Protein Overview: GCSP_SHEON

General Information:
Name(s) found:	GCSP_SHEON [Swiss-Prot]
Description(s) found: Found 6 descriptions. SHOW ALL	Glycine dehydrogenase (decarboxylating) OS=Shewanella oneidensis (strain MR-1) GN=gcvP PE=3 SV=1 [Swiss-Prot]
Organism:	Shewanella oneidensis MR-1
Length:	962 amino acids
Gene Ontology:
Cellular Component:	glycine cleavage complex [ISS]
Biological Process:	glycine catabolic process [ISS]
Molecular Function:	glycine dehydrogenase (decarboxylating) activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKQTLTQLE QHDLFLRRHI GPDSSQQQEM LNYVGAESLD DLTAQIVPES IRLSQELSIG  60
   61 DSCGEAEGIA YIRGLAKQNQ VFKSYIGMGY YGTQVPNVIL RNVLENPGWY TAYTPYQPEI 120
  121 AQGRLEAILN FQQVSMDLTG LDLASASLLD EATAAAEAMA LAKRVSKAKK ANIFFVADDV 180
  181 FPQTLDVVKT RAECFGFEVV VGPASEAVNH ELFGALFQYS NRFGQITDFT DLFAELRAKN 240
  241 VIVTVAADIM SLVLLKSPGS MGADVVFGSA QRFGVPMGFG GPHAAFFVAR DEHKRSMPGR 300
  301 IIGVSKDTRG NRALRMAMQT REQHIRREKA NSNICTAQIL LANMASFYAV FHGPQGLKTI 360
  361 ASRINRFADI LAAGLQAKGV SLVNNTWFDT ISIKGLDVAA VNARALAAEM NLRFDADGIV 420
  421 GVSLDETTIR TDIDALFEVI LGAGHGLDVA ALDAQIVAQG SQSIPASLVR EDAILSHPTF 480
  481 NRYQSETEMM RYIKRLESKD LALNYSMISL GSCTMKLNAA VEMIPVSWPE FANMHPFCPL 540
  541 DQAKGYTQLI EELSSWLVNV TGYDAVCIQP NSGAQGEYAG LLAIRKYHES RGEAHRNICL 600
  601 IPQSAHGTNP ASAQLAGMQV VVTACDKQGN VDLEDLKAKA AEVAENLSCI MITYPSTHGV 660
  661 YEETVREICN IVHQHGGQVY LDGANMNAQV GLTSPGFIGA DVSHLNLHKT FAIPHGGGGP 720
  721 GMGPIGVKAH LAPFVAGHVV VKPGRESDNN GAVSAAPYGS AGILPISWMY IKLLGSKGLK 780
  781 KSTQTALLNA NYVMKKLSEH YPVLFRGRND RVAHECIIDL RPIKEASGVT EMDIAKRLND 840
  841 YGFHAPTMSF PVAGTLMIEP TESESKVELD RFIDAMVSIR AEIAKVEAGE WPADNNPLHN 900
  901 APHTMADIMD SAFDSRPYSR EVAVFPSAAV RTNKFWPTVN RIDDVYGDRN LFCACVPLSD 960
  961 YE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..447]	PSI-BLAST	64.39794	Crystal structure of glycine decarboxylase (P-protein) of the glycine cleavage system, in apo form
2	View Details	[448..962]	PSI-BLAST	60.221849	Crystal structure of glycine decarboxylase (P-protein) of the glycine cleavage system, in apo form

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
glycine dehydrogenase (decarboxylating) activity	8.00572280567771	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	8.00572280567771	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors	3.14486270422678	bayes_pls_golite062009
catalytic activity	2.29878871754893	bayes_pls_golite062009
transferase activity	1.44093490824786	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
methyltransferase activity	0.681623261233707	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	0.619695949258279	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.60304280865376	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	0.271623203801431	bayes_pls_golite062009
O-phospho-L-serine:2-oxoglutarate aminotransferase activity	0.234399054481664	bayes_pls_golite062009
pyridoxal phosphate binding	0.16957228630576	bayes_pls_golite062009
vitamin B6 binding	0.16957228630576	bayes_pls_golite062009

2

Term	Confidence	Notes
glycine dehydrogenase (decarboxylating) activity	8.00572280567771	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	8.00572280567771	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors	3.14486270422678	bayes_pls_golite062009
catalytic activity	2.29878871754893	bayes_pls_golite062009
transferase activity	1.44093490824786	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
methyltransferase activity	0.681623261233707	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	0.619695949258279	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.60304280865376	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	0.271623203801431	bayes_pls_golite062009
O-phospho-L-serine:2-oxoglutarate aminotransferase activity	0.234399054481664	bayes_pls_golite062009
pyridoxal phosphate binding	0.16957228630576	bayes_pls_golite062009
vitamin B6 binding	0.16957228630576	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.80

Source: Reynolds et al. (2008)

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