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Protein Overview: ceh-8

General Information:
Name(s) found: ceh-8 / CE38130 [WormBase]
Description(s) found:
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  • WBGene00000433 locus:ceh-8 Homeobox protein ceh-8 status:Partially_confirmed UniProt:Q94398 protein_id:CAB03519.2 [WormBase]
  • gi|71997306|ref|NP_492246.2| Homeobox family member (ceh-8) [Caenorhabditis elegans] [NCBI NR]
  • gi|68056712|sp|Q94398.3|HM08_CAEEL RecName: Full=Homeobox protein ceh-8 [NCBI NR]
  • gi|60222935|emb|CAB03519.2| C. elegans protein ZK265.4, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • Homeobox protein ceh-8 OS=Caenorhabditis elegans GN=ceh-8 PE=3 SV=3 [Swiss-Prot]
  • CE38130 WBGene00000433 locus:ceh-8 homeobox protein (otd subfamily) status:Partially_confirmed SW:Q94398 protein_id:CAB03519.2 [wormpep150.fasta]
  • 38130 WBGene00000433 locus:ceh-8 homeobox protein (otd subfamily) status:Partially_confirmed SW:Q94398 protein_id:CAB03519.2 [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE38130 WBGene00000433 locus:ceh-8 homeobox protein (otd subfamily) status:Partially_confirmed UniProt:Q94398 protein_id:CAB03519.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE38130 WBGene00000433 locus:ceh-8 homeobox protein (otd subfamily) status:Partially_confirmed UniProt:Q94398 protein_id:CAB03519.2| [wormORF-contam.fasta]
  • Hypothetical protein ZK265.4 [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Homeobox protein ceh-8 [nr-271106-contam.fasta]
  • C.Elegans Homeobox family member (ceh-8) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE38130 WBGene00000433 locus:ceh-8 status:Partially_confirmed UniProt:Q94398 protein_id:CAB03519.2 Homeobox protein ceh-8 [wormpep246-ecoli-contam.fasta]
    • Organism: Caenorhabditis elegans
    Length: 276 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article][ISSLink to PubMed article]
    Biological Process: pattern specification process [TASLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]
    transcription regulator activity [ISSLink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNPTDNNSA TSSITPNFSA FSSFTTYKPS DSFSSFESDS SPSKSSSSRK NRDKIADKKQ  60
   61 RRNRTTFTTF QLHALEAAFD KTHYPDVYAR ETLAAKVQLP EVRVQVWFQN RRAKFRRQEK 120
  121 QDCQGEEKHS LKDTMPSWSW MSENKTDTPP MLPPANTLSS THNNGISDEF FKTSEGKEVY 180
  181 GFPFAEYGTP ADNTHVSKTG NVFHLNFEDS DKKSMKKESP QTPSTSSPFI SEYHPPFIPY 240
  241 YIPNQSFSNA FNQYPMPFPY PIHFEPPQLT HSQENC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..129] PSI-BLAST 25.0 Paired protein
    2 View Details [130..276] MSA 6.895995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.25140430108186 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.993707936114837 bayes_pls_golite062009
  • DNA binding
    		•  0.817622981651434 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.578037557340686 bayes_pls_golite062009
  • transcription factor activity
    		•  0.49956799334009 bayes_pls_golite062009
  • protein binding
    		•  0.134872960372588 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle