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Protein Overview: klar-PB

General Information:
Name(s) found: klar-PB / FBpp0110115 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • The gene klarsicht is referred to in FlyBase by the symbol Dmel\klar (CG17046, FBgn0001316). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:434258..540589. It has the cytological map location 61C1-61C3. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: lipid particle transport along microtubule; tube morphogenesis; compound eye photoreceptor development; lipid transport; membrane organization; nuclear migration; lumen formation, open tracheal system; compound eye morphogenesis. 82 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: external compound sense organ; peripheral nervous system; nervous system; compound cell cluster organ; organ system; rhabdomere; egg; imaginal precursor; cytoplasmic part; cell part. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 2045 amino acids

    Gene Ontology:
    Cellular Component: nuclear envelope [IDA]
    lipid particle [IDA]
    perinuclear region of cytoplasm [IDA]
    cytoplasm [IDA]
    dynein complex [ISS]
    integral to membrane [IEA]
    cytoplasmic microtubule [IDA]
    Biological Process: lipid transport [IMP]
    compound eye photoreceptor development [IMP]
    compound eye morphogenesis [IMP]
    nuclear migration [IMP]
    tube morphogenesis [IMP]
    cellular membrane organization [IMP]
    microtubule-based movement [ISS]
    lipid particle transport along microtubule [IMP]
    lumen formation, open tracheal system [IMP]
    Molecular Function: protein binding [IPI]
    actin binding [IEA]
    ATPase activity, coupled [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEMQQENETG REGVIPNSEK EVALISNQET EKAAMISGGK EGSVRDLESP NETATTQKIE  60
   61 HTTKPLKLDG IFAMPATPPN RAGLTTKSAS SSRSSSLKKQ RRGSRGSANL NVAGTGDGAP 120
  121 KRSAPGGGQL NYGTNSVGND LMKQSQSMTS LKASNEEQQE SRDVIQAKLH LERPYNSLKK 180
  181 NSHSNKMHRY SWGSGNSQCS STSLHSSATL GLGSSGKDDL WAAIQTNYNY IMDTNLLDTC 240
  241 KEARCEIEGA ATVLEKSSEC SFKMLDETQR PEGLCEDPKE LRRWLREMEN KLESSPTITE 300
  301 LTLFGNAELQ RHLAVHSVLY HEIASHARVV SSCIRAAEKE QQLQQQQQLS SQQPASLTSN 360
  361 CSSESTSESA TKSSSLSSGF ASDPVTTPIG TAAAAPPSSS THPSKKGEGN LERLRDRYHL 420
  421 LYLKAFELQL CLDNLLRKRS SAANGLDDDE DEEEDTEDDS FGYEGEATED DLNEVNSDLD 480
  481 LENSESKSAT PAELILQRCQ IAATQIVCGL DETQSQSRSQ QVPSQAKSPS ADQPRDCLAP 540
  541 QKILKSADAS TDDDDEGWLY TATAAATLEV ATAATAAPTA AAATSSVDGL QSTAVSSTTA 600
  601 TGGPLPPSDD SDKENKVALV SATTITAAAT ATATSIATLH SSNYDSSSAC SSSNSNSNSN 660
  661 SNSNGRLTET SATSRVTQLQ MQIHSQSQSQ SQMELQINGN AIDGRHIISN NNCYSSMQHQ 720
  721 PQNNNEGEAA EDLAKIKMGD DEAAADMANG NATKSQQMSN GVYSRADSCN FTVWAAETVA 780
  781 SCHLPPRSPA KSAKSSKSQA SNATVSGSTL VSPVKGKVSH DSIKQLVLEA EHLVRDAQET 840
  841 ALKTPTKQKH SIIKISSTVK KREVTMPHPI KQRVEEWLEH QPSTPQLLTR SHTHELLPSC 900
  901 KPDDCEASGE ASETDSVPQA GAGVNGGAPN GAGSDTSEGF TDSIATCMQT STNSYGNSTE 960
  961 RIGGSAEPIG QPVTPLGFGS SNQSLNVKIV KRSQTRRKSE RPWSVSCLSQ LTTDAAQLTT1020
 1021 ARIVENSPSG LASHSISESA LDSLSPGPRP RAASSSGTGS NAAKKADSKG SLRRRKARKK1080
 1081 RISAASAGRK SDSGSELGGD LTQTLMKSCE SMSSQQLQEF TNALLSIQKG AVVAPLSPKG1140
 1141 DVSGVPSLAD GEGGETQLML PKFRVGSFTT AGLLATDTRL GALAALSNYM NEDEQQAELS1200
 1201 TEDHHSSISE TAWDNYQEKY NSENYSEGFD SDAARRLLEF GDDYRNFIDS QSDCCSSLSA1260
 1261 ANNLDSFSPP RMDSLQKHEL KTLHINQDTI TSTVDHARRQ RALELQYERR RKTLEVRRKS1320
 1321 CQDMDESLMA SPQSDQQQQQ LQVTPSLSAS ATALMTTPKI QSTSHQISHR AESVGRKLDF1380
 1381 GGMSHSAQSL LRRTSESDTS TRRRRTVTAD ERRRSSRNLE KCIKLIPATT SSSSGSDSED1440
 1441 GEQEMRSLLQ QSRDRLDDTR ALKIRCHLLR PEDYNEIINT CRDNIRCLEA VLRGPPGTVL1500
 1501 SNHCAGQTKD LLGAWEDLLS WSENASAARK LQQEMSVLKS SLQRLGDKPT PELLDTEPAI1560
 1561 QIAVEALKLE QTQLTSYRTN MLRLNASVHS WLTKQERRLQ SALEEQEQQQ ESEQLKQQKL1620
 1621 VEEEKGADVQ KELASTGAVA ITVTDSNGNQ VEALATGEAS TSTPAWDVHT LMSSEQEFHK1680
 1681 HLKNEVSDMY SSWDEADARI NTQLEMLTNS LIAWRQLESG LSEFQLALGQ DRGTLKGLEG1740
 1741 ALDKGQATPV ELAQNVKLVA KLLSEKVHVS QEQLLAVQQH LDPNHIYHIT KFTASNGSLS1800
 1801 DSGISDGGAT SDGGLSERER RLGVLRRLAK QLELALAPGS EAMRSIAARM ESAEADLKHL1860
 1861 QNTCRDLIVR TAASHQQKQQ IQQNQTQQVS PKANGHIKKQ AAKGKAEPQS PGRRGKGARK1920
 1921 ARQAKKAGED QQVEEPSLSP EQQKMVLKQL KTLTSGDGGD DPSDDPSLLF NLESSEEDGE1980
 1981 GADPAQTSKR GWAWRIARAA VPMQVALFTI FCAACLMQPN CCDNLNNLSM SFTPQLRYIR2040
 2041 GPPPI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle