Protein Overview: M3K7_RAT

General Information:
Name(s) found:	M3K7_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|62648757\|ref\|XP_232855.3\| PREDICTED: similar to Mitogen-activated protein kinase kinase kinase 7 (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) [Rattus norvegicus] [NCBI NR] gi\|212276830\|sp\|P0C8E4.1\|M3K7_RAT RecName: Full=Mitogen-activated protein kinase kinase kinase 7 [NCBI NR] Mitogen-activated protein kinase kinase kinase 7 OS=Rattus norvegicus GN=Map3k7 PE=1 SV=1 [Swiss-Prot] Tax_Id=10116 PREDICTED: similar to Map3k7 protein [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] PREDICTED: similar to Mitogen-activated protein kinase kinase kinase 7 (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1) [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Map3k7 Mitogen-activated protein kinase kinase kinase 7 [rat-ipi-250309-contam.fasta] mitogen-activated protein kinase kinase kinase 7 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Mitogen-activated protein kinase kinase kinase 7 OS=Rattus norvegicus GN=Map3k7 [011711_HMR.fasta] Mitogen-activated protein kinase kinase kinase 7 OS=Rattus norvegicus GN=Map3k7 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	606 amino acids
Gene Ontology:
Cellular Component:	IkappaB kinase complex [UNKNOWN][IEA] cytosol [UNKNOWN] endosome membrane [UNKNOWN]
Biological Process:	positive regulation of JUN kinase activity [UNKNOWN][IEA] I-kappaB phosphorylation [UNKNOWN][IEA] signal transduction [IEA] activation of NF-kappaB-inducing kinase activity [UNKNOWN][IEA] transforming growth factor beta receptor signaling pathway [UNKNOWN][IEA] positive regulation of I-kappaB kinase/NF-kappaB cascade [UNKNOWN][IEA] protein amino acid phosphorylation [UNKNOWN][IDA][IEA] MAPKKK cascade [UNKNOWN] activation of MAPKK activity [IDA] neural tube formation [UNKNOWN][IEA] angiogenesis [UNKNOWN][IEA] negative regulation of apoptosis [UNKNOWN][IEA] positive regulation of JNK cascade [UNKNOWN][IEA] positive regulation of T cell cytokine production [UNKNOWN][IEA] positive regulation of interleukin-2 production [UNKNOWN][IEA]
Molecular Function:	nucleotide binding [IEA] magnesium ion binding [IEA] ATP binding [IDA][IEA] protein binding [UNKNOWN][IEA][IPI] MAP kinase kinase activity [UNKNOWN][IEA] protein kinase activity [UNKNOWN] MAP kinase kinase kinase activity [IDA][IEA] protein serine/threonine kinase activity [UNKNOWN][IEA] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTASAASSS SSSSASEMIE APSQVLNFEE IDYKEIEVEE VVGRGAFGVV CKAKWRAKDV  60
   61 AIKQIESESE RKAFIVELRQ LSRVNHPNIV KLYGACLNPV CLVMEYAEGG SLYNVLHGAE 120
  121 PLPYYTAAHA MSWCLQCSQG VAYLHSMQPK ALIHRDLKPP NLLLVAGGTV LKICDFGTAC 180
  181 DIQTHMTNNK GSAAWMAPEV FEGSNYSEKC DVFSWGIILW EVITRRKPFD EIGGPAFRIM 240
  241 WAVHNGTRPP LIKNLPKPIE SLMTRCWSKD PSQRPSMEEI VKIMTHLMRY FPGADEPLQY 300
  301 PCQYSDEGQS NSATSTGSFM DIASTNTSNK SDTNMEQVPA TNDTIKRLES KLLKNQAKQQ 360
  361 SDSGRLSLGA SRGSSVESLP PTSEGKRMSA DMSEIEARIV ATTAYTKPKR GHRKTASFGN 420
  421 ILDVPEIVIS GNGQPRRRSI QDLTVTGTEP GQVSSRSSSP SVRMITTSGP TSEKPARSLP 480
  481 WTPDDSTDTN GSDNSIPMAY LTLDHQLQPL APCPNSKESM AVFEQHCKMA QEYMKVQTEI 540
  541 ALLLQRKQEL VAELDQDEKD QQNTSRLVQE HKKLLDENKS LSTYYQQCKK QLEVIRSQQQ 600
  601 KRQGTS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: M3K7_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: