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Protein Overview: FOLD1_GEOSL

General Information:
Name(s) found: FOLD1_GEOSL [Swiss-Prot]
Description(s) found:
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  • gi|39995325|ref|NP_951276.1| folD bifunctional protein [Geobacter sulfurreducens PCA] [NCBI NR]
  • gi|39982087|gb|AAR33549.1| folD bifunctional protein [Geobacter sulfurreducens PCA] [NCBI NR]
  • Bifunctional protein FolD 1 OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) GN=folD1 PE=3 SV=1 [Swiss-Prot]
  • folD bifunctional protein [Geobacter sulfurreducens PCA]gi|39982087|gb|AAR33549.1| folD bifunctional protein [Geobacter sulfurreducens PCA] [nrdb_11152004_Chlamydomonas]
  • folD bifunctional protein [Geobacter sulfurreducens PCA] [nr-271106-contam.fasta]
    • Organism: Geobacter sulfurreducens PCA
    Length: 290 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: methionine biosynthetic process [ISSLink to PubMed article]
    pantothenate biosynthetic process [ISSLink to PubMed article]
    10-formyltetrahydrofolate biosynthetic process [ISSLink to PubMed article]
    histidine biosynthetic process [ISSLink to PubMed article]
    purine base biosynthetic process [ISSLink to PubMed article]
    Molecular Function: methylenetetrahydrofolate dehydrogenase activity [ISSLink to PubMed article]
    methenyltetrahydrofolate cyclohydrolase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLLDGKKCA ESLVAEIARK VAGYTESGLR TPHMTIILVG EHAPSESYVK SKIATSGLAG  60
   61 FESTLLRFPE TIRESELLAK IKEVNEDPTT DGLIVQLPLP KHINQQHVIN AIAPEKDIDG 120
  121 FHPANFGRMT LGQKAFRPAT AYGICKLLQF YEVPVKAKHC VVIGRSNIVG KPISIMLSND 180
  181 FDIGNATVTL THIETPRELL LDETRRADIV IVAVGIPGFV TADMVKDGVV LIDVGINRLE 240
  241 SGKIVGDVDF ENVAQKCSWI TPVPGGVGRM TVAALMINTL MAYQNNFNLA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..290] PSI-BLAST 116.0 Methylenetetrahydrofolate dehydrogenase/cyclohydrolase; Tetrahydrofolate dehydrogenase/cyclohydrolase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity
    		•  3.54983447672782 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.66605122152932 bayes_pls_golite062009
  • malate dehydrogenase activity
    		•  2.43636049081724 bayes_pls_golite062009
  • catalytic activity
    		•  2.0643953589843 bayes_pls_golite062009
  • methenyltetrahydrofolate cyclohydrolase activity
    		•  1.95551536198286 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.54527841865655 bayes_pls_golite062009
  • malic enzyme activity
    		•  1.39067036188188 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.36004762962019 bayes_pls_golite062009
  • binding
    		•  1.14588824263074 bayes_pls_golite062009
  • DNA binding
    		•  1.10991625623485 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.889110653819813 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
    		•  0.66392365734856 bayes_pls_golite062009
  • transcription factor activity
    		•  0.447125343834924 bayes_pls_golite062009
  • cyclohydrolase activity
    		•  0.129148522173579 bayes_pls_golite062009
  • ligase activity
    		•  0.0191278372003161 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle