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View Structure Prediction Details

Protein: nas-15
Organism: Caenorhabditis elegans
Length: 571 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nas-15.

Description E-value Query
Range
Subject
Range
gi|187032900, gi... - gi|39592545|emb|CAE63622.1| Hypothetical protein CBG08116 [Caenorhabditis briggsae], gi|187032900|em...
gi|157766915 - gi|157766915|ref|XP_001666937.1| Hypothetical protein CBG08116 [Caenorhabditis briggsae AF16]
310.0 [0..1] [571..1]

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Predicted Domain #1
Region A:
Residues: [1-68]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MREYVLIFLV APVFAAILGP YDIPPELPPL NDENFFDRSH SEYETVLTPE DFELGTRITA  60
   61 AMAHDNGD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [69-229]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DIWDSDAMYS KDRFEGDIAN DNLNASTAEL FANGGSGKSE DGKWYNAIKN RLQLWPEGRI  60
   61 PYTISSQYSS YSRSLIAASM QEYASHTCIR WVPKEAADVN YVHIYPDRGC YSMVGKMGGK 120
  121 QSLSLGSGCI QKGIILHELM HAVGFFHEQS RTDRDDHITI M

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.69897
Match: 1astA
Description: STRUCTURE OF ASTACIN AND IMPLICATIONS FOR ACTIVATION OF ASTACINS AND ZINC-LIGATION OF COLLAGENASES
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [230-571]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WNNIQAGMQG QFEKYGHGTI QSLGTGYDYG SIMHYGTKAF SRNGQPTMIP KKNGATIGQR  60
   61 NGFSKVDKFK INTLYGCPVE GEKPTTSAPT SGPIVITVKP VVITTGKPPV IQTVSPAVPL 120
  121 KPSECRNLRG DCDDLAKQGW CIRNPGWMRA NCPISCGMCI PTKETQKPYV QTTTQAATTT 180
  181 ARPQKPVTQP IQPLPPVPPL PPTTPEDCED LRVDCLVLVS QRYCKISQNF MKSYCAKSCG 240
  241 FCFKPPPTEI PDNRPTVVTT RPLVTLPPAV IRSRSPAPPV STTTKAAPTT STTSAAPYSP 300
  301 TPLPSECSDR KHFCSHWKSA GFCEGIFMNY MKKNCPASCG LC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.09691
Match: 1n7dA
Description: Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.945822943902565 bayes_pls_golite062009
protein binding 0.513051538906644 bayes_pls_golite062009
catalytic activity 0.34605294925773 bayes_pls_golite062009
receptor binding 0.0218857243240818 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle