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Protein Overview: LEPA_LISMO

General Information:
Name(s) found: LEPA_LISMO [Swiss-Prot]
Description(s) found:
Found 5 descriptions.
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  • Elongation factor 4 OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=lepA PE=3 SV=1 [Swiss-Prot]
    • Organism: Listeria monocytogenes EGD-e
    Length: 608 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKEEMNARQ KKIRNFSIIA HIDHGKSTLA DRILEQTGAL THREMKNQLL DSMDLERERG  60
   61 ITIKLNAVQL KYKAKDGETY IFHLIDTPGH VDFTYEVSRS LAACEGAILV VDAAQGIEAQ 120
  121 TLANVYLALD NDLEILPVIN KIDLPAADPE RVREEIEDVI GLDASDAVLA SAKSGIGIED 180
  181 ILEQIVEKVP EPSGDVNKPL KALIFDSVFD AYRGVIANIR IMDGVVKAGD RIKMMSNGKE 240
  241 FEVTEVGVFS PKATPRDELL VGDVGYLTAA IKNVGDTRVG DTITLANNPA EEALDGYRKL 300
  301 NPMVYCGLYP IDSSKYNDLR DALEKLELND SALQFEAETS QALGFGFRCG FLGLLHMEII 360
  361 QERIEREFNI DLITTAPSVI YHVNLTDGSN IVVDNPAEMP EPGVIESVEE PYVKATVMVP 420
  421 NDYVGAVMEL AQNKRGNFIT MEYLDDIRVS IVYEIPLSEI VYDFFDQLKS STKGYASFDY 480
  481 ELIGYKASKL VKMDILLNAE KVDALSFIVH RDFAYERGKI IVEKLKELIP RQQFEVPIQA 540
  541 AIATKIVSRS TIKALRKNVL AKCYGGDVSR KRKLLEKQKE GKKRMKQIGS VEVPQEAFMA 600
  601 ILKMDESK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..91] PSI-BLAST 59.522879 Elongation factor eEF-1alpha, domain 2; Elongation factor eEF-1alpha, C-terminal domain; Elongation factor eEF-1alpha, N-terminal (G) domain
    2 View Details [92..188] FFAS03 3.76 Initiation factor IF2/eIF5b, domains 2 and 4; Initiation factor IF2/eIF5b, domain 3; Initiation factor IF2/eIF5b, N-terminal (G) domain
    3 View Details [189..608] PSI-BLAST 55.09691 Ribosomal elongation factor G (EF-G) Fusidic acid resistant mutant T84A.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • structural constituent of ribosome
    		•  4.57470667789966 bayes_pls_golite062009
  • structural molecule activity
    		•  3.66323426032744 bayes_pls_golite062009
  • translation elongation factor activity
    		•  3.16158345572509 bayes_pls_golite062009
  • binding
    		•  2.15223415484989 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.50098700711558 bayes_pls_golite062009
  • protein binding
    		•  1.25232424749674 bayes_pls_golite062009
  • DNA binding
    		•  1.19194387475416 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.12203014375349 bayes_pls_golite062009
  • catalytic activity
    		•  0.942640875796745 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.354154818458687 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.35085688811866 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.350844329183388 bayes_pls_golite062009
  • nucleotide binding
    		•  0.350227693353399 bayes_pls_golite062009
  • transcription activator activity
    		•  0.171881962521773 bayes_pls_golite062009
  • translation regulator activity
    		•  0.165004576559811 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.144513585153713 bayes_pls_golite062009
  • RNA binding
    		•  0.10404338295854 bayes_pls_golite062009
  • transcription factor activity
    		•  0.101575043176033 bayes_pls_golite062009
  • mRNA binding
    		•  0.0213504428103857 bayes_pls_golite062009
    3
    Term Confidence Notes
  • structural constituent of ribosome
    		•  6.48160314495408 bayes_pls_golite062009
  • structural molecule activity
    		•  5.89785955477588 bayes_pls_golite062009
  • translation initiation factor activity
    		•  2.68619850021832 bayes_pls_golite062009
  • peptidyltransferase activity
    		•  2.36235718442873 bayes_pls_golite062009
  • translation elongation factor activity
    		•  1.78840251801545 bayes_pls_golite062009
  • mRNA binding
    		•  1.64128426760439 bayes_pls_golite062009
  • RNA binding
    		•  1.40868766468494 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.30900892230008 bayes_pls_golite062009
  • protein binding
    		•  1.24158964059466 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.17107716081138 bayes_pls_golite062009
  • binding
    		•  1.0709940954148 bayes_pls_golite062009
  • DNA binding
    		•  0.911272650085046 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • transcription activator activity
    		•  0.491297187941564 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.19921800066954 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.180372638853914 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  6.9430052008157E-5 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle