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Protein Overview: HGNC:8794|MIM:60...

General Information:
Name(s) found: HGNC:8794|MIM:603390|Ensembl:ENSG00000113231|HPRD:04546,HsxXG003541,C04,HsCD00302972,470529.0,pANT7_cGST,FUSION,NM_003719,8622.0,PDE8B,ADSD|FLJ11212|PPNAD3,phosphodiesterase [120926-122011-mus-fusion.fasta]
Description(s) found:
  • 8B [120926-122011-mus-fusion.fasta]
    • Organism: SPECIES UNKNOWN
    Length: 885 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGCAPSIHVS QSGVIYCRDS DESSSPRQTT SVSQGPAAPL PGLFVQTDAA DAIPPSRASG  60
   61 PPSVARVRRA RTELGSGSSA GSAAPAATTS RGRRRHCCSS AEAETQTCYT SVKQVSSAEV 120
  121 RIGPMRLTQD PIQVLLIFAK EDSQSDGFWW ACDRAGYRCN IARTPESALE CFLDKHHEII 180
  181 VIDHRQTQNF DAEAVCRSIR ATNPSEHTVI LAVVSRVSDD HEEASVLPLL HAGFNRRFME 240
  241 NSSIIACYNE LIQIEHGEVR SQFKLRACNS VFTALDHCHE AIEITSDDHV IQYVNPAFER 300
  301 MMGYHKGELL GKELADLPKS DKNRADLLDT INTCIKKGKE WQGVYYARRK SGDSIQQHVK 360
  361 ITPVIGQGGK IRHFVSLKKL CCTTDNNKQI HKIHRDSGDN SQTEPHSFRY KNRRKESIDV 420
  421 KSISSRGSDA PSLQNRRYPS MARIHSMTIE APITKVINII NAAQENSPVT VAEALDRVLE 480
  481 ILRTTELYSP QLGTKDEDPH TSDLVGGLMT DGLRRLSGNE YVFTKNVHQS HSHLAMPITI 540
  541 NDVPPCISQL LDNEESWDFN IFELEAITHK RPLVYLGLKV FSRFGVCEFL NCSETTLRAW 600
  601 FQVIEANYHS SNAYHNSTHA ADVLHATAFF LGKERVKGSL DQLDEVAALI AATVHDVDHP 660
  661 GRTNSFLCNA GSELAVLYND TAVLESHHTA LAFQLTVKDT KCNIFKNIDR NHYRTLRQAI 720
  721 IDMVLATEMT KHFEHVNKFV NSINKPMAAE IEGSDCECNP AGKNFPENQI LIKRMMIKCA 780
  781 DVANPCRPLD LCIEWAGRIS EEYFAQTDEE KRQGLPVVMP VFDRNTCSIP KSQISFIDYF 840
  841 ITDMFDAWDA FAHLPALMQH LADNYKHWKT LDDLKCKSLR LPSDS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..108] PSI-BLAST 15.522879 Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
    2 View Details [109..394] PSI-BLAST 9.69897 No description for 2gwrA was found.
    3 View Details [395..499] deduced N/A No confident structure predictions are available.
    4 View Details [500..885] PSI-BLAST 113.0 Catalytic domain of cyclic nucleotide phosphodiesterase pde4d

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • 3',5'-cyclic-nucleotide phosphodiesterase activity
    		•  4.72905094107626 bayes_pls_golite062009
  • cyclic-nucleotide phosphodiesterase activity
    		•  4.61245226349897 bayes_pls_golite062009
  • phosphoric diester hydrolase activity
    		•  3.65984874547256 bayes_pls_golite062009
  • 3',5'-cyclic-AMP phosphodiesterase activity
    		•  3.3591603098704 bayes_pls_golite062009
  • 3',5'-cyclic-GMP phosphodiesterase activity
    		•  2.96981753811593 bayes_pls_golite062009
  • hydrolase activity
    		•  1.22736412056595 bayes_pls_golite062009
  • catalytic activity
    		•  1.07048165010262 bayes_pls_golite062009
  • binding
    		•  0.994379083280533 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.511207383357891 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.432240759268351 bayes_pls_golite062009
  • protein binding
    		•  0.162314119157812 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle