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Protein Overview: nas-15

General Information:
Name(s) found: nas-15 / CE38541 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00003534 locus:nas-15 Zinc metalloproteinase nas-15 status:Partially_confirmed UniProt:P55115 protein_id:CCD62714.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 571 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    Biological Process: proteolysis [IEALink to PubMed article]
    Molecular Function: meprin A activity [IEALink to PubMed article]
    zinc ion binding [IEALink to PubMed article]
    astacin activity [IEALink to PubMed article]
    metallopeptidase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREYVLIFLV APVFAAILGP YDIPPELPPL NDENFFDRSH SEYETVLTPE DFELGTRITA  60
   61 AMAHDNGDDI WDSDAMYSKD RFEGDIANDN LNASTAELFA NGGSGKSEDG KWYNAIKNRL 120
  121 QLWPEGRIPY TISSQYSSYS RSLIAASMQE YASHTCIRWV PKEAADVNYV HIYPDRGCYS 180
  181 MVGKMGGKQS LSLGSGCIQK GIILHELMHA VGFFHEQSRT DRDDHITIMW NNIQAGMQGQ 240
  241 FEKYGHGTIQ SLGTGYDYGS IMHYGTKAFS RNGQPTMIPK KNGATIGQRN GFSKVDKFKI 300
  301 NTLYGCPVEG EKPTTSAPTS GPIVITVKPV VITTGKPPVI QTVSPAVPLK PSECRNLRGD 360
  361 CDDLAKQGWC IRNPGWMRAN CPISCGMCIP TKETQKPYVQ TTTQAATTTA RPQKPVTQPI 420
  421 QPLPPVPPLP PTTPEDCEDL RVDCLVLVSQ RYCKISQNFM KSYCAKSCGF CFKPPPTEIP 480
  481 DNRPTVVTTR PLVTLPPAVI RSRSPAPPVS TTTKAAPTTS TTSAAPYSPT PLPSECSDRK 540
  541 HFCSHWKSAG FCEGIFMNYM KKNCPASCGL C

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..68] deduced N/A No confident structure predictions are available.
    2 View Details [69..229] PSI-BLAST 46.69897 STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
    3 View Details [230..571] PSI-BLAST 6.09691 Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  0.945822943902565 bayes_pls_golite062009
  • protein binding
    		•  0.513051538906644 bayes_pls_golite062009
  • catalytic activity
    		•  0.34605294925773 bayes_pls_golite062009
  • receptor binding
    		•  0.0218857243240818 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle