| Protein: | tph-1 |
| Organism: | Caenorhabditis elegans |
| Length: | 532 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for tph-1.
| Description | E-value | Query Range |
Subject Range |
|
|
624.0 | [0..31] | [531..1] |
|
Region A: Residues: [1-78] |
1 11 21 31 41 51
| | | | | |
1 MDSLFQMASA MKFQYYSKKA AGKTMSNSVS MSSDNRMEDF KRRFRRSGSL GIPFVPEEDV 60
61 KQLFTPTRTV RREASIRE
|
| Detection Method: |  |
| Confidence: | 40.0 |
| Match: | 2qmxA |
| Description: | No description for 2qmxA was found. |
|
Region A: Residues: [79-532] |
1 11 21 31 41 51
| | | | | |
1 GDEEEGVQIL TIIVKSSRVS EDISKMIANL PDHTRIKHLE TRDSQDGSSK TMDVLLEIEL 60
61 FHYGKQEAMD LMRLNGLDVH EVSSTIRPTA IKEQYTEPGS DDATTGSEWF PKSIYDLDIC 120
121 AKRVIMYGAG LDADHPGFKD TEYRQRRMMF AELALNYKHG EPIPRTEYTS SERKTWGIIY 180
181 RKLRELHKKH ACKQFLDNFE LLERHCGYSE NNIPQLEDIC KFLKAKTGFR VRPVAGYLSA 240
241 RDFLAGLAYR VFFCTQYVRH HADPFYTPEP DTVHELMGHM ALFADPDFAQ FSQEIGLASL 300
301 GASEEDLKKL ATLYFFSIEF GLSSDDAADS PVKENGSNHE RFKVYGAGLL SSAGELQHAV 360
361 EGSATIIRFD PDRVVEQECL ITTFQSAYFY TRNFEEAQQK LRMFTNNMKR PFIVRYNPYT 420
421 ESVEVLNNSR SIMLAVNSLR SDINLLAGAL HYIL
|
| Detection Method: | |
| Confidence: | 153.0 |
| Match: | 1phzA |
| Description: | Phenylalanine hydroxylase N-terminal domain; Phenylalanine hydroxylase, PAH |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| tyrosine 3-monooxygenase activity | 10.4963678823868 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen | 10.3746889036269 | bayes_pls_golite062009 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 4.1759203417536 | bayes_pls_golite062009 |
| phenylalanine 4-monooxygenase activity | 4.03306427400343 | bayes_pls_golite062009 |
| acetolactate synthase activity | 3.48670706716817 | bayes_pls_golite062009 |
| monooxygenase activity | 3.40046054657404 | bayes_pls_golite062009 |
| tryptophan 5-monooxygenase activity | 2.77661203376054 | bayes_pls_golite062009 |
| transferase activity, transferring aldehyde or ketonic groups | 2.5269324625528 | bayes_pls_golite062009 |
| binding | 1.94530534071622 | bayes_pls_golite062009 |
| protein binding | 1.5818067110205 | bayes_pls_golite062009 |
| ferric iron binding | 1.39368895479267 | bayes_pls_golite062009 |
| amine binding | 1.23106204610034 | bayes_pls_golite062009 |
| transcription regulator activity | 1.16507349262706 | bayes_pls_golite062009 |
| catalytic activity | 0.932947046865376 | bayes_pls_golite062009 |
| DNA binding | 0.395475529920613 | bayes_pls_golite062009 |
| nucleic acid binding | 0.389893743151944 | bayes_pls_golite062009 |
