Protein Overview: LOX5_MOUSE

General Information:
Name(s) found:	LOX5_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|886333\|gb\|AAC37673.1\| arachidonate 5-lipoxygenase [Mus musculus] [NCBI NR] pir\|\|I49479 arachidonate 5-lipoxygenase - mouse (fragment) [NCBI NR] gi\|1346465\|sp\|P48999.2\|LOX5_MOUSE RecName: Full=Arachidonate 5-lipoxygenase; Short=5-lipoxygenase; Short=5-LO [NCBI NR] Arachidonate 5-lipoxygenase OS=Mus musculus GN=Alox5 PE=1 SV=2 [Swiss-Prot] arachidonate 5-lipoxygenase [Mus musculus]gi\|2117635\|pir\|\|I49479 arachidonate 5-lipoxygenase - mouse (fragment)gi\|1346465\|sp\|P48999\|LOX5_MOUSE Arachidonate 5-lipoxygenase (5-lipoxygenase) (5-LO) [nrdb_11152004_Chlamydomonas] Arachidonate 5-lipoxygenase (5-lipoxygenase) (5-LO) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] arachidonate 5-lipoxygenase [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Alox5 Arachidonate 5-lipoxygenase [mouse-ipi-250309-contam.fasta] IPI:IPI00115652.5\|SWISS-PROT:P48999 Tax_Id=10090 Gene_Symbol=Alox5 Arachidonate 5-lipoxygenase [ipi.MOUSE.fasta.20090209] Arachidonate 5-lipoxygenase OS=Mus musculus GN=Alox5 [011711_HMR.fasta]
Organism:	Mus musculus
Length:	674 amino acids
Gene Ontology:
Cellular Component:	nuclear envelope [UNKNOWN] nucleus [UNKNOWN][IDA] dendrite [UNKNOWN] soluble fraction [UNKNOWN] cytoplasm [IDA] sarcolemma [UNKNOWN] membrane [IEA]
Biological Process:	inflammatory response [IMP] leukotriene biosynthetic process [IDA][IMP] leukotriene metabolic process [IMP] acute inflammatory response [UNKNOWN] lipoxygenase pathway [UNKNOWN] positive regulation of vasoconstriction [UNKNOWN] sensory perception of pain [UNKNOWN] oxidation reduction [IEA] leukotriene production involved in inflammatory response [IMP] arachidonic acid metabolic process [UNKNOWN]
Molecular Function:	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen [IEA] metal ion binding [IEA] oxidoreductase activity [IEA] iron ion binding [IEA] arachidonate 5-lipoxygenase activity [UNKNOWN] lipoxygenase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSYTVTVAT GSQWFAGTDD YIYLSLIGSA GCSEKHLLDK AFYNDFERGA VDSYDVTVDE  60
   61 ELGEIYLVKI EKRKYWLHDD WYLKYITLKT PHGDYIEFPC YRWITGEGEI VLRDGRAKLA 120
  121 RDDQIHILKQ HRRKELEARQ KQYRWMEWNP GFPLSIDAKC HKDLPRDIQF DSEKGVDFVL 180
  181 NYSKAMENLF INRFMHMFQS SWHDFADFEK IFVKISNTIS ERVKNHWQED LMFGYQFLNG 240
  241 CNPVLIKRCT ALPPKLPVTT EMVECSLERQ LSLEQEVQEG NIFIVDYELL DGIDANKTDP 300
  301 CTHQFLAAPI CLLYKNLANK IVPIAIQLNQ TPGESNPIFL PTDSKYDWLL AKIWVRSSDF 360
  361 HVHQTITHLL RTHLVSEVFG IAMYRQLPAV HPLFKLLVAH VRFTIAINTK AREQLICEYG 420
  421 LFDKANATGG GGHVQMVQRA VQDLTYSSLC FPEAIKARGM DSTEDMPFYF YRDDGLLVWE 480
  481 AIQSFTMEVV SIYYENDQVV EEDQELQDFV KDVYVYGMRG KKASGFPKSI KSREKLSEYL 540
  541 TVVIFTASAQ HAAVNFGQYD WCSWIPNAPP TMRAPPPTAK GVVTIEQIVD TLPDRGRSCW 600
  601 HLGAVWALSQ FQENELFLGM YPEEHFIEKP VKEAMIRFRK NLEAIISVIA ERNKNKKLPY 660
  661 YYLSPDRIPN SVAI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: LOX5_MOUSE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: