA PLKVEEAGSK 900
  901 AAVTKGSSSG ATQDSDSSAT CSADEVDEPE GGDKGRLLSP RPSLLTPAGD PRASTSPQKP 960
  961 LDLKQLKQRA AAIPPIVTKV HEPPREDTVP PKPAPPVPPP TQHLQPEGDV SQQSGGSPRG1020
 1021 KCRSPVPPAE KEAEKASFFP AFPAEGPKLP TEPPRWTSGL PFPIPPREVI KTSPHAADPS1080
 1081 AFSYTPPGHP LPLGLHDSAR PVLPRPPISN PPPLISSAKH PGVLERQLGT ISQGMSVQLR1140
 1141 VPHSEHAKAP MGPLTMGLPL AVDPKKLGTA LGSTASGSIT KGLPSTRTAD GPSYRGSITH1200
 1201 GTPADVLYKG TISRIVGEDS PSRLDRARED TLPKGHVIYE GKKGHVLSYE GGMSVSQCSK1260
 1261 EDGRSSSGPP HETAAPKRTY DMMEGRVGRT ITSASIEGLM GRAIPEQHSP HLKEQHHIRG1320
 1321 SITQGIPRSY VEAQEDYLRR EAKLLKREGT PPPPPPPRDL TETYKTRPLD PLGPLKLKPT1380
 1381 HEGVVATVKE AGRSIHEIPR EELRRTPELP LAPRPLKEGS ITQGTPLKYD SGVPSSGSKK1440
 1441 HDVRSIIGSP GRPFPALHPL DIMADARALE RACYEESLKS RSGTSSGAGG SITRGAPVVV1500
 1501 PELGKPRQSP LAYEDHGAPF TSHLPRGSPV TTREPTPRLQ EGSLLSSKAS QDRKLTSTPR1560
 1561 EIAKSPHSTV PEHHPHPISP YEHLLRGVTG VDLYRGHIPL AFDPTSIPRG IPLEAAAAAY1620
 1621 YLPRHLAPSP TYPHLYPPYL IRGYPDTAAL ENRQTIINDY ITSQQMHHNA ASAMAQRADM1680
 1681 LRGLSPRESS LALNYAAGPR GIIDLSQVPH LPVLVPPTPG TPATAIDRLA YLPTAPPPFS1740
 1741 SRHSSSPLSP GGPTHLAKPT ATSSSERERE RERERDKSIL TSTTTVEHAP IWRPGTEQSS1800
 1801 GAGGSSRPAS HTHQHSPISP RTQDALQQRP SVLHNTSMKG VVTSVEPGTP TVLRSTSTSS1860
 1861 PVRPAATFPP ATHCPLGGTL EGVYPTLMEP VLLPKETSRV TRPERPRVDA GHAFLTKPPA1920
 1921 REPASSPSKS SEPRSLAPPS SSHTAIARTP AKSLAPHHAS PDLPAPTSAS DLHREKTQSK1980
 1981 PFSIQELELR SLGYHSGAGY SPDGVEPISP VSSPSLTHDK GLSKPLEELE KSHLEGELRH2040
 2041 KQPGPMKLSG EAAHLPHLRP LPESQPSSSP LLQTAPGIKG HQRVVTLAQH ISEVITQDYT2100
 2101 RHHPQQLSGP LPAPLYSFPG ASCPVLDLRR PPSDLYLPPP DHGTPARGSP HSEGGKRSPE2160
 2161 PSKTVLSSSE DAIEPVSPPE GMTEPGHARS TAYPLLYRDG EQGEPRMGSK SPGNTSQPPA2220
 2221 FFSKLTESNS AMVKSKKQEI NKKLNTHNRN EPEYNIGQPG TEIFNMPAIT GAGLMTCRSQ2280
 2281 AVQEHASTNM GLEAIIRKAL MGKYDQWEEP PPLGANAFNP LNASASLPAA AMPITTADGR2340
 2341 SDHPLTSPGG GGKAKVSGRP SSRKAKSPAP GLAPGDRPPS VSSVHSEGDC NRRTPLTNRV2400
 2401 WEDRPSSAGS TPFPYNPLIM RLQAGVMASP PPPGLAAGSG PLAGPHHAWD EEPKPLLCSQ2460
 2461 YETLSDSE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle