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Protein Overview: HGNC:4118|MIM:60...

General Information:
Name(s) found: HGNC:4118|MIM:604313|Ensembl:ENSG00000108479|HPRD:05057,HsxXG002361,B05,HsCD00298721,230868.0,pLDNT7_nFLAG,CLOSED,BC001166,2584.0,GALK1,GALK|GK1,galactokinase [120926-122011-mus-fusion.fasta]
Description(s) found:
  • 1 [120926-122011-mus-fusion.fasta]
    • Organism: SPECIES UNKNOWN
    Length: 392 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAALRQPQVA ELLAEARRAF REEFGAEPEL AVSAPGRVNL IGEHTDYNQG LVLPMALELM  60
   61 TVLVGSPRKD GLVSLLTTSE GADEPQRLQF PLPTAQRSLE PGTPRWANYV KGVIQYYPAA 120
  121 PLPGFSAVVV SSVPLGGGLS SSASLEVATY TFLQQLCPDS GTIAARAQVC QQAEHSFAGM 180
  181 PCGIMDQFIS LMGQKGHALL IDCRSLETSL VPLSDPKLAV LITNSNVRHS LASSEYPVRR 240
  241 RQCEEVARAL GKESLREVQL EELEAARDLV SKEGFRRARH VVGEIRRTAQ AAAALRRGDY 300
  301 RAFGRLMVES HRSLRDDYEV SCPELDQLVE AALAVPGVYG SRMTGGGFGG CTVTLLEASA 360
  361 APHAMRHIQE HYGGTATFYL SQAADGAKVL CL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..392] PSI-BLAST 97.154902 crystal structure of human galactokinase complexed with MgAMPPNP and galactose

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  2.57444343595083 bayes_pls_golite062009
  • kinase activity
    		•  2.45533953107206 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.15678581504347 bayes_pls_golite062009
  • galactokinase activity
    		•  1.98579505313408 bayes_pls_golite062009
  • transferase activity
    		•  1.44847475955289 bayes_pls_golite062009
  • galactose binding
    		•  1.09822999475915 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.861708516886368 bayes_pls_golite062009
  • catalytic activity
    		•  0.836142537655721 bayes_pls_golite062009
  • binding
    		•  0.81933081762145 bayes_pls_golite062009
  • nuclease activity
    		•  0.750627453499812 bayes_pls_golite062009
  • hydrolase activity
    		•  0.740929677099368 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  0.29372632468704 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.268974873769861 bayes_pls_golite062009
  • protein binding
    		•  0.252740644591197 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.24527927280502 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  0.236567582613739 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.168901349358066 bayes_pls_golite062009
  • peptidase activity
    		•  0.14842914604274 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle