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Protein Overview: gi|24375268, gi|...

General Information:
Name(s) found: gi|24375268 [NCBI NR]
gi|24350070 [NCBI NR]
Description(s) found:
Found 4 descriptions.
SHOW ALL
  • gi|24375268|ref|NP_719311.1| bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase [Shewanella oneidensis MR-1] [NCBI NR]
  • gi|24350070|gb|AAN56755.1|AE015811_3 proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase, putative [Shewanella oneidensis MR-1] [NCBI NR]
    • Organism: Shewanella oneidensis MR-1
    Length: 1059 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: proline catabolic process [ISSLink to PubMed article]
    Molecular Function: 1-pyrroline-5-carboxylate dehydrogenase activity [ISSLink to PubMed article]
    proline dehydrogenase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKASEVLAG RYDSANLDEL FKAVTDNYIV DEEQYLSELI KLVPSSDEAI ERVTRRAHEL  60
   61 VNKVRQFEKK GLMVGIDAFL QQYSLETQEG IILMCLAEAL LRIPDAATAD ALIEDKLSGA 120
  121 KWDEHLSKSD SVLVNASTWG LMLTGKIVSL DKKIDGSSSN LLGRLVNRLG EPVIRQAMMA 180
  181 AMKIMGKQFV LGRTMKEALK NSEDKRKLGY THSYDMLGEA ALTRKDAEKY FTDYANAITE 240
  241 LGAQSYNESE SPRPTISIKL SALHPRYEVA NEDRVLTELY DTVIRLIKLA RGLNIGISID 300
  301 AEEVDRLELS LKLFQKLFNS EATKGWGLLG IVVQAYSKRA LPVLVWLTRL AKEQGDEIPV 360
  361 RLVKGAYWDS ELKWAQQAGE AAYPLYTRKA GTDVSYLACA RYLLSDATRG AIYPQFASHN 420
  421 AQTVAAISDM AGDRNHEFQR LHGMGQELYD TILSEAGAKA VRIYAPIGAH KDLLPYLVRR 480
  481 LLENGANTSF VHKLVDPKTP IESLVVHPLK TLTSYKTLAN NKIVLPIDIF GSDRKNSKGL 540
  541 NMNIISEAEP FFAALDKFKS TQWQAGPLVN GQPLTGEHKT IVSPFDTTQT VGQVAFADKA 600
  601 AIEQAVSSAH AAFGSWTRTP VEVRASALQK LADLLEENRE ELIALCTREA GKSIQDGIDE 660
  661 VREAVDFCRY YAVQAKKLMS KPELLPGPTG ELNELFLQGR GVFVCISPWN FPLAIFLGQV 720
  721 SAALAAGNTV VAKPAEQTSI IGYRAVQLAH QAGIPTDVLQ YLPGTGATVG NALTADERIG 780
  781 GVCFTGSTGT AKLINRTLAN REGAIIPLIA ETGGQNAMVV DSTSQPEQVV NDVVSSSFTS 840
  841 AGQRCSALRV LFLQEDIADR VIDVLQGAMD ELVIGNPSSI KTDVGPVIDA TAKANLDAHI 900
  901 DHIKQVGKLI KQMSLPAGTE NGHFVAPTAV EIDSIKVLEK EHFGPILHVI RYKASELAHV 960
  961 IDEINSTGFG LTLGIHSRNE GHALEVADKV NVGNVYINRN QIGAVVGVQP FGGQGLSGTG1020
 1021 PKAGGPHYLT RFVTEKTRTN NITAIGGNAT LLSLGDSDA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..570] PSI-BLAST 1000.0 N-terminal domain of bifunctional PutA protein; Proline dehydrohenase domain of bifunctional PutA protein
    2 View Details [571..1059] PSI-BLAST 115.0 1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  6.88732579226533 bayes_pls_golite062009
  • 1-pyrroline-5-carboxylate dehydrogenase activity
    		•  6.68550231605226 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
    		•  5.85251457886657 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.26500423104107 bayes_pls_golite062009
  • methylenetetrahydrofolate reductase (NADPH) activity
    		•  3.12501983452885 bayes_pls_golite062009
  • catalytic activity
    		•  2.15527229494088 bayes_pls_golite062009
  • binding
    		•  1.75614413431284 bayes_pls_golite062009
  • protein binding
    		•  1.38007868564575 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.577994923694075 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.464400793583132 bayes_pls_golite062009
  • DNA binding
    		•  0.359090400165996 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.0464200104039556 bayes_pls_golite062009
    2
    Term Confidence Notes
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  5.09598561374689 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.47226217021998 bayes_pls_golite062009
  • 1-pyrroline-5-carboxylate dehydrogenase activity
    		•  4.35175408702761 bayes_pls_golite062009
  • methylmalonate-semialdehyde dehydrogenase (acylating) activity
    		•  3.87605237828483 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase [NAD(P)+] activity
    		•  3.64672165191647 bayes_pls_golite062009
  • 3-chloroallyl aldehyde dehydrogenase activity
    		•  3.37049090049734 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  3.2867555127991 bayes_pls_golite062009
  • glutamate-5-semialdehyde dehydrogenase activity
    		•  3.27180265380824 bayes_pls_golite062009
  • benzaldehyde dehydrogenase activity
    		•  2.99564252244797 bayes_pls_golite062009
  • aldehyde dehydrogenase (NAD) activity
    		•  2.81851373615334 bayes_pls_golite062009
  • catalytic activity
    		•  2.80804701752928 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase activity
    		•  2.71501590413507 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  2.70230501280821 bayes_pls_golite062009
  • aldehyde dehydrogenase [NAD(P)+] activity
    		•  2.43250909158896 bayes_pls_golite062009
  • aminobutyraldehyde dehydrogenase activity
    		•  2.35958138496479 bayes_pls_golite062009
  • malonate-semialdehyde dehydrogenase (acetylating) activity
    		•  1.75951883819887 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
    		•  1.6559690223037 bayes_pls_golite062009
  • retinal dehydrogenase activity
    		•  1.42867174920845 bayes_pls_golite062009
  • electron carrier activity
    		•  1.33390667257376 bayes_pls_golite062009
  • binding
    		•  1.06673666884196 bayes_pls_golite062009
  • retinoid binding
    		•  0.983782635681687 bayes_pls_golite062009
  • isoprenoid binding
    		•  0.900374761028287 bayes_pls_golite062009
  • protein binding
    		•  0.894945263794726 bayes_pls_golite062009
  • hydrolase activity
    		•  0.799513645745266 bayes_pls_golite062009
  • histidinol dehydrogenase activity
    		•  0.258030369394064 bayes_pls_golite062009
  • benzaldehyde dehydrogenase (NAD+) activity
    		•  0.23487570676521 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle