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Protein Overview: NFS1_YEAST

General Information:
Name(s) found: NFS1_YEAST [Swiss-Prot]
Description(s) found:
  • Cysteine desulfurase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NFS1 PE=1 SV=2 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 497 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKSTATRSI TRLSQVYNVP AATYRACLVS RRFYSPPAAG VKLDDNFSLE THTDIQAAAK  60
   61 AQASARASAS GTTPDAVVAS GSTAMSHAYQ ENTGFGTRPI YLDMQATTPT DPRVLDTMLK 120
  121 FYTGLYGNPH SNTHSYGWET NTAVENARAH VAKMINADPK EIIFTSGATE SNNMVLKGVP 180
  181 RFYKKTKKHI ITTRTEHKCV LEAARAMMKE GFEVTFLNVD DQGLIDLKEL EDAIRPDTCL 240
  241 VSVMAVNNEI GVIQPIKEIG AICRKNKIYF HTDAAQAYGK IHIDVNEMNI DLLSISSHKI 300
  301 YGPKGIGAIY VRRRPRVRLE PLLSGGGQER GLRSGTLAPP LVAGFGEAAR LMKKEFDNDQ 360
  361 AHIKRLSDKL VKGLLSAEHT TLNGSPDHRY PGCVNVSFAY VEGESLLMAL RDIALSSGSA 420
  421 CTSASLEPSY VLHALGKDDA LAHSSIRFGI GRFSTEEEVD YVVKAVSDRV KFLRELSPLW 480
  481 EMVQEGIDLN SIKWSGH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..70] deduced N/A No confident structure predictions are available.
    2 View Details [71..104]
    [358..497]    		 PSI-BLAST 860.9897 NifS-like protein/selenocysteine lyase
    3 View Details [105..357] PSI-BLAST 860.9897 NifS-like protein/selenocysteine lyase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  3.40354781002256 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  3.40354781002256 bayes_pls_golite062009
  • transferase activity
    		•  2.59075614411581 bayes_pls_golite062009
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  2.30133284041702 bayes_pls_golite062009
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.67701710033155 bayes_pls_golite062009
  • DNA binding
    		•  1.4774443071095 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.39741122443159 bayes_pls_golite062009
  • cysteine desulfurase activity
    		•  1.30923778688541 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • transcription factor activity
    		•  1.15775909410582 bayes_pls_golite062009
  • binding
    		•  1.09053123792737 bayes_pls_golite062009
  • L-alanine:2-oxoglutarate aminotransferase activity
    		•  1.06988190956423 bayes_pls_golite062009
  • alanine-oxo-acid transaminase activity
    		•  1.06988190956423 bayes_pls_golite062009
  • ligase activity
    		•  0.827063849687833 bayes_pls_golite062009
  • structural molecule activity
    		•  0.754675308623467 bayes_pls_golite062009
  • carbon-sulfur lyase activity
    		•  0.698312655247044 bayes_pls_golite062009
  • 5-aminolevulinate synthase activity
    		•  0.54326874956263 bayes_pls_golite062009
  • cystathionine gamma-lyase activity
    		•  0.505859361763689 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.50269055590758 bayes_pls_golite062009
  • cystathionine beta-lyase activity
    		•  0.27933426619091 bayes_pls_golite062009
  • glycine hydroxymethyltransferase activity
    		•  0.271623203801431 bayes_pls_golite062009
  • O-phospho-L-serine:2-oxoglutarate aminotransferase activity
    		•  0.234399054481664 bayes_pls_golite062009
  • RNA binding
    		•  0.222777224430863 bayes_pls_golite062009
  • vitamin B6 binding
    		•  0.16957228630576 bayes_pls_golite062009
  • pyridoxal phosphate binding
    		•  0.16957228630576 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.103986924428507 bayes_pls_golite062009
  • sulfurtransferase activity
    		•  0.0450490929307473 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.0254276656964899 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle