Protein Overview: nhr-23

General Information:
Name(s) found:	nhr-23 / CE39086 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00003622 locus:nhr-23 Nuclear hormone receptor family member nhr-23 status:Partially_confirmed UniProt:P41828 protein_id:CAJ30220.1 [WormBase] gi\|86560912\|ref\|NP_001032971.1\| Nuclear Hormone Receptor family member (nhr-23) [Caenorhabditis elegans] [NCBI NR] gi\|74834668\|emb\|CAJ30220.1\| C. elegans protein C01H6.5f, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] CE39086 WBGene00003622 locus:nhr-23 status:Partially_confirmed TR:Q3S1J2 protein_id:CAJ30220.1 [wormpep150.fasta] 39086 WBGene00003622 locus:nhr-23 status:Partially_confirmed TR:Q3S1J2 protein_id:CAJ30220.1 [wormpep150-phg-orf-ecoli-rand.fasta] CE39086 WBGene00003622 locus:nhr-23 status:Partially_confirmed UniProt:P41828 protein_id:CAJ30220.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE39086 WBGene00003622 locus:nhr-23 status:Partially_confirmed UniProt:P41828 protein_id:CAJ30220.1\| [wormORF-contam.fasta] Hypothetical protein C01H6.5f [Caenorhabditis elegans] [nr-271106-contam.fasta] Nuclear Hormone Receptor family member (nhr-23) [Caenorhabditis elegans] [nr-271106-contam.fasta] CE39086 WBGene00003622 locus:nhr-23 status:Partially_confirmed SW:P41828 protein_id:CAJ30220.1 [WormBase_C-elegans_wp180_08-19-2007_reversed.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE39086 WBGene00003622 locus:nhr-23 status:Partially_confirmed UniProt:P41828 protein_id:CAJ30220.1 Nuclear hormone receptor family member nhr-23 [wormpep246-ecoli-contam.fasta] Isoform of P41828, Isoform f of Nuclear hormone receptor family member nhr-23 OS=Caenorhabditis elegans GN=nhr-23 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	555 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA]
Biological Process:	molting cycle, protein-based cuticle [IMP] locomotory behavior [IMP ] nematode larval development [IMP ] post-embryonic body morphogenesis [IMP] regulation of transcription, DNA-dependent [IEA] oviposition [IMP] positive regulation of multicellular organism growth [IMP ] growth [IMP ] reproduction [IMP]
Molecular Function:	DNA binding [IEA] transcription factor activity [IEA] zinc ion binding [IEA] steroid hormone receptor activity [IEA] sequence-specific DNA binding [IEA] steroid binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQAVEQKLAD ATRTLHAKSS LQPSLSIETP KSKENDESGC ESSNCMFHPH TIKSEPNFCF  60
   61 AREFKSVPDD FRIGGGDLQM GNNSKRLTCV IDTNRVDMAG ILPDNMSFRG LPENKSLLVS 120
  121 AQIEVIPCKV CGDKSSGVHY GVITCEGCKG FFRRSQSSIV NYQCPRQKNC VVDRVNRNRC 180
  181 QYCRLKKCIE LGMSRDAVKF GRMSKKQREK VEDEVQVRMH KELAANGLGY QAIYGDYSPP 240
  241 PSHPSYCFDQ SMYGHYPSGT STPVNGYSIA VAATPTTPMP QNMYGATPSS TNGTQYVAHQ 300
  301 ATGGSFPSPQ VPEEDVATRV IRAFNQQHSS YTTQHGVCNV DPDCIPHLSR AGGWELFARE 360
  361 LNPLIQAIIE FAKSIDGFMN LPQETQIQLL KGSVFELSLV FAAMYYNVDA QAVCGERYSV 420
  421 PFACLIAEDD AEMQLIVEVN NTLQEIVHLQ PHQSELALLA AGLILEQVSS SHGIGILDTA 480
  481 TIATAETLKN ALYQSVMPRI GCMEDTIHRI QDVETRIRQT ARLHQEALQN FRMSDPTSSE 540
  541 KLPALYKELF TADRP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
transcription regulator activity	5.53061626347066	bayes_pls_golite062009
DNA binding	4.92165988569962	bayes_pls_golite062009
nucleic acid binding	4.78024150262074	bayes_pls_golite062009
transcription activator activity	4.53302455129434	bayes_pls_golite062009
sequence-specific DNA binding	4.11614358606713	bayes_pls_golite062009
transcription factor activity	4.0914094580319	bayes_pls_golite062009
ligand-dependent nuclear receptor activity	3.89763470197726	bayes_pls_golite062009
binding	3.85318710398432	bayes_pls_golite062009
transcription repressor activity	3.83878598697109	bayes_pls_golite062009
protein binding	3.21524787168952	bayes_pls_golite062009
transcription factor binding	2.68044489404568	bayes_pls_golite062009
receptor activity	2.62895787183554	bayes_pls_golite062009
ecdysteroid hormone receptor activity	2.42118322312622	bayes_pls_golite062009
RNA polymerase II transcription factor activity	2.38308182853979	bayes_pls_golite062009
steroid hormone receptor activity	2.30195937604451	bayes_pls_golite062009
molecular transducer activity	2.04709877069886	bayes_pls_golite062009
signal transducer activity	2.04709877069886	bayes_pls_golite062009
transcription cofactor activity	1.73827483890179	bayes_pls_golite062009
nuclear hormone receptor binding	1.60419100774741	bayes_pls_golite062009
retinoic acid receptor binding	1.59968001933699	bayes_pls_golite062009
retinoid X receptor binding	1.45560845709347	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	1.34794228300778	bayes_pls_golite062009
transcription coactivator activity	1.23834725221597	bayes_pls_golite062009
transcription corepressor activity	0.995333369475571	bayes_pls_golite062009
retinoic acid receptor activity	0.853869057774515	bayes_pls_golite062009
protein dimerization activity	0.797229273848179	bayes_pls_golite062009
hormone receptor binding	0.74373733735458	bayes_pls_golite062009
promoter binding	0.58091332905515	bayes_pls_golite062009
protein N-terminus binding	0.57701453824007	bayes_pls_golite062009
thyroid hormone receptor activity	0.49784404390361	bayes_pls_golite062009
protein heterodimerization activity	0.45265806678057	bayes_pls_golite062009
receptor binding	0.418843034756825	bayes_pls_golite062009
ligand-regulated transcription factor activity	0.202197503742221	bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding	0.15737167800277	bayes_pls_golite062009
catalytic activity	0.106902059021677	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..122]	MSA	14.457997	View MSA. No confident structure predictions are available.
2	View Details	[123..263]	PSI-BLAST	25.09691	Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter
3	View Details	[264..555]	PSI-BLAST	54.154902	LIGAND-BINDING DOMAIN OF THE HUMAN NUCLEAR RECEPTOR RXR-ALPHA

Protein Overview: nhr-23

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: