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Protein Overview: FOLD2_GEOSL

General Information:
Name(s) found: FOLD2_GEOSL [Swiss-Prot]
Description(s) found:
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  • gi|39995968|ref|NP_951919.1| folD bifunctional protein [Geobacter sulfurreducens PCA] [NCBI NR]
  • gi|39982733|gb|AAR34192.1| folD bifunctional protein [Geobacter sulfurreducens PCA] [NCBI NR]
  • Bifunctional protein FolD 2 OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) GN=folD2 PE=3 SV=1 [Swiss-Prot]
  • folD bifunctional protein [Geobacter sulfurreducens PCA]gi|39982733|gb|AAR34192.1| folD bifunctional protein [Geobacter sulfurreducens PCA] [nrdb_11152004_Chlamydomonas]
  • folD bifunctional protein [Geobacter sulfurreducens PCA] [nr-271106-contam.fasta]
    • Organism: Geobacter sulfurreducens PCA
    Length: 285 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: methionine biosynthetic process [ISSLink to PubMed article]
    pantothenate biosynthetic process [ISSLink to PubMed article]
    10-formyltetrahydrofolate biosynthetic process [ISSLink to PubMed article]
    histidine biosynthetic process [ISSLink to PubMed article]
    purine base biosynthetic process [ISSLink to PubMed article]
    Molecular Function: methylenetetrahydrofolate dehydrogenase activity [ISSLink to PubMed article]
    methenyltetrahydrofolate cyclohydrolase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATIIDGKAI AEKIRADLAA QVKELQSRGI TPGLATVLVG SDPASEVYVR MKGDACNKLG  60
   61 MHSVKITRPA ETTEEELLAL INELNNDPAI HGILVQLPLP PQINADRVLE AISPAKDVDG 120
  121 FHPYNVGRLV TGKPTFQPCT PYGVMVMLQE AGVDLAGKEV VVVGRSNIVG KPVALMCLQR 180
  181 NATVTICHSK TRDLPGRVRA ADVVIAAVGV PEMIKGDWIK EGAVVIDVGV NRVGEKKLVG 240
  241 DVEFAAAAER ASAITPVPGG VGPMTITMLL HNTLEAAKMA GSGNR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..285] PSI-BLAST 111.0 Methylenetetrahydrofolate dehydrogenase/cyclohydrolase; Tetrahydrofolate dehydrogenase/cyclohydrolase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity
    		•  3.54983447672782 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.66605122152932 bayes_pls_golite062009
  • malate dehydrogenase activity
    		•  2.43636049081724 bayes_pls_golite062009
  • catalytic activity
    		•  2.0643953589843 bayes_pls_golite062009
  • methenyltetrahydrofolate cyclohydrolase activity
    		•  1.95551536198286 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.54527841865655 bayes_pls_golite062009
  • malic enzyme activity
    		•  1.39067036188188 bayes_pls_golite062009
  • binding
    		•  1.14588824263074 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
    		•  0.66392365734856 bayes_pls_golite062009
  • cyclohydrolase activity
    		•  0.129148522173579 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle