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Protein Overview: unc-62

General Information:
Name(s) found: unc-62 / CE37795 [WormBase]
Description(s) found:
Found 15 descriptions.
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  • WBGene00006796 locus:unc-62 Homeobox protein unc-62 status:Confirmed UniProt:Q9N5D6 protein_id:CCD72267.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 490 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: oocyte construction [IMPLink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    regulation of transcription, DNA-dependent [IEALink to PubMed article]
    oviposition [IMPLink to PubMed articleLink to PubMed article]
    cell migration [IMPLink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    Molecular Function: transcription factor activity [IEALink to PubMed article]
    sequence-specific DNA binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGAPTSTPM MHHEMGEAMK RDKESIYAHP LYPLLVLLFE KCELATSTPR DTSRDGSTSS  60
   61 DVCSSASFKD DLNEFVRHTQ ENADKQYYVP NPQLDQIMLQ SIQMLRFHLL ELEKVHELCD 120
  121 NFCNRYVVCL KGKMPLDIVG DERASSSQPP MSPGSMGHLG HSSSPSMAGG ATPMHYPPPY 180
  181 EPQSVPLPEN AGVMGGHPME GSSMAYSMAG MAAAAASSSS SSNQAGDHPL ANGGTLHSTA 240
  241 GASQTLLPIA VSSPSTCSSG GLRQDSTPLS GETPMGHANG NSMDSISEAG DEFSVCGSND 300
  301 DGRDSVLSDS ANGSQNGKRK VPKVFSKEAI TKFRAWLFHN LTHPYPSEEQ KKQLAKETGL 360
  361 TILQVNNWFI NARRRIVQPM IDQNNRAGRS GQMNVCKNRR RNRSEQSPGP SPDSGSDSGA 420
  421 NYSPDPSSLA ASTAMPYPAE FYMQRTMPYG GFPSFTNPAM PFMNPMMGFQ VAPTVDALSQ 480
  481 QWVDLSAPHE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..166] MSA 9.550979 View MSA. No confident structure predictions are available.
    2 View Details [167..302] deduced N/A No confident structure predictions are available.
    3 View Details [303..386] PSI-BLAST 19.69897 Crystal Structure of HoxA9 and Pbx1 homeodomains bound to DNA
    4 View Details [387..490] MSA 4.377996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  1.62959077995642 bayes_pls_golite062009
  • binding
    		•  1.48969201384255 bayes_pls_golite062009
  • DNA binding
    		•  1.2137926921894 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.02805703044131 bayes_pls_golite062009
  • transcription factor activity
    		•  0.89626527070971 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.06790788268651 bayes_pls_golite062009
  • protein binding
    		•  0.012115247005138 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle