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Protein Overview: gi|16762568

General Information:
Name(s) found: gi|16762568 [NCBI NR]
Description(s) found:
Found 4 descriptions.
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  • gi|16762568|ref|NP_458185.1| bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [Salmonella enterica subsp. enterica serovar Typhi str. CT18] [NCBI NR]
    • Organism: Salmonella enterica subsp. enterica serovar Typhi str. CT18
    Length: 703 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYLFESLNQL IQTYLPEDQI KRLRQAYLVA RDAHEGQTRS SGEPYITHPV AVACILAEMK  60
   61 LDYETLMAAL LHDVIEDTPA TYQDMEQLFG KSVAELVEGV SKLDKLKFRD KKEAQAENFR 120
  121 KMIMAMVQDI RVILIKLADR THNMRTLGSL RPDKRRRIAR ETLEIYSPLA HRLGIHHIKT 180
  181 ELEELGFEAL YPNRYRVIKE VVRAARGNRK EMIQKILSEI EGRLQEAGIP CRVSGREKHL 240
  241 YSIYCKMVLK EQRFHSIMDI YAFRVIVHDS DTCYRVLGQM HSLYKPRPGR VKDYIAIPKA 300
  301 NGYQSLHTSM IGPHGVPVEV QIRTEDMDQM AEMGVAAHWA YKEHGETSTT AQIRAQRWMQ 360
  361 SLLELQQSAG SSFEFIESVK SDLFPDEIYV FTPEGRIVEL PAGATPVDFA YAVHTDIGHA 420
  421 CVGARVDRQP YPLSQPLSSG QTVEIITAPG ARPNAAWLNF VVSSKARAKI RQLLKNLKRD 480
  481 DSVSLGRRLL NHALGGSRKL AEIPQENIQR ELDRMKLATL DDLLAEIGLG NAMSVVVAKN 540
  541 LQQGEAVVPT VAQSNHGHLP IKGADGVLIT FAKCCRPIPG DPIIAHVSPG KGLVIHHESC 600
  601 RNIRGYQKEP EKFMAVEWDK ETEQEFITEI KVEMFNHQGA LANLTAAINT TTSNIQSLNT 660
  661 EEKDGRVYST FIRLTARDRV HLANIMRKIR VMPDVIKVTR NRN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..383] PSI-BLAST 134.0 Crystal structure of the bifunctional catalytic fragment of RelSeq, the RelA/SpoT homolog from Streptococcus equisimilis.
    2 View Details [384..621] PSI-BLAST 30.154902 Threonyl-tRNA synthetase (ThrRS), C-terminal domain; Threonyl-tRNA synthetase (ThrRS), N-terminal 'additional' domain; Threonyl-tRNA synthetase (ThrRS), second 'additional' domain; Threonyl-tRNA synthetase (ThrRS)
    3 View Details [622..703] PSI-BLAST 12.522879 Crystal structure of the regulatory subunit of acetohydroxyacid synthase isozyme III from E. coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • GTP diphosphokinase activity
    		•  1.5953523101767 bayes_pls_golite062009
  • cyclic-nucleotide phosphodiesterase activity
    		•  1.53556412385088 bayes_pls_golite062009
  • 3',5'-cyclic-nucleotide phosphodiesterase activity
    		•  1.52960140313397 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.17940277430091 bayes_pls_golite062009
  • guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity
    		•  1.1479499593037 bayes_pls_golite062009
  • diphosphoric monoester hydrolase activity
    		•  1.1479499593037 bayes_pls_golite062009
  • catalytic activity
    		•  1.122769147009 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.92178707322923 bayes_pls_golite062009
  • hydrolase activity
    		•  0.89382287998944 bayes_pls_golite062009
  • phosphoric diester hydrolase activity
    		•  0.874654356902841 bayes_pls_golite062009
  • transferase activity
    		•  0.63270331673446 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.262138492248739 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.196287846714023 bayes_pls_golite062009
  • 3',5'-cyclic-AMP phosphodiesterase activity
    		•  0.0897894719596 bayes_pls_golite062009
  • 3',5'-cyclic-GMP phosphodiesterase activity
    		•  0.0229959143092802 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • transferase activity, transferring aldehyde or ketonic groups
    		•  1.58611270031811 bayes_pls_golite062009
  • catalytic activity
    		•  1.01569611874813 bayes_pls_golite062009
  • binding
    		•  0.162590183060409 bayes_pls_golite062009
  • transferase activity
    		•  0.07375530569672 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle