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Protein Overview: tph-1

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

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[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..78] PSI-BLAST 40.0 No description for 2qmxA was found.
2 View Details [79..532] PSI-BLAST 153.0 Phenylalanine hydroxylase N-terminal domain; Phenylalanine hydroxylase, PAH

Functions predicted (by domain):

# Gene Ontology predictions
1 No functions predicted.
2
Term Confidence Notes
  • tyrosine 3-monooxygenase activity
  • 10.4963678823868 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
  • 10.3746889036269 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
  • 4.1759203417536 bayes_pls_golite062009
  • phenylalanine 4-monooxygenase activity
  • 4.03306427400343 bayes_pls_golite062009
  • acetolactate synthase activity
  • 3.48670706716817 bayes_pls_golite062009
  • monooxygenase activity
  • 3.40046054657404 bayes_pls_golite062009
  • tryptophan 5-monooxygenase activity
  • 2.77661203376054 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
  • 2.5269324625528 bayes_pls_golite062009
  • binding
  • 1.94530534071622 bayes_pls_golite062009
  • protein binding
  • 1.5818067110205 bayes_pls_golite062009
  • ferric iron binding
  • 1.39368895479267 bayes_pls_golite062009
  • amine binding
  • 1.23106204610034 bayes_pls_golite062009
  • transcription regulator activity
  • 1.16507349262706 bayes_pls_golite062009
  • catalytic activity
  • 0.932947046865376 bayes_pls_golite062009
  • DNA binding
  • 0.395475529920613 bayes_pls_golite062009
  • nucleic acid binding
  • 0.389893743151944 bayes_pls_golite062009




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle