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Protein Overview: Rassf-PA

General Information:
Name(s) found: Rassf-PA / FBpp0083799 [FlyBase]
Description(s) found:
Found 17 descriptions.
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  • The gene Ras association family member is referred to in FlyBase by the symbol Dmel\Rassf (CG4656, FBgn0039055). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:18939736..18943673. It has the cytological map location 94D13-94E1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: response to gamma radiation; regulation of multicellular organism growth; negative regulation of signal transduction. 14 alleles are reported. The phenotype of these alleles is annotated with: wing. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 806 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: regulation of multicellular organism growth [IMP]
    negative regulation of signal transduction [IMP]
    response to gamma radiation [IMP]
    Molecular Function: zinc ion binding [IEA]
    protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWKCHKCGKP VYFAERKQSI GYDWHPECLR CEECGKRLNP GQHAEHKSVP YCHVPCYGAL  60
   61 FGPQLFGHGT RVESHKSYGV KGAQKPTGAQ ANGPPLPRDH LESKLKVYNQ FYDNKSLEIR 120
  121 SREVNNRLVL EGALRVYWGV QGVIHLKEDD DQRILVRKRN SCRVSKAANE SSSDKENEAS 180
  181 ESLAPPTTTT AEVDQLSTDV SLSESMTFDS CSLNEISELP TTPEDASANT TANSKEQTNG 240
  241 NVCNDDEDTT TTDSSGTLVE APTASTSCVS STLPSKLDRL EKLDWDDIDD LLQVERRHND 300
  301 KDRIYETMPV KLPSSQSSSD SSPSKTSTET TTTTESSSTQ SASTNTSSTD DFMTATGSLT 360
  361 ANTNTQNTTT VSTTETSLDN FETCDDATLK PIDFEDFKRS VHQDYVNGAN SFTEPNEGTL 420
  421 KRNQPIDPSR IHDSLKLYGE NSAMSKSFNC EHALRSIDPT LINDTMNLRS SVGSPHSAQR 480
  481 QYALQKSGSA TVTSRDQKKP YQQGRQLFEK GINRSKSGPS CFVYSDSDDD DEATLRPQRM 540
  541 ATIRRSDIPQ RYIQIQMDCY PKENVAAASE GESSRADAPS ITSGAAAGDE LTQTEDLYTA 600
  601 SEGVDGPDGD GSAGLHVTED GVVLRRPPRT GASAIKRRSG NRRSRTKLKR RCSINGHYYN 660
  661 RETSFFTPPY GSQMSVWVSS MVTTTEVINL VLEKYKVDSS PGNFSLFIVR DNGEQKRLKD 720
  721 DEYPLITRVT LGPHEDVARI FLVDSRKTDE ISNEVAQFLN LSLPECRAIL ERYDQELARE 780
  781 VAKIKERYAE LRRRIVSRME SLKVHL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..78] PSI-BLAST 20.69897 CYSTEINE RICH INTESTINAL PROTEIN, NMR, 48 STRUCTURES
    2 View Details [79..138] deduced N/A No confident structure predictions are available.
    3 View Details [139..523] FFAS03 0.975 THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
    4 View Details [524..671] deduced N/A No confident structure predictions are available.
    5 View Details [672..806] FFAS03 1.57 Solution Structure of Ras-binding Domain in Mouse AF-6 Protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.32420977112004 bayes_pls_golite062009
  • protein binding
    		•  1.39455913713025 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.18816040284456 bayes_pls_golite062009
  • DNA binding
    		•  1.00346200943179 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.86280381479968 bayes_pls_golite062009
  • transcription factor activity
    		•  0.441713135779151 bayes_pls_golite062009
  • transcription factor binding
    		•  0.30385317974375 bayes_pls_golite062009
  • receptor activity
    		•  0.230063209127305 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • binding
    		•  2.0688320293797 bayes_pls_golite062009
  • protein binding
    		•  1.72968950672856 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle