Protein Overview: SLN1_YEAST

General Information:
Name(s) found:	SLN1_YEAST [Swiss-Prot]
Description(s) found:	Osmosensing histidine protein kinase SLN1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SLN1 PE=1 SV=1 [Swiss-Prot]
Organism:	Saccharomyces cerevisiae S288c
Length:	1220 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFGLPSKLE LTPPFRIGIR TQLTALVSIV ALGSLIILAV TTGVYFTSNY KNLRSDRLYI  60
   61 AAQLKSSQID QTLNYLYYQA YYLASRDALQ SSLTSYVAGN KSADNWVDSL SVIQKFLSSS 120
  121 NLFYVAKVYD SSFNAVLNAT NNGTGDLIPE DVLDSLFPLS TDTPLPSSLE TIGILTDPVL 180
  181 NSTDYLMSMS LPIFANPSII LTDSRVYGYI TIIMSAEGLK SVFNDTTALE HSTIAIISAV 240
  241 YNSQGKASGY HFVFPPYGSR SDLPQKVFSI KNDTFISSAF RNGKGGSLKQ TNILSTRNTA 300
  301 LGYSPCSFNL VNWVAIVSQP ESVFLSPATK LAKIITGTVI AIGVFVILLT LPLAHWAVQP 360
  361 IVRLQKATEL ITEGRGLRPS TPRTISRASS FKRGFSSGFA VPSSLLQFNT AEAGSTTSVS 420
  421 GHGGSGHGSG AAFSANSSMK SAINLGNEKM SPPEEENKIP NNHTDAKISM DGSLNHDLLG 480
  481 PHSLRHNDTD RSSNRSHILT TSANLTEARL PDYRRLFSDE LSDLTETFNT MTDALDQHYA 540
  541 LLEERVRART KQLEAAKIEA EAANEAKTVF IANISHELRT PLNGILGMTA ISMEETDVNK 600
  601 IRNSLKLIFR SGELLLHILT ELLTFSKNVL QRTKLEKRDF CITDVALQIK SIFGKVAKDQ 660
  661 RVRLSISLFP NLIRTMVLWG DSNRIIQIVM NLVSNALKFT PVDGTVDVRM KLLGEYDKEL 720
  721 SEKKQYKEVY IKKGTEVTEN LETTDKYDLP TLSNHRKSVD LESSATSLGS NRDTSTIQEE 780
  781 ITKRNTVANE SIYKKVNDRE KASNDDVSSI VSTTTSSYDN AIFNSQFNKA PGSDDEEGGN 840
  841 LGRPIENPKT WVISIEVEDT GPGIDPSLQE SVFHPFVQGD QTLSRQYGGT GLGLSICRQL 900
  901 ANMMHGTMKL ESKVGVGSKF TFTLPLNQTK EISFADMEFP FEDEFNPESR KNRRVKFSVA 960
  961 KSIKSRQSTS SVATPATNRS SLTNDVLPEV RSKGKHETKD VGNPNMGREE KNDNGGLEQL1020
 1021 QEKNIKPSIC LTGAEVNEQN SLSSKHRSRH EGLGSVNLDR PFLQSTGTAT SSRNIPTVKD1080
 1081 DDKNETSVKI LVVEDNHVNQ EVIKRMLNLE GIENIELACD GQEAFDKVKE LTSKGENYNM1140
 1141 IFMDVQMPKV DGLLSTKMIR RDLGYTSPIV ALTAFADDSN IKECLESGMN GFLSKPIKRP1200
 1201 KLKTILTEFC AAYQGKKNNK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..161]	MSA	1.004953	View MSA. No confident structure predictions are available.
2	View Details	[162..264]	deduced	N/A	No confident structure predictions are available.
3	View Details	[265..553]	MSA	3.553989	View MSA. No confident structure predictions are available.
4	View Details	[554..670]	ORFEUS	14.04	EnvZ histidine kinase
5	View Details	[671..785]	MSA	4.272994	View MSA. Confident ab initio structure predictions are available.
6	View Details	[786..939]	PSI-BLAST	81.68867	Histidine kinase domain of the osmosensor EnvZ
7	View Details	[940..1085]	PSI-BLAST	13.69897	Transcriptional regulatory protein DctD, receiver domain
8	View Details	[1086..1220]	PSI-BLAST	123.156545	CheY protein

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

No functions predicted.

3

No functions predicted.

4

No functions predicted.

5

No functions predicted.

6

Term	Confidence	Notes
two-component response regulator activity	6.41182973389827	bayes_pls_golite062009
molecular transducer activity	6.27803885496668	bayes_pls_golite062009
signal transducer activity	6.27803885496668	bayes_pls_golite062009
protein kinase activity	2.91563392647119	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	2.4588656102875	bayes_pls_golite062009
kinase activity	2.26401916756851	bayes_pls_golite062009
transcription regulator activity	2.23448171655589	bayes_pls_golite062009
binding	1.92400975854452	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.64567362100773	bayes_pls_golite062009
protein histidine kinase activity	1.60632989169905	bayes_pls_golite062009
two-component sensor activity	1.58303578136745	bayes_pls_golite062009
DNA binding	1.58172125522651	bayes_pls_golite062009
nucleic acid binding	1.56306133971215	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	1.45748315828993	bayes_pls_golite062009
receptor activity	1.17008073803454	bayes_pls_golite062009
transmembrane receptor activity	1.10773580590429	bayes_pls_golite062009
transcription factor activity	0.970571914515176	bayes_pls_golite062009
transferase activity	0.626277634156636	bayes_pls_golite062009

7

Term	Confidence	Notes
two-component response regulator activity	6.41182973389827	bayes_pls_golite062009
molecular transducer activity	6.27803885496668	bayes_pls_golite062009
signal transducer activity	6.27803885496668	bayes_pls_golite062009
protein kinase activity	2.91563392647119	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	2.4588656102875	bayes_pls_golite062009
kinase activity	2.26401916756851	bayes_pls_golite062009
transcription regulator activity	2.23448171655589	bayes_pls_golite062009
binding	1.92400975854452	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.64567362100773	bayes_pls_golite062009
protein histidine kinase activity	1.60632989169905	bayes_pls_golite062009
two-component sensor activity	1.58303578136745	bayes_pls_golite062009
DNA binding	1.58172125522651	bayes_pls_golite062009
nucleic acid binding	1.56306133971215	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	1.45748315828993	bayes_pls_golite062009
receptor activity	1.17008073803454	bayes_pls_golite062009
transmembrane receptor activity	1.10773580590429	bayes_pls_golite062009
transcription factor activity	0.970571914515176	bayes_pls_golite062009
transferase activity	0.626277634156636	bayes_pls_golite062009

8

No functions predicted.

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

Philius confidence legend

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