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Protein Overview: gi|24371957, gi|...

General Information:
Name(s) found: gi|24371957 [NCBI NR]
gi|24345803 [NCBI NR]
Description(s) found:
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  • gi|24371957|ref|NP_715999.1| bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [Shewanella oneidensis MR-1] [NCBI NR]
  • gi|24345803|gb|AAN53444.1|AE015484_2 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [Shewanella oneidensis MR-1] [NCBI NR]
  • guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [Shewanella oneidensis MR-1]gi|24345803|gb|AAN53444.1| guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [Shewanella oneidensis MR-1] [nrdb_11152004_Chlamydomonas]
  • guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [Shewanella oneidensis MR-1] [nr-271106-contam.fasta]
    • Organism: Shewanella oneidensis MR-1
    Length: 701 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: cellular response to starvation [ISSLink to PubMed article]
    Molecular Function: guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYLFEGLKES ASGYLEPEQV ELLKQAYQVA RDAHEGQMRT SGEPYITHPV AVARILAEMR  60
   61 LDHETLMAAL LHDTIEDTYV TKEDLAERFG ESVAELVEGV SKLDKLKFRD KKEAQAENFR 120
  121 KMMMAMTQDI RVILIKLADR THNMRTLGAL RPDKRRRIAR ETLEIYAPIA NRLGIHNIKT 180
  181 ELEDLGFQAY YPMRYRVLKE VVKAARGNRK ELIQGIEAAV LTRLNDAGIK GKVKGREKNL 240
  241 YSIYNKMQSK ELQFQEVMDI YAFRVIVDSI DTCYRVLGAM HGLYKPRPGR FKDYIAIPKA 300
  301 NGYQSLHTSL FGPHGVPVEI QIRTEDMDQM ADKGVAAHWA YKGGAETGQG TTTQVRARKW 360
  361 MQSLLELQQS ASTSFEFVEN VKTELFPEEI YVFTPEGRIL ELPVNATAVD FAYEVHTDVG 420
  421 NTCVGARVNR QAYPLSQPLI SGQTVEIITA KGARPNAAWL NFVVTGKARA KIRQVLKSLK 480
  481 GDDAIALGRR LLNHALGKTK LDSIPAEQIE KVVRDTKHAS LNALLADIGL GNAMSIVIAQ 540
  541 RLIGDNLENQ ESRDSHQMPI RGAEGMLVTF ANCCRPIPGD AVIAHVSQGK GLVVHMENCA 600
  601 NIRGYQSEPD KYIPVQWDNV EGVEYQANLR VEIVNHQGAL AKITSIIAAE GSNIHNLSTE 660
  661 ERDGRVYLIN LRISVKDRIH LANVMRRIRV LPEVLRTSRN R

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..386] PSI-BLAST 129.0 Crystal structure of the bifunctional catalytic fragment of RelSeq, the RelA/SpoT homolog from Streptococcus equisimilis.
    2 View Details [387..571] PSI-BLAST 24.30103 Structure of Staphylococcus aureus threonyl-tRNA synthetase complexed with an analogue of threonyl adenylate
    3 View Details [572..701] PSI-BLAST 12.69897 Crystal structure of the regulatory subunit of acetohydroxyacid synthase isozyme III from E. coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • GTP diphosphokinase activity
    		•  1.5953523101767 bayes_pls_golite062009
  • cyclic-nucleotide phosphodiesterase activity
    		•  1.53556412385088 bayes_pls_golite062009
  • 3',5'-cyclic-nucleotide phosphodiesterase activity
    		•  1.52960140313397 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.17940277430091 bayes_pls_golite062009
  • guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity
    		•  1.1479499593037 bayes_pls_golite062009
  • diphosphoric monoester hydrolase activity
    		•  1.1479499593037 bayes_pls_golite062009
  • catalytic activity
    		•  1.122769147009 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.92178707322923 bayes_pls_golite062009
  • hydrolase activity
    		•  0.89382287998944 bayes_pls_golite062009
  • phosphoric diester hydrolase activity
    		•  0.874654356902841 bayes_pls_golite062009
  • transferase activity
    		•  0.63270331673446 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.262138492248739 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.196287846714023 bayes_pls_golite062009
  • 3',5'-cyclic-AMP phosphodiesterase activity
    		•  0.0897894719596 bayes_pls_golite062009
  • 3',5'-cyclic-GMP phosphodiesterase activity
    		•  0.0229959143092802 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • transferase activity, transferring aldehyde or ketonic groups
    		•  1.58611270031811 bayes_pls_golite062009
  • catalytic activity
    		•  1.01569611874813 bayes_pls_golite062009
  • binding
    		•  0.162590183060409 bayes_pls_golite062009
  • transferase activity
    		•  0.07375530569672 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle