Protein Overview: gi|24348056, gi|...

General Information:
Name(s) found:	gi\|24373696 [NCBI NR] gi\|24348056 [NCBI NR]
Description(s) found: Found 4 descriptions. SHOW ALL	gi\|24373696\|ref\|NP_717739.1\| bifunctional acetaldehyde-CoA/alcohol dehydrogenase [Shewanella oneidensis MR-1] [NCBI NR] gi\|24348056\|gb\|AAN55183.1\|AE015655_9 aldehyde-alcohol dehydrogenase [Shewanella oneidensis MR-1] [NCBI NR]
Organism:	Shewanella oneidensis MR-1
Length:	866 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	fermentation [ISS]
Molecular Function:	3-chloroallyl aldehyde dehydrogenase activity [ISS] iron ion binding [ISS] alcohol dehydrogenase activity, iron-dependent [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVTNAQKLD LMVERVARAQ AEYASFSQAQ VDAIFRAAAL AAADARISLA KMAAAETRMG  60
   61 VIEDKVIKNH FASEYIYNKY KDEKTCGILS EDPTFGTITI AEPVGIICGI VPTTNPTSTA 120
  121 IFKALISLKT RNAIIFSPHP RAKVSTTTAA KLVLDAAIAA GAPKDIIGWI DEPSVALSNQ 180
  181 LMTHPKVNLI LATGGPGMVK AAYSSGKPAI GVGAGNTPIV IDETADIKRA VSSILMSKTF 240
  241 DNGVVCASEQ AVIVVDSIYE QVKERFATHG GYLLNAAQTE AMQQVILKNG GLNADIVGQS 300
  301 AATIAQMAGI EVPHTTKVLI GEVTDISETE AFAHEKLSPL LGMYRAADFN DAVDKAETLV 360
  361 ALGGIGHTSG LYTDQDTQTE RVKSFGFRMK TARILINTPA SQGGIGDLYN FKLAPSLTLG 420
  421 CGSWGGNSIS ENVGPSHLIN KKTVAKRAEN MLWHKLPSSI YFRRGSLPIA LEELSDKKRA 480
  481 LIVTDPFLFN QGYCDETLKI LKAQGLETEV FYEVEADPTL ATVRQGAKVA NSFKPDVIIA 540
  541 LGGGSPMDAA KIIWVMYEHP DVDFADLALR FMDIRKRIYK FPKMGVKATM VAIPTTSGTG 600
  601 SEVTPFAVVT DEQTGKKYPI ADYQLTPNMA IVDPNLVMDM PKSLTAFGGI DAITHALEAY 660
  661 VSVMANEYSD GQALQALDLL CKYLPDAYQL GAASPIAREK VHNGATIAGI AFANAFLGIC 720
  721 HSMAHKLGAE FHLAHGLANA LLISNVIRFN ATDLPTKQAA FSQYDRPKAL CRYAAIADHL 780
  781 ALGGNSDAQK VEKLLEKIEQ LKKTLGIPAS IQEAGVNEAD FLAKLDMLAE DAFDDQCTGA 840
  841 NPRYPLISEL KQLLLDSYYG RPFTEQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..449]	PSI-BLAST	132.0	Aldehyde reductase (dehydrogenase), ALDH
2	View Details	[450..866]	PSI-BLAST	91.69897	Crystal Structure of Lactaldehyde reductase

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
oxidoreductase activity	4.47226217021998	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	4.34495776828926	bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity	3.37049090049734	bayes_pls_golite062009
succinate-semialdehyde dehydrogenase [NAD(P)+] activity	3.30681232755737	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	3.2867555127991	bayes_pls_golite062009
aldehyde dehydrogenase (NAD) activity	2.81851373615334	bayes_pls_golite062009
catalytic activity	2.80804701752928	bayes_pls_golite062009
succinate-semialdehyde dehydrogenase activity	2.25908515251731	bayes_pls_golite062009
benzaldehyde dehydrogenase activity	1.80313175632526	bayes_pls_golite062009
methylmalonate-semialdehyde dehydrogenase (acylating) activity	1.59279206536309	bayes_pls_golite062009
1-pyrroline-5-carboxylate dehydrogenase activity	1.15620590715864	bayes_pls_golite062009
binding	0.637403449596354	bayes_pls_golite062009

2

Term	Confidence	Notes
alcohol dehydrogenase (NAD) activity	5.26400058766942	bayes_pls_golite062009
oxidoreductase activity	3.07409531087588	bayes_pls_golite062009
alcohol dehydrogenase activity, metal ion-independent	3.05722501802075	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	2.83823088483915	bayes_pls_golite062009
catalytic activity	2.37357608468991	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2.10085302216488	bayes_pls_golite062009
binding	1.15096180564234	bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity	0.831155115586418	bayes_pls_golite062009
cation binding	0.319000821544479	bayes_pls_golite062009
metal ion binding	0.319000821544479	bayes_pls_golite062009
ion binding	0.313606245452103	bayes_pls_golite062009
protein binding	0.295023706645045	bayes_pls_golite062009
transition metal ion binding	0.259889634539407	bayes_pls_golite062009
hydroxyacid-oxoacid transhydrogenase activity	0.146499147589879	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.0904828025133766	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.81

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle