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Protein Overview: gi|619233, gi|21...

General Information:
Name(s) found: gi|619233 [NCBI NR]
gi|2118418 [NCBI NR]
gi|1881814 [NCBI NR]
Description(s) found:
Found 7 descriptions.
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  • gi|619233|gb|AAC60687.1| tissue inhibitor of metalloproteinase type 2; TIMP-2 [Rattus sp.] [NCBI NR]
  • gi|2118418|pir||I53415 tissue inhibitor of metalloproteinase type 2 - rat [NCBI NR]
  • gi|1881814|gb|AAB49507.1| TIMP-2 [Rattus sp.] [NCBI NR]
    • Organism: Rattus sp.
    Length: 220 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGAAARSLRL ALGLLLLATL LRPADACSCS PVHPQQAFCN ADVVIRAKAV SEKEVDSGND  60
   61 IYGNPIKRIQ YEIKQIKMFK GPDKDIEFIY TAPSSAVCGV SLDVGGKKEY LIAGKAEGDG 120
  121 KMHITLCDFI VPWDTLSITQ KKSLNHRYQM GCECKITRCP MIPCYISSPD ECLWMDWVTE 180
  181 KSINGHQAKF FACIKRSDGS CAWYRGAAPP KQEFLDIEDP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..220] PSI-BLAST 94.221849 HUMAN TISSUE INHIBITOR OF METALLOPROTEINASE-2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • metalloendopeptidase inhibitor activity
    		•  7.17434748400899 bayes_pls_golite062009
  • metalloenzyme regulator activity
    		•  7.17434748400899 bayes_pls_golite062009
  • metalloenzyme inhibitor activity
    		•  7.17434748400899 bayes_pls_golite062009
  • peptidase inhibitor activity
    		•  3.93668549411033 bayes_pls_golite062009
  • endopeptidase inhibitor activity
    		•  3.90361447859652 bayes_pls_golite062009
  • enzyme regulator activity
    		•  2.05189175806105 bayes_pls_golite062009
  • protein binding
    		•  2.04187591727985 bayes_pls_golite062009
  • receptor binding
    		•  1.79096938850925 bayes_pls_golite062009
  • cytokine activity
    		•  1.72828967672993 bayes_pls_golite062009
  • binding
    		•  1.57363735103063 bayes_pls_golite062009
  • enzyme inhibitor activity
    		•  1.54714635439345 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  0.6932827058439 bayes_pls_golite062009
  • chemokine activity
    		•  0.59253057522745 bayes_pls_golite062009
  • chemokine receptor binding
    		•  0.59253057522745 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle