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Protein Overview: gi|24372429, gi|...

General Information:
Name(s) found: gi|24372429 [NCBI NR]
gi|24346403 [NCBI NR]
Description(s) found:
Found 4 descriptions.
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  • gi|24372429|ref|NP_716471.1| acetyl-CoA carboxylase multifunctional enzyme accADC, carboxyl transferase subunit alpha/carboxyl transferase subunit beta/biotin carboxylase [Shewanella oneidensis MR-1] [NCBI NR]
  • gi|24346403|gb|AAN53916.1|AE015528_9 acetyl-CoA carboxylase multifunctional enzyme accADC, carboxyl transferase subunit alpha/carboxyl transferase subunit beta/biotin carboxylase [Shewanella oneidensis MR-1] [NCBI NR]
    • Organism: Shewanella oneidensis MR-1
    Length: 1517 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: lipid metabolic process [ISSLink to PubMed article]
    Molecular Function: acetyl-CoA carboxylase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSNNQPKHM TQAQTPDPLF LQAEHLAKDF SLFPKHSKQS LSEEIKGLLN DDAIQANLKD  60
   61 LASLDVDGYV AKVIQPTQDK GRPGAKRIIA DLKGRLITET HLGSFYSAEV ELNFGSRTRR 120
  121 IGFIAQERTT ANGAWMPEHH YAACKAIRHF AELSMPIVYL IDTPGADAGE VANSQNQAHS 180
  181 ISKAIAESAN VDVPTVGIVI GAGYSGGAIP LAAANILLSL RDGIFNTIQP QGLQSIARKY 240
  241 NLSWQECAKS VGVSPEELYT SGCIDGIIDF SPGDRDERQH NLRRAIISSI EAVERAAVNF 300
  301 VRESKDLREH YDRSLARFLN PSKNLMALEL NAELAVATSP TNHHNLFGSA YRYLRYLTLR 360
  361 SRIHSISQEQ YGRLSRVSVP EGDLLARIQQ EQDRVFQAWL ASPDKLVYDE DLNKLWANFI 420
  421 AKRDEISTER NMLTRFILGE PKENYKKARK ALLFNISWSL YHRWKSNAAN NFKGLIQHLE 480
  481 NLPKSVTQAK WPELNQLTVL DVVVNDELRE DFIWQCHNIL IFNSLYDNVV GSLASIAKEA 540
  541 MMSKSLSRNS VNNLLHKSID HALSTQDTAN DKAKFYKWLK YFMGQSNRAD LLVRVEQWKS 600
  601 VGFPQLNDSL FVILTYFFER LLPEYFDSES DHSKYTGAIN PVRIGRRKDF WNRLTMGYQD 660
  661 LLIQKVLRDE KRTGKMTWEN VIKQFFTHFD EINGDKMSAN LLNFPGFRLS IEDALDKGIR 720
  721 PCGLITGIAD FKEKGQKVRV GLAVSNTAFQ AGAFDMASAE KFSALLIECA KRKLPVVCFI 780
  781 SSGGMQTKEG AAALFSMAVV NDRITRFIRD NELPVLMFGF GDCTGGAQAS FVTHPLVQTY 840
  841 YLSGTNMPFA GQMVVPAYLP STSTLSNYLS KVPGAMAGLV HNPFSENLDN QLASIDPLMP 900
  901 MPTAKINEVI INALSTLVVE APAEEEEIVQ NDPRKLMKPI NKVLVHARGC TAVKLIRKAH 960
  961 DNNINVVLVA SDPDMTAVPA DMLKESDKLV CLGGNTSDES YLNAYSVLKV AEYEQVDALH1020
 1021 PGIGFLSESP QFAALCVNNG VNFVGPSVHS MTTMGNKSNA IKTSQAQNVP VVPGSHGILT1080
 1081 NAEQAVNVAS EIGYPVLLKA VQGGGGKGIQ VVKRPEDMIG LFQKTATEAA AAFGNGDLYL1140
 1141 EKYVTSLRHI EVQLLRDKFG HAKVLGLRDC SVQRNNQKVV EESGSTMLPD ELKKQVLAYT1200
 1201 RALGDATDYM GAGTVEFIYN LDANEVYFME MNTRLQVEHP VTEATSGIDI VSAQFDIAAG1260
 1261 RSIEHLEPKE IGYAMEVRVT AEKAALDSHG VLQLIPNPGK ITECVFPDHP DVEIISIAAP1320
 1321 GKEVSPYYDS LIAQVIMRGE NREDVIAKLH AYLDSVVLKG IATNIPLLKL ILSDGTFKEG1380
 1381 VYDTNYLPRF MAELDIPALI AEMEAAAETV GVDTESLRVG ESNELKVLAQ GAGIFYTSPA1440
 1441 PGEPDFVKEG DIVTAEQTLA LTEAMKMFSQ VNLAGFNRQG AVLYPEDKKY RIERILNSNG1500
 1501 QQVSQGDLLF VVSPVED

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..305] PSI-BLAST 85.39794 Crystal structure of propionyl-CoA carboxylase, beta subunit (TM0716) from THERMOTOGA MARITIMA at 2.30 A resolution
    2 View Details [306..403] deduced N/A No confident structure predictions are available.
    3 View Details [404..624] MSA 1.019963 View MSA. No confident structure predictions are available.
    4 View Details [625..677] PSI-BLAST 53.69897 No description for 2f9yB was found.
    5 View Details [678..1373] PSI-BLAST 90.39794 Carbamoyl phosphate synthetase, large subunit connection domain; Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain; Carbamoyl phosphate synthetase (CPS), large subunit PreATP-grasp domains; Carbamoyl phosphate synthetase (CPS), large subunit ATP-binding domains
    6 View Details [1374..1517] PSI-BLAST 119.0 No description for 2qf7A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • acetyl-CoA carboxylase activity
    		•  10.6452464693016 bayes_pls_golite062009
  • CoA carboxylase activity
    		•  10.4560118435089 bayes_pls_golite062009
  • ligase activity, forming carbon-carbon bonds
    		•  10.291155621143 bayes_pls_golite062009
  • ligase activity
    		•  5.44906329604668 bayes_pls_golite062009
  • biotin carboxylase activity
    		•  4.73758144982083 bayes_pls_golite062009
  • enoyl-CoA hydratase activity
    		•  2.20341273353803 bayes_pls_golite062009
  • catalytic activity
    		•  1.46154163027498 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  0.71437881404683 bayes_pls_golite062009
  • dodecenoyl-CoA delta-isomerase activity
    		•  0.712418056146834 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing C=C bonds
    		•  0.0918189681606029 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • CoA carboxylase activity
    		•  9.83581323285097 bayes_pls_golite062009
  • ligase activity, forming carbon-carbon bonds
    		•  9.81059565938621 bayes_pls_golite062009
  • acetyl-CoA carboxylase activity
    		•  9.76633430002009 bayes_pls_golite062009
  • ligase activity
    		•  7.71401892529536 bayes_pls_golite062009
  • biotin carboxylase activity
    		•  6.9547407447638 bayes_pls_golite062009
  • carbamoyl-phosphate synthase activity
    		•  4.25267317906061 bayes_pls_golite062009
  • carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
    		•  4.17451795830682 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  3.45358843752722 bayes_pls_golite062009
  • catalytic activity
    		•  2.5009559386228 bayes_pls_golite062009
  • phosphoribosylaminoimidazole carboxylase activity
    		•  1.57708889650281 bayes_pls_golite062009
  • carbon-nitrogen ligase activity, with glutamine as amido-N-donor
    		•  1.11645327303429 bayes_pls_golite062009
  • phosphoribosylamine-glycine ligase activity
    		•  1.04915286326924 bayes_pls_golite062009
  • ligase activity, forming carbon-sulfur bonds
    		•  0.695070201354335 bayes_pls_golite062009
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle