Protein Overview: HCN2_RAT

General Information:
Name(s) found:	HCN2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|83303515\|sp\|Q9JKA9.3\|HCN2_RAT RecName: Full=Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [NCBI NR] Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 OS=Rattus norvegicus GN=Hcn2 PE=1 SV=3 [Swiss-Prot] Tax_Id=10116 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Hcn2 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [rat-ipi-250309-contam.fasta] Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 OS=Rattus norvegicus GN=Hcn2 [011711_HMR.fasta] Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 OS=Rattus norvegicus GN=Hcn2 PE=2 SV=3 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	863 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] dendritic shaft [IDA] integral to membrane [IEA] neuronal cell body [IDA] synapse [IDA] plasma membrane [IDA] axon [IDA]
Biological Process:	potassium ion transport [IEA] sodium ion transport [IEA] ion transport [IEA] regulation of membrane potential [UNKNOWN][IEA] transmembrane transport [IEA] response to drug [IEP] brain development [IEP] aging [IEP] response to hormone stimulus [IEP] positive regulation of heart contraction [IMP]
Molecular Function:	nucleotide binding [IEA] voltage-gated potassium channel activity [IEA] protein complex scaffold [IDA] protein binding [UNKNOWN][IPI] sodium channel activity [IEA] PDZ domain binding [IPI] voltage-gated ion channel activity [IEA] cAMP binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDARGGGGRP GDSPGTTPAP GPPPPPPPPA PLQLQPPPAP PPNPTTPSHP ESADEPGPRS  60
   61 RLCSRDSSCT PGAAKGGANG ECGRGEPQCS PEGPARGPKV SFSCRGAASG PAAAEEAGSE 120
  121 EAGPAGEPRG SQASFLQRQF GALLQPGVNK FSLRMFGSQK AVEREQERVK SAGAWIIHPY 180
  181 SDFRFYWDFT MLLFMVGNLI IIPVGITFFK DETTAPWIVF NVVSDTFFLM DLVLNFRTGI 240
  241 VIEDNTEIIL DPEKIKKKYL RTWFVVDFVS SIPVDYIFLI VEKGIDSEVY KTARALRIVR 300
  301 FTKILSLLRL LRLSRLIRYI HQWEEIFHMT YDLASAVMRI CNLISMMLLL CHWDGCLQFL 360
  361 VPMLQDFPSD CWVSINNMVN HSWSELYSFA LFKAMSHMLC IGYGRQAPES MTDIWLTMLS 420
  421 MIVGATCYAM FIGHATALIQ SLDSSRRQYQ EKYKQVEQYM SFHKLPADFR QKIHDYYEHR 480
  481 YQGKMFDEDS ILGELNGPLR EEIVNFNCRK LVASMPLFAN ADPNFVTAML TKLKFEVFQP 540
  541 GDYIIREGTI GKKMYFIQHG VVSVLTKGNK EMKLSDGSYF GEICLLTRGR RTASVRADTY 600
  601 CRLYSLSVDN FNEVLEEYPM MRRAFETVAI DRLDRIGKKN SILLHKVQHD LSSGVFNNQE 660
  661 NAIIQEIVKY DREMVQQAEL GQRVGFFPPP PPRQVRSAIA TLQQAVAMSF CPQVARPLVG 720
  721 PLALGSPRLV RRAPPGPLPP AASPGPPAAS PPAAPSSPRA PRTSPYGVPG SPATRVGPAL 780
  781 PARRLSRASR PLSASQPSLP HGAPAPSPAA SARPASSSTP RLGPAPTTRT AAPSPDRRDS 840
  841 ASPGAASGLD PLDSARSRLS SNL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: HCN2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: