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Protein Overview: oct-1

General Information:
Name(s) found: oct-1 / CE41244 [WormBase]
Description(s) found:
Found 11 descriptions.
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  • WBGene00003842 locus:oct-1 Organic cation transporter 1 status:Confirmed UniProt:Q9U539 protein_id:CAB05732.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 585 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    Biological Process: ion transport [IEALink to PubMed article]
    phosphate transport [IEALink to PubMed article]
    carbohydrate transport [IEALink to PubMed article]
    transport [IEALink to PubMed article]
    Molecular Function: inorganic phosphate transmembrane transporter activity [IEALink to PubMed article]
    carbohydrate transmembrane transporter activity [IEALink to PubMed article]
    ion transmembrane transporter activity [IEALink to PubMed article]
    sugar:hydrogen symporter activity [IEALink to PubMed article]
    transporter activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFQAMETFA EISQEILMSA TKPPDFDFVL EQVGNYGTYQ IVFFFIICLP TSLPSAFSAF  60
   61 NIPFVVGNPP HTCHIPEGKE YLRPLTNDTQ ILSCKQYNET QINVFRAFTS APVDTYSDRI 120
  121 SLVPCQNGWD YDNSTYLDSL VTEFNLVCDQ QAWIEISTTS FYVGSFIGNC LFGYVADKFG 180
  181 RRRSFFVILT VLIVCGTASS FAKDIESFII LRFFTGLAFP ALFQIPFIIC MEFMGNSGRI 240
  241 FSGLMTSLFF GAAMALLGVV AMFIRRWRQL TFFCNAPFAF YIIYYFFLPE SPRWSVSVGK 300
  301 WADAKKQLKK IAKMNGKSNV DVDELVDSMK NHQNAAEEKE TKRSHNVTDL FKTPNLRRKT 360
  361 LIVTYIWVMN AIIYNGLTLN VSNLPVDDYW SFIINGAVEL PGYFVVWPLL QCAGRRWTLA 420
  421 ATMIVCGIGC VSAMFMPDGY PWLVASASFI GKFGVGSGFA VIYIFAGELY PTVVRAIGMG 480
  481 MSSMVAGSGL LLAPHIVNLG KIVKILPLLI MGLMALSAGI LTFFLPETLG APLPMTIEDA 540
  541 ENFGKKPEPD SGMFTQAAKK RESQPLLEPH TPMDRRRRSS RLMNI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..115] deduced N/A No confident structure predictions are available.
    2 View Details [116..585] PSI-BLAST 30.69897 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.31967711223954 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.94605227012838 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • organic anion transmembrane transporter activity
    		•  3.3413526350788 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  3.21476253433572 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  2.87308506088228 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  2.87308506088228 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • binding
    		•  1.89539096965643 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  1.47932844880848 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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