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Protein Overview: smk-1

General Information:
Name(s) found: smk-1 / CE37912 [WormBase]
Description(s) found:
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  • WBGene00018285 locus:smk-1 status:Confirmed UniProt:Q5NKY6 protein_id:CCD64082.1 [WormBase]
  • gi|71993911|ref|NP_001023911.1| SMEK (Dictyostelium Suppressor of MEK null) homolog family member (smk-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|56797832|gb|AAW30665.1| Smek (dictyostelium suppressor of mek null) homolog protein 1, isoform c [Caenorhabditis elegans] [NCBI NR]
  • CE37912 WBGene00018285 status:Confirmed TR:Q5NKY6 protein_id:AAW30665.1 [wormpep150.fasta]
  • 37912 WBGene00018285 status:Confirmed TR:Q5NKY6 protein_id:AAW30665.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE37912 WBGene00018285 locus:smk-1 status:Confirmed UniProt:Q5NKY6_CAEEL protein_id:AAW30665.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE37912 WBGene00018285 locus:smk-1 status:Confirmed UniProt:Q5NKY6_CAEEL protein_id:AAW30665.1| [wormORF-contam.fasta]
  • CE37912 WBGene00018285 locus:smk-1 status:Confirmed TR:Q5NKY6 protein_id:AAW30665.1 [wormpep160-contam.fasta]
  • SMEK (Dictyostelium Suppressor of MEK null) homolog family member (smk-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • Hypothetical protein F41E6.4c [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE37912 WBGene00018285 locus:smk-1 status:Confirmed UniProt:Q5NKY6 protein_id:AAW30665.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE37912 WBGene00018285 locus:smk-1 status:Confirmed UniProt:Q5NKY6 protein_id:CCD64082.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • Isoform of H2KYN6, SMEK (Dictyostelium Suppressor of MEK null) homolog OS=Caenorhabditis elegans GN=smk-1 PE=1 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 536 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: hermaphrodite genitalia development [IMPLink to PubMed articleLink to PubMed article]
    determination of adult lifespan [IGILink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    chromosome segregation [IMPLink to PubMed article]
    response to UV [IGILink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    response to DNA damage stimulus [IGILink to PubMed article]
    defense response to bacterium [IGILink to PubMed article][IMPLink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [IMPLink to PubMed article]
    oocyte construction [IMPLink to PubMed article]
    response to oxidative stress [IGILink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    oviposition [IMPLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDTKEVSDD PMELGTSSTV IAKEENDKES LKRMEVDDEK EPEEEIVEKT EEKQEEEDVT  60
   61 VKLEDETETE VESVDGGQEE KEVVDEKQVD AERVNTKTEE LSPKKEVKAE EDPETETKKK 120
  121 DPSEQTNGQV KKKSDKQSPK KKEKSEGKEN SPGSKLTNRD HILDHLDIKR DATNRVKLYV 180
  181 LCDQRIWEDR GTGHVVTHQL SAEDGAPSNA GNTMVLVRLE GQNKNMLESR IQMDTVYQKQ 240
  241 QETLIVWSET DVMDLALSFQ EKSGCEELWQ KICEVQGRDP GDPDATFDDG DDSDVGEMPS 300
  301 SASRLQLPPI EIGRLGELDA LLHMHLTTNS AREKMTLAIE NDNVVTKLCE VFRMCEDIEH 360
  361 TEGLRTFYSI VKNLFMLNRN TVIEMLLDDN NIKDVIGMFE FDPAYKHPRK HRDFVYKKAK 420
  421 FREVLNISCD ELRDKIHRLY RAQYIQDACL PSLGLFEENL LSTLSSHVFF CRVDIVTLLQ 480
  481 KDKKAMSELF GQLISEETDV IRRRDLALFL KEMISLSTSI PSNGPAATKE TFFKVV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..230] MSA 44.174997 View MSA. No confident structure predictions are available.
    2 View Details [231..308] deduced N/A No confident structure predictions are available.
    3 View Details [309..536] Pfam 41.09691 No description for PF04802.6 was found. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle