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Protein Overview: pig-1

General Information:
Name(s) found: pig-1 / CE40473 [WormBase]
Description(s) found:
Found 13 descriptions.
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  • WBGene00021012 locus:pig-1 status:Confirmed UniProt:A7WK47 protein_id:CCD69087.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 703 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: asymmetric cell division [IMPLink to PubMed article]
    generation of neurons [IMPLink to PubMed article]
    cell fate specification [IMPLink to PubMed article]
    protein amino acid phosphorylation [IEALink to PubMed article]
    Molecular Function: magnesium ion binding [IEALink to PubMed article]
    ATP binding [IEALink to PubMed article]
    protein tyrosine kinase activity [IEALink to PubMed article]
    protein kinase activity [IEALink to PubMed article]
    protein serine/threonine kinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKYEVLQGF YAVHDELGSG GFGKVRLATH LLTNQKVAIK IIDKKQLGHD LPRVQTEMDA  60
   61 LRNLSHQNIC RLYHYIETED KFFIVMEYCS GGEMFDYIVR KERLEESEAR HFFRQLVSAI 120
  121 AFVHSQGYAH RDLKPENLLL TEDLHLKLID FGLCAKTEKG RIDKHNLDTC CGSPAYAAPE 180
  181 LIQGLQYKGN EADVWSMGIL LYTLLVGALP FEDDNMQIMY KKIQSGCFYE PEFLSPLSKQ 240
  241 LLRAMLQVVP ERRISVKKLL EHDWLNHKYT QPVKWNTIYD KNFIDRDVAR VMSKYYGFES 300
  301 TDKMIEKIKE WNFDYMTSTY YALLHRKRNG MEIILPMVRN STNTAPPNVQ NILCSPTIHA 360
  361 SLENNLDKSG LEDDDSDPSS ISSSSDISAR LKKNCVVSDE SSSSRFVKPM SPAAEKDKKM 420
  421 SYVNAMLTMP SQFTGRSPLR IPESPMSVRS SDSASLGSAA TPSRGGVKDN DKENASTGKN 480
  481 YRMGASTCKS RGPLKITGVE EGTMKSVYTT PNTRPTLRGL FSPGNAEHKK RQRARSSDRA 540
  541 SIGMPPGSPV SIGSAHSANN ADGRTPRSRI KTNRLPQRVF TSLERKKEKL ITLLTPRKMQ 600
  601 RDSPQVLKDV KNMVNVSMTA SQDPEEVRNL LKKVFDDERM RYELNGWKFL ATQETVHGWM 660
  661 TVELEIVRLQ MFDKVGIRRK RLKGDAFMYK KVCEKILQMA KIE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..397] PSI-BLAST 85.0 No description for 2qnjA was found.
    2 View Details [398..582] deduced N/A No confident structure predictions are available.
    3 View Details [583..703] PSI-BLAST 35.30103 Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • protein kinase activity
    		•  4.05475891009228 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  4.04751809021925 bayes_pls_golite062009
  • kinase activity
    		•  3.88704262604357 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  3.7974128326421 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  3.55786569314106 bayes_pls_golite062009
  • transferase activity
    		•  2.750643926194 bayes_pls_golite062009
  • binding
    		•  2.41732321506551 bayes_pls_golite062009
  • ATP binding
    		•  1.44435058039859 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.41005152726625 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.38971642420542 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.16863558166547 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.16859376715941 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.15633908642115 bayes_pls_golite062009
  • nucleotide binding
    		•  1.14964488472581 bayes_pls_golite062009
  • catalytic activity
    		•  0.836142537655721 bayes_pls_golite062009
  • protein binding
    		•  0.704339182896017 bayes_pls_golite062009
  • AMP-activated protein kinase activity
    		•  0.496765880715405 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.439688030503848 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle