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Protein Overview: gi|4377730

General Information:
Name(s) found: gi|4377730 [NCBI NR]
Description(s) found:
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  • gi|4377730|gb|AAD19218.1| GTP cyclohydrolase I [Plasmodium falciparum] [NCBI NR]
  • GTP cyclohydrolase I [Plasmodium falciparum 3D7]gi|23496762|gb|AAN36317.1| GTP cyclohydrolase I [Plasmodium falciparum 3D7]gi|4377730|gb|AAD19218.1| GTP cyclohydrolase I [Plasmodium falciparum] [nrdb_11152004_Chlamydomonas]
  • GTP cyclohydrolase I [Plasmodium falciparum] [nr-271106-contam.fasta]
    • Organism: Plasmodium falciparum
    Length: 389 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: folic acid and derivative biosynthetic process [ISSLink to PubMed article]
    one-carbon metabolic process [ISSLink to PubMed article]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYKYTSINKS DKIYETHNME EKKKKGNNNN FSGLLNNEID DNNKKEKLKN SISKMYSNHK  60
   61 NRENFNECEK EDLVVIDEKD NNKKKKKNMT NTFEQDNNYN MNDNKRLGSF FKINDKCESI 120
  121 NENVNNINKQ SLKDSILFDN INEKEYFNET KEENKEGNKS NDIEKINCMK VKKKTVKKNK 180
  181 KKINKIINNK NKISKSNDIE EQIINISKHI YKILNISKLP KCDILKRTNR RYAETFLYLT 240
  241 NGYNLDIEQI IKRSLYKRMY KNNSIIKVTG IHIYSLCKHH LLPFEGTCDI EYIPNKYIIG 300
  301 LSKFSRIVDV FSRRLQLQED LTNDICNALK KYLKPLYIKV SIVAKHLCIN MRGVKEHDAK 360
  361 TITYASYKAE KENPTVHSLN IDSSVENLN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..165] MSA 10.090997 View MSA. No confident structure predictions are available.
    2 View Details [166..389] PSI-BLAST 80.154902 GTP cyclohydrolase I

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • GTP cyclohydrolase I activity
    		•  4.32142445441644 bayes_pls_golite062009
  • cyclohydrolase activity
    		•  4.12134839958676 bayes_pls_golite062009
  • GTP cyclohydrolase activity
    		•  3.76376266092452 bayes_pls_golite062009
  • catalytic activity
    		•  2.57832156213163 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
    		•  2.13367928146634 bayes_pls_golite062009
  • dihydroneopterin aldolase activity
    		•  2.05627605013559 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  1.46072575729571 bayes_pls_golite062009
  • 6-pyruvoyltetrahydropterin synthase activity
    		•  0.11818000438771 bayes_pls_golite062009
  • lyase activity
    		•  0.0597333135477298 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle