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Protein Overview: KAT6A_RAT

General Information:
Name(s) found: KAT6A_RAT [Swiss-Prot]
Description(s) found:
Found 15 descriptions.
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  • Histone acetyltransferase KAT6A OS=Rattus norvegicus GN=Kat6a PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 1998 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][ISS]
    MOZ/MORF histone acetyltransferase complex [UNKNOWN][ISS]
    nucleosome [IEA]
    Biological Process: chromatin modification [IEA]
    histone H3 acetylation [UNKNOWN][ISS]
    embryonic hemopoiesis [UNKNOWN][IEA]
    negative regulation of transcription [UNKNOWN][ISS]
    myeloid cell differentiation [UNKNOWN][ISS]
    somatic stem cell maintenance [UNKNOWN][IEA]
    positive regulation of transcription [UNKNOWN][ISS]
    histone acetylation [UNKNOWN][ISS]
    nucleosome assembly [IEA]
    Molecular Function: DNA binding [IEA]
    histone acetyltransferase activity [UNKNOWN][ISS]
    zinc ion binding [IEA]
    protein binding [UNKNOWN]
    acetyltransferase activity [UNKNOWN][ISS]
    metal ion binding [IEA]
    transcription factor binding [UNKNOWN][ISS]
    transcription activator activity [UNKNOWN][ISS]
    transferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKLANPLYT QWILEAIKKV KKQKQRPSEE RICNAVSSSH GLDRKTVLEQ LELSVKDGTI  60
   61 LKVSNKGLNS YKDPDNPGRI ALPKPRNHGK LDNKQSVDWN KLLKRAFEGL AESGGSTLKS 120
  121 IERFLKSQKD VSAACGGTAA SGFHQQLRLA IKRAVGHGRL LKDGPLYRLN TKAANAEGKE 180
  181 GCESLSCLPP VSLLPHEKDK PVAEPIPICS FCLGTKEQNR EKKPEDLISC ADCGNSGHPS 240
  241 CLKFSPELTV RVRALRWQCI ECKTCSSCRD QGKNADNMLF CDSCDRGFHM ECCDPPLTRM 300
  301 PKGMWICQIC RPRKKGRKLL QKKAAQIKRR YANPIGRPKN RLKKQSTVSK GPFSKVRTGP 360
  361 GRGRKRKITV SSQSASSSEE GYLERIDGLD FCRDSSAPLK FNKKTKGLID GLTKFFTPSP 420
  421 DGRKARGEAV DYSELRIRKK GNRKSSTSHW PTDNQDGWES KQESEERLFG SQEIMTERDM 480
  481 ELFRDIQEQA LQKVGVTGPP DPQVRCPSVI EFGKYEIHTW YSSPYPQEYS RLPKLYLCEF 540
  541 CLKYMKSRTI LQQHMKKCGW FHPPANEIYR KNNISVFEVD GNVSTIYCQN LCLLAKLFLD 600
  601 HKTLYYDVEP FLFYVLTQND VKGCHLVGYF SKEKHCQQKY NVSCIMILPQ YQRKGYGRFL 660
  661 IDFSYLLSKR EGQAGSPEKP LSDLGRLSYM AYWKSVILEC LYHQNDKQIS IKKLSKLTGV 720
  721 CPQDITSTLH HLRMLDFRSD QFVIIRREKL IQDHMAKLQL NLRPVDVDPE CLRWTPVIVS 780
  781 NSVVSEEEDE EADDGEKEEP QGQERELETR ERVGKSVSRE NKDQDSSSLI ESEKKPEVKE 840
  841 LASSSRLSKQ ALVRDSLPAN SQPPRRGRCG RKNRKTQERF GDKDSKMLVG ETLSTSQEQY 900
  901 GECEEKSAAS RERYTEVGEQ PAAPQAQADG NPDIPKGRFS ESADLWRGQL KKSPETLKCR 960
  961 LPEGNDRLPC CYTDGDRAVF RGFSESSEEE EEPESPRSNS PPVLTKPTLK RKKPILHRRR1020
 1021 RVRKRKHHNS SVVTETISET TEVLDEPFED SDSERPMPRL EPTFEIEEEE EEEDENELFP1080
 1081 RGYFHCLSSQ DILRCQASSK RTASKDEEEE EEESDDADDT PVLKPVSLLR KCDVNSASLE1140
 1141 PDTSTPMKKK KGWPKGKSRK PIHWKKRPGR KPGFKLNQDI IAVSTQECIV EPIVPIKPGR1200
 1201 KPRTQESEEL VEVKEGLVEE RKEEMHTEAD EEAEEEEDAA SSDIRAMSPL DSSNSPDADP1260
 1261 KEPEAEEEEE KPLDDPRQSE EEPQELEEQE QEEEDEVTAE ANQNEDHDAD DEDDGHLDSL1320
 1321 KTKEPEGQPA REDGTEEPGT QESFLDASIQ DSRENAKDKD ETEADSEEEQ PSHEASVGSE1380
 1381 TMPGSEEDHE EDSNTKEELI ELKEEEEIPH SELDLETVQA VQSLTQEESS EHEGAYQDCE1440
 1441 ETLAACQTLQ SYTHTDEDPQ MSMVEDCHAS EHNSPISSIP SHPSQSVRSV SSPSMPALES1500
 1501 GYTQISPEQG SLSAPSMQNM ETSPMMDVPS VSDHSQQVVD SGFSDLGSIE STTENYENPS1560
 1561 SYDSTMGSSI CGNNSSQSSC SYGGLSSSSS LTQNSCVVTQ QMASMGNSCS MLQQNSVQPA1620
 1621 TNCNIKSPQT CVVERPPSNQ QPPPPPPPPP PPQQPQPQPQ QQAAPQPPPP QPQQQPPPPP1680
 1681 QQQPQPPPPP QQQPPLSQCS MNNSFTAAPM IMEIPESGGT GNISIYERIP GDFGAGSYSQ1740
 1741 PSATFSLAKL QQLTNTIMDP HAMPYSHSPA VTSYATSVSL SNTGLAQLAP SHPLAGTPQA1800
 1801 QATMTPPPNL APTTMNLTSP LLQCNMSATN IGIPHTQRLQ GQMPVKGHIS IRSKSAPLPS1860
 1861 ATAHQQQLYG RSPPAVAMQA GPRALAVQRG MNMGVNLMPT PAYNVNSMNM NTLNAMNSYR1920
 1921 MTQPMMNSSY HSNPAYMNQT AQYPMQMQMG MMGSQAYTQQ PMQPNPHGNM MYTGPSHHSY1980
 1981 MNAAGVPKQS LNGPYMRR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle