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Protein Overview: LEU3_SHEON

General Information:
Name(s) found: LEU3_SHEON [Swiss-Prot]
Description(s) found:
Found 5 descriptions.
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  • 3-isopropylmalate dehydrogenase OS=Shewanella oneidensis (strain MR-1) GN=leuB PE=1 SV=1 [Swiss-Prot]
    • Organism: Shewanella oneidensis MR-1
    Length: 364 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: leucine biosynthetic process [ISSLink to PubMed article]
    Molecular Function: 3-isopropylmalate dehydrogenase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYQIAVLAG DGIGPEVMAE ARKVLKAVEA RFGLNIEYTE YDVGGIAIDN HGCPLPEATL  60
   61 KGCEAADAIL FGSVGGPKWE KLPPNEQPER GALLPLRGHF ELFCNLRPAK LHDGLEHMSP 120
  121 LRSDISARGF DVLCVRELTG GIYFGKPKGR QGEGESEEAF DTMRYSRREI SRIARIAFEA 180
  181 ARGRRKKVTS VDKANVLACS VLWRQVVEEV AVDFPDVELE HIYIDNATMQ LLRRPDEFDV 240
  241 MLCSNLFGDI LSDEIAMLTG SMGLLSSASM NSTGFGLFEP AGGSAPDIAG KGIANPIAQI 300
  301 LSAALMLRHS LKQEEAASAI ERAVTKALNS GYLTGELLSS DQRHKAKTTV QMGDFIADAV 360
  361 KAGV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..364] PSI-BLAST 137.0 3-isopropylmalate dehydrogenase, IPMDH

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • isocitrate dehydrogenase (NAD+) activity
    		•  5.9567768649084 bayes_pls_golite062009
  • isocitrate dehydrogenase activity
    		•  5.76817846591752 bayes_pls_golite062009
  • 3-isopropylmalate dehydrogenase activity
    		•  4.43187390953534 bayes_pls_golite062009
  • isocitrate dehydrogenase (NADP+) activity
    		•  3.47645456015586 bayes_pls_golite062009
  • malate dehydrogenase activity
    		•  3.17013707624362 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.74237430402883 bayes_pls_golite062009
  • catalytic activity
    		•  2.71251959637136 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.46799258909805 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  2.38235863668553 bayes_pls_golite062009
  • binding
    		•  1.19820115767498 bayes_pls_golite062009
  • malic enzyme activity
    		•  0.483776792839856 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.466038297142601 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.77

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle