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Protein Overview: unc-44

General Information:
Name(s) found: unc-44 / CE37695 [WormBase]
Description(s) found:
Found 15 descriptions.
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  • WBGene00006780 locus:unc-44 status:Confirmed UniProt:Q5TYL5 protein_id:CCD61796.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 795 amino acids

    Gene Ontology:
    Cellular Component: lateral plasma membrane [IDALink to PubMed article]
    proteinaceous extracellular matrix [IEALink to PubMed article]
    Biological Process: carbohydrate metabolic process [IEALink to PubMed article]
    locomotory behavior [IMPLink to PubMed article]
    signal transduction [IEALink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    cell adhesion [IEALink to PubMed article]
    blood coagulation [IEALink to PubMed article]
    positive regulation of multicellular organism growth [IMPLink to PubMed article]
    positive regulation of locomotion [IMPLink to PubMed article]
    Molecular Function: protein binding [IEALink to PubMed article]
    hydrolase activity, hydrolyzing O-glycosyl compounds [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGCRHSGVR IIVPPRKASQ PIRVTCRYLR KDKLAHPPPL SEGEELASRI LEMAPAGAKF  60
   61 LGPVILEVPH FASLRDRERE IVILRSDDGQ HWKEHQLEAT EDAVQEVLNE SFDAEDLAQL 120
  121 DDLQTPRITR ILTSDFPMYF AVVTRVRQEV HCVGPEGGVI ISSVVPRVQA IFPDGSLTKT 180
  181 IKVSVQAQPV PQEMVTRLHG NRVAVSPIVT VEPRRRKFHK PITLCIPLPQ SNNRGMLTQY 240
  241 SGQQGQEPPT LRLLCSITGG SAPAQWEDIT GTTQLTFTGD EVSFTTTVSA RFWLMDCQTP 300
  301 RDAARMAQEV YNEAISIPYM AKFAVFARRT FPVEGQLRVF CMTDDKEDKT LEKQEHFKLI 360
  361 AKSRDVEVLK GKHQFLEFSG NLVPITKSGD QLSLFFLPFQ ENRLAFMVKT RSNDDNEAAT 420
  421 EGRIGFMAEP KIRSDALPPQ QPICTLAISL PEYTGEIKTA PPPKKDLTPF EQRYGSALEK 480
  481 DLPEFVHQNV LKGIGADWPR LGRALEVPHR DIQHIRQNYP GQECKNTLKI WIHLKKEDAN 540
  541 QDNLDQALRQ IGRDDIVRSI AYGEPDALIN YSQADSPSQK REPIRHFEEV PAATLVKREV 600
  601 RTEDLVTREP VQPTHHVEQA TTVVQEPSYS APVHHSPVPE EPEMEEEAPV AEMRTVVRTE 660
  661 RHVHDSEDGP VVEERTITTT YEDDVAVNEN IVDRTVPLNE DEQQKWEELN RLADESSPSP 720
  721 AQRSTIVAES TSEQVPEDVE QSVESESHRE DDGTIVTTTV TTSHISESPS GSPTRRSVEP 780
  781 EEHRHSQHED HEGST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..87] Pfam 48.49485 No description for PF00791.11 was found. No confident structure predictions are available.
    2 View Details [88..190] deduced N/A No confident structure predictions are available.
    3 View Details [191..400] MSA 2.04793 View MSA. No confident structure predictions are available.
    4 View Details [401..467] deduced N/A No confident structure predictions are available.
    5 View Details [468..591] FFAS03 2.22 FAS DEATH DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE
    6 View Details [592..795] MSA 8.250997 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • binding
    		•  2.68614941294654 bayes_pls_golite062009
  • protein binding
    		•  2.15754892228292 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  1.41916116236037 bayes_pls_golite062009
  • receptor activity
    		•  1.39541116892971 bayes_pls_golite062009
  • signal transducer activity
    		•  1.16091953151708 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.16091953151708 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.398139770818158 bayes_pls_golite062009
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle