Protein Overview: gi|30259099, gi|...

General Information:
Name(s) found:	gi\|30264441 [NCBI NR] gi\|30259099 [NCBI NR]
Description(s) found: Found 4 descriptions. SHOW ALL	gi\|30264441\|ref\|NP_846818.1\| bifunctional acetaldehyde-CoA/alcohol dehydrogenase [Bacillus anthracis str. Ames] [NCBI NR] gi\|30259099\|gb\|AAP28304.1\| aldehyde-alcohol dehydrogenase [Bacillus anthracis str. Ames] [NCBI NR]
Organism:	Bacillus anthracis str. Ames
Length:	867 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	fermentation [ISS]
Molecular Function:	3-chloroallyl aldehyde dehydrogenase activity [ISS] alcohol dehydrogenase activity, iron-dependent [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVKEKVVNE MQEVKEMIDT LVNNGRKALQ ALESFTQEQI DNIVHEMALA GVDQHMPLAK  60
   61 LAVEETGRGV YEDKCIKNIF ATEYIWHSIK KDKTVGIIHE DPHEEIIEIA EPVGVVAGVT 120
  121 PVTNPTSTTM FKALIAIKTR NPIIFAFHPS AQNCSVAAAK TVYDAAVKAG APKHCIQWIE 180
  181 KPSVEATKQL MNHEGVALVL ATGGAGMVKS AYSTGKPALG VGPGNVPCYI EKSAHIKRAV 240
  241 NDLILSKTFD NGMICASEQA IIVDKEIYDD VKTEMITNDC YFVTEEERRK LEKLVINENT 300
  301 CAVNSDIVGK SAQYIAELVG ITVPKNTKML VAEIQGIGAA YPLSREKLSP VLACVKANSL 360
  361 EEGFTYCEEM LNLGGLGHSA VIHSVNKEVQ KQFGLRMKAC RLIVNAPSSQ GGIGDIYNGF 420
  421 IPSLTLGCGS YGKNSVSQNV TATHLLNIKR LANRKKNMQW FKLPPKIYFE KHATAYLANM 480
  481 PNISRAFIVT DPGMVEHGYV DTVAHYLRKH ANDVKVEVFF EVEPDPSDET VFKGAEMMRS 540
  541 FQPDVIIALG GGSAMDAAKG MWLFYEYPET TFYGIKQKFL DIRKRTCKYP ELGSKAQFVA 600
  601 IPTTSGTGSE VTPFAVITDK KNNIKYPLAD YELTPDVAIV DPQFVMTVPP HVTADTGMDV 660
  661 LTHAIEAYVS VLANDYTDGL ALKAIDLVFK YLPRAFKDGH DEEAREKMHN ASAIAGMAFA 720
  721 NAFLGINHSL AHKIGPEFHI PHGRANAILM PHVIRYNAIK PRKHALFPKY EHFVADERYA 780
  781 HIARMLGLPA SSVAEGVESL DKAIIDLGKS LNINMSIAGQ GVAKDQFEEV VGLLAERAFE 840
  841 DQCTTANPKL PLISELKEIY MKAYKGE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..455]	PSI-BLAST	139.0	Aldehyde reductase (dehydrogenase), ALDH
2	View Details	[456..867]	PSI-BLAST	91.30103	Crystal Structure of Lactaldehyde reductase

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
oxidoreductase activity	4.47226217021998	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	4.34495776828926	bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity	3.37049090049734	bayes_pls_golite062009
succinate-semialdehyde dehydrogenase [NAD(P)+] activity	3.30681232755737	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	3.2867555127991	bayes_pls_golite062009
aldehyde dehydrogenase (NAD) activity	2.81851373615334	bayes_pls_golite062009
catalytic activity	2.80804701752928	bayes_pls_golite062009
succinate-semialdehyde dehydrogenase activity	2.25908515251731	bayes_pls_golite062009
benzaldehyde dehydrogenase activity	1.80313175632526	bayes_pls_golite062009
methylmalonate-semialdehyde dehydrogenase (acylating) activity	1.59279206536309	bayes_pls_golite062009
1-pyrroline-5-carboxylate dehydrogenase activity	1.15620590715864	bayes_pls_golite062009
binding	0.637403449596354	bayes_pls_golite062009

2

Term	Confidence	Notes
hydroxyacid-oxoacid transhydrogenase activity	8.51876704052427	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	5.26400058766942	bayes_pls_golite062009
oxidoreductase activity	3.07409531087588	bayes_pls_golite062009
alcohol dehydrogenase activity, metal ion-independent	3.05722501802075	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	2.83823088483915	bayes_pls_golite062009
catalytic activity	2.37357608468991	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2.10085302216488	bayes_pls_golite062009
binding	1.15096180564234	bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity	0.831155115586418	bayes_pls_golite062009
cation binding	0.319000821544479	bayes_pls_golite062009
metal ion binding	0.319000821544479	bayes_pls_golite062009
ion binding	0.313606245452103	bayes_pls_golite062009
protein binding	0.295023706645045	bayes_pls_golite062009
transition metal ion binding	0.259889634539407	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.0904828025133766	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle