Protein Overview: gi|22124023, gi|...

General Information:
Name(s) found:	gi\|22124023 [NCBI NR] gi\|21956766 [NCBI NR]
Description(s) found: Found 4 descriptions. SHOW ALL	gi\|22124023\|ref\|NP_667446.1\| bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [Yersinia pestis KIM] [NCBI NR] gi\|21956766\|gb\|AAM83697.1\|AE013610_9 (p)ppGpp synthetase II [Yersinia pestis KIM] [NCBI NR]
Organism:	Yersinia pestis KIM10+
Length:	702 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYLFESLNLL IQRYLPEEQI KRLKQAYLVA RDAHEGQTRS SGEPYITHPV AVACILAEMR  60
   61 LDYETLMAAL LHDVIEDTPA TYQDMEQLFG KSVAELVEGV SKLDKLNFRD KKEAQAENFR 120
  121 KMIMAMVQDI RVILIKLADR THNMRTLGSL RPDKRRRIAR ETLEIYSPLA HRLGIHHLKT 180
  181 ELEELGFEAL YPNRYRVIKE VVKAARGNRK EMIQKILAEI EGRLTEAGIP CRVSGREKHL 240
  241 YSIYCKMHLK EQRFHSIMDI YAFRVIVKEV DTCYRVLGQA HSLYKPRPGR VKDYIAIPKA 300
  301 NGYQSLHTSL IGPHGVPVEV QIRTEDMDQM AEMGVAAHWA YKEQGESGTT AQIRAQRWMQ 360
  361 SLLELQQSAG SSFEFIESVK SDLFPDEIYV FTPEGRIVEL PAGATPVDFA YVVHTDIGHA 420
  421 CVGARVDRQP YPLSQPLSSG QTVEIITAPG ARPNAAWLNF VVSSKARAKI RQLLKNLKRD 480
  481 ESVSLGRRLL NHALGNGRKL SDISEENIKH ELDRMKLATV DDLLAEIGLG NAMSVVVAKN 540
  541 LLGDPSTLGT SASGTRKLPI KGADGVLITF AKCCRPIPGD PIIAHISPGK GLVIHHESCR 600
  601 NIRGYQKEPE KFMAVEWDQE TEQEFIAEIK VDMFNQQGAL ANLTAAINAA ESNIQSLNTE 660
  661 EKDGRVYSAF IRLTTRNRVH LANIMRKIRI MPDVVKVSRN RN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..383]	PSI-BLAST	132.0	Crystal structure of the bifunctional catalytic fragment of RelSeq, the RelA/SpoT homolog from Streptococcus equisimilis.
2	View Details	[384..608]	PSI-BLAST	28.0	Threonyl-tRNA synthetase (ThrRS), C-terminal domain; Threonyl-tRNA synthetase (ThrRS), N-terminal 'additional' domain; Threonyl-tRNA synthetase (ThrRS), second 'additional' domain; Threonyl-tRNA synthetase (ThrRS)
3	View Details	[609..702]	PSI-BLAST	12.30103	Crystal structure of the regulatory subunit of acetohydroxyacid synthase isozyme III from E. coli

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
GTP diphosphokinase activity	1.5953523101767	bayes_pls_golite062009
cyclic-nucleotide phosphodiesterase activity	1.53556412385088	bayes_pls_golite062009
3',5'-cyclic-nucleotide phosphodiesterase activity	1.52960140313397	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.17940277430091	bayes_pls_golite062009
guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity	1.1479499593037	bayes_pls_golite062009
diphosphoric monoester hydrolase activity	1.1479499593037	bayes_pls_golite062009
catalytic activity	1.122769147009	bayes_pls_golite062009
nucleotidyltransferase activity	0.92178707322923	bayes_pls_golite062009
hydrolase activity	0.89382287998944	bayes_pls_golite062009
phosphoric diester hydrolase activity	0.874654356902841	bayes_pls_golite062009
transferase activity	0.63270331673446	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.262138492248739	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.196287846714023	bayes_pls_golite062009
3',5'-cyclic-AMP phosphodiesterase activity	0.0897894719596	bayes_pls_golite062009
3',5'-cyclic-GMP phosphodiesterase activity	0.0229959143092802	bayes_pls_golite062009

2

No functions predicted.

3

Term	Confidence	Notes
transferase activity, transferring aldehyde or ketonic groups	1.58611270031811	bayes_pls_golite062009
catalytic activity	1.01569611874813	bayes_pls_golite062009
binding	0.162590183060409	bayes_pls_golite062009
transferase activity	0.07375530569672	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle