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Protein Overview: ACND_SHEON

General Information:
Name(s) found: ACND_SHEON [Swiss-Prot]
Description(s) found:
Found 6 descriptions.
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  • 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) OS=Shewanella oneidensis (strain MR-1) GN=acnD PE=1 SV=1 [Swiss-Prot]
    • Organism: Shewanella oneidensis MR-1
    Length: 867 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: tricarboxylic acid cycle [ISSLink to PubMed article]
    Molecular Function: aconitate hydratase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTVMNTQYR KPLPGTALDY FDTREAIEAI APGAYAKLPY TSRVLAENLV RRCEPEMLTA  60
   61 SLKQIIESKQ ELDFPWFPAR VVCHDILGQT ALVDLAGLRD AIAAKGGDPA QVNPVVPTQL 120
  121 IVDHSLAVEY GGFDKDAFAK NRAIEDRRNE DRFHFINWTQ KAFKNIDVIP QGNGIMHQIN 180
  181 LERMSPVIHA RNGVAFPDTL VGTDSHTPHV DALGVIAIGV GGLEAESVML GRASYMRLPD 240
  241 IIGVELTGKP QPGITATDIV LALTEFLRAQ KVVSSYLEFF GEGAEALTLG DRATISNMTP 300
  301 EFGATAAMFY IDQQTLDYLT LTGREAEQVK LVETYAKTAG LWSDDLKQAV YPRTLHFDLS 360
  361 SVVRTIAGPS NPHARVPTSE LAARGISGEV ENEPGLMPDG AVIIAAITSC TNTSNPRNVI 420
  421 AAGLLARNAN AKGLTRKPWV KTSLAPGSKA VQLYLEEANL LPELESLGFG IVGFACTTCN 480
  481 GMSGALDPVI QQEVIDRDLY ATAVLSGNRN FDGRIHPYAK QAFLASPPLV VAYAIAGTIR 540
  541 FDIEKDVLGL DKDGKPVRLI NIWPSDAEID AVIAASVKPE QFRKVYEPMF DLSVDYGDKV 600
  601 SPLYDWRPQS TYIRRPPYWE GALAGERTLK GMRPLAVLGD NITTDHLSPS NAIMMDSAAG 660
  661 EYLHKMGLPE EDFNSYATHR GDHLTAQRAT FANPKLKNEM AIVDGKVKQG SLARIEPEGI 720
  721 VTRMWEAIET YMDRKQPLII IAGADYGQGS SRDWAAKGVR LAGVEAIVAE GFERIHRTNL 780
  781 VGMGVLPLEF KAGENRATYG IDGTEVFDVI GSIAPRADLT VIITRKNGER VEVPVTCRLD 840
  841 TAEEVSIYEA GGVLQRFAQD FLESNLK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..867] PSI-BLAST 1000.0 Structure of an orthorhombic crystal form of human cytosolic aconitase (IRP1)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3-isopropylmalate dehydratase activity
    		•  11.6597692115322 bayes_pls_golite062009
  • aconitate hydratase activity
    		•  5.86356477922338 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  5.49717480487827 bayes_pls_golite062009
  • structural molecule activity
    		•  5.20352686802457 bayes_pls_golite062009
  • catalytic activity
    		•  2.4040324437254 bayes_pls_golite062009
  • mRNA binding
    		•  2.2758554402042 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.25736437672211 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  2.08349115784849 bayes_pls_golite062009
  • hydro-lyase activity
    		•  2.04845291489052 bayes_pls_golite062009
  • lyase activity
    		•  2.0080619912194 bayes_pls_golite062009
  • RNA binding
    		•  2.00311670878109 bayes_pls_golite062009
  • metal cluster binding
    		•  1.70706327499066 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  1.70706327499066 bayes_pls_golite062009
  • binding
    		•  1.67914740974449 bayes_pls_golite062009
  • DNA binding
    		•  1.6436451615422 bayes_pls_golite062009
  • iron-responsive element binding
    		•  1.1980380564483 bayes_pls_golite062009
  • iron ion binding
    		•  1.12961684198784 bayes_pls_golite062009
  • 4 iron, 4 sulfur cluster binding
    		•  1.11810757572823 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.342428816025605 bayes_pls_golite062009
  • protein binding
    		•  0.232638130896339 bayes_pls_golite062009
  • cation binding
    		•  0.0272064751959212 bayes_pls_golite062009
  • metal ion binding
    		•  0.0272064751959212 bayes_pls_golite062009
  • ion binding
    		•  0.0228992031160024 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle