Protein Overview: LEU3_SHEON

General Information:
Name(s) found:	LEU3_SHEON [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|24375719\|ref\|NP_719762.1\| 3-isopropylmalate dehydrogenase [Shewanella oneidensis MR-1] [NCBI NR] gi\|24350655\|gb\|AAN57206.1\|AE015856_6 3-isopropylmalate dehydrogenase [Shewanella oneidensis MR-1] [NCBI NR] 3-isopropylmalate dehydrogenase OS=Shewanella oneidensis (strain MR-1) GN=leuB PE=1 SV=1 [Swiss-Prot] 3-isopropylmalate dehydrogenase [Shewanella oneidensis MR-1]gi\|24350655\|gb\|AAN57206.1\| 3-isopropylmalate dehydrogenase [Shewanella oneidensis MR-1]gi\|39931971\|sp\|Q8E9N3\|LEU3_SHEON 3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH [nrdb_11152004_Chlamydomonas] 3-isopropylmalate dehydrogenase [Shewanella oneidensis MR-1] [nr-271106-contam.fasta]
Organism:	Shewanella oneidensis MR-1
Length:	364 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	leucine biosynthetic process [ISS]
Molecular Function:	3-isopropylmalate dehydrogenase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYQIAVLAG DGIGPEVMAE ARKVLKAVEA RFGLNIEYTE YDVGGIAIDN HGCPLPEATL  60
   61 KGCEAADAIL FGSVGGPKWE KLPPNEQPER GALLPLRGHF ELFCNLRPAK LHDGLEHMSP 120
  121 LRSDISARGF DVLCVRELTG GIYFGKPKGR QGEGESEEAF DTMRYSRREI SRIARIAFEA 180
  181 ARGRRKKVTS VDKANVLACS VLWRQVVEEV AVDFPDVELE HIYIDNATMQ LLRRPDEFDV 240
  241 MLCSNLFGDI LSDEIAMLTG SMGLLSSASM NSTGFGLFEP AGGSAPDIAG KGIANPIAQI 300
  301 LSAALMLRHS LKQEEAASAI ERAVTKALNS GYLTGELLSS DQRHKAKTTV QMGDFIADAV 360
  361 KAGV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

Term	Confidence	Notes
isocitrate dehydrogenase (NAD+) activity	5.9567768649084	bayes_pls_golite062009
isocitrate dehydrogenase activity	5.76817846591752	bayes_pls_golite062009
3-isopropylmalate dehydrogenase activity	4.43187390953534	bayes_pls_golite062009
isocitrate dehydrogenase (NADP+) activity	3.47645456015586	bayes_pls_golite062009
malate dehydrogenase activity	3.17013707624362	bayes_pls_golite062009
oxidoreductase activity	2.74237430402883	bayes_pls_golite062009
catalytic activity	2.71251959637136	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	2.46799258909805	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2.38235863668553	bayes_pls_golite062009
binding	1.19820115767498	bayes_pls_golite062009
malic enzyme activity	0.483776792839856	bayes_pls_golite062009
transferase activity, transferring acyl groups	0.466038297142601	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.77

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..364]	PSI-BLAST	137.0	3-isopropylmalate dehydrogenase, IPMDH

Protein Overview: LEU3_SHEON

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: