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Protein Overview: IQG1_YEAST

General Information:
Name(s) found: IQG1_YEAST [Swiss-Prot]
Description(s) found:
  • Ras GTPase-activating-like protein IQG1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IQG1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1495 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAYSGSPSK PGNNNSYLNR YVENLGTNVT PPLRPQSSSK INSSLNIASP SHLKTKTSAS  60
   61 NSSATILSKK VESSVSKLKP SLPNKLVGKY TVDLSNYSKI ELRYYEFLCR VSEVKIWIEA 120
  121 VIEEALPSEI ELCVGDSLRN GVFLAKLTQR INPDLTTVIF PAGDKLQFKH TQNINAFFGL 180
  181 VEHVGVPDSF RFELQDLYNK KNIPQVFETL HILISMINKK WPGKTPALTN VSGQISFTKE 240
  241 EIAACKKAWP RIRDFKSLGT NINTAPASPE EPKEKRSGLI KDFNKFERPN IPVEEILITP 300
  301 RKNITDANCS DFSNTPSPYN EAPKMSNLDV VVEKRKFTPI EPSLLGPTPS LEYSPIKNKS 360
  361 LSYYSPTISK YLTYDTEFYT RRSRAREEDL NYYQTFKYSP SHYSPMRRER MTEEQFLEKV 420
  421 VQLQNICRGV NTRFNLYIQK RLLNLFEQDI LRFQACLRGN KFRVLSSMYL PIRRAKIDVP 480
  481 HVEAIQSRIK GSRIRYKYDK LKFTLSRFSC TVELLQAYCR SKLLKTTVNT KLNDIEISHY 540
  541 PLTKLQSYMR ASYVRKKVMS LNTKLNDERE SIMKFSAIIR GNVVRCSEDA ILSAVHDVHK 600
  601 ENISKLQSLI RGIFTRSCLA SIIYSLGKEN CNIIQLSACI RGNAVRHKVQ SLFAPENNLS 660
  661 ETVHDLQGLV RGILVRYTLD LVDDIVEYNN LALFQAFSRG ALVRESLDQK SSFYKRNVRS 720
  721 VIMIQSWIRK SLQRSAYLEL LDCPNPSLWA VKKFVHLLNG TATIEEVQNQ LESCQASLDS 780
  781 ENMKKERLLK SIRQQLNING VLDKFGLLKD KDHELGISDS TIPKSKYQKY EKLFYMLQVD 840
  841 PSYWKLLYLK EPEFVAKNVY MTFGTVNQRM NDRERSYFTR FVCEMLQNAI NEAPSIESFL 900
  901 DNRSQFWQTI LQDFLRRESP EFFSIIVPVL DYLSDPVVDF ESDPYKIYQE IHGFSSPQHC 960
  961 SPVDDASTKN KFIDNLRCLW HAIEMVAEIY TRKVHTIPVE IRYLCTKIFC YAADKNIEEI1020
 1021 DSLRAISSIL VNVFVSEYLV NREYYGYKDS NVQKNNQKID ILMKSLATVF EIKNFDGFLD1080
 1081 PLNQYANEIK PHIKDVLYNV LVDPEYEQEG DRLIYLDMVS PSPKLELLTE KVLEISGKFE1140
 1141 EYLNEFPEAD ILHDILEKNL DNSSFPRSGR VTLELDASAY RFLVSDDKMR KIYDQVKRAF1200
 1201 VYMMQIEDVD TNLYDLSIST ILPQDEPNFA NFLEQNPKIR DDPMIQKLKP LKYFTLKNVT1260
 1261 LKKIHELEST GTFCSSDNKL QNFLNDIANT IKNPNYAIDY VTQEIYITKE TLTKISEMNH1320
 1321 SLDIELSRLK KHVDHTIKDF QKAKDFSPVH KSKFGNFKNA VKKVQGRERS ELQGMKFKWN1380
 1381 TKQLYERGVL KTIRGEKLAE LTVKVFGSSG PKFPDIIFKI STSDGSRFGI QMIDKRKGPD1440
 1441 KRYSDDVDSF SFKDLIKTQV EPKIETWKLF HSNVVVNNSQ LLHLIVSFFY KRNAL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..86] deduced N/A No confident structure predictions are available.
    2 View Details [87..675] PSI-BLAST 149.0 Heavy meromyosin subfragment
    3 View Details [676..973] PSI-BLAST 149.0 Heavy meromyosin subfragment
    4 View Details [974..1168] PSI-BLAST 57.0 GAP related domain of neurofibromin
    5 View Details [1169..1249] deduced N/A No confident structure predictions are available.
    6 View Details [1250..1495] MSA 2.024962 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6
    Term Confidence Notes
  • actin binding
    		•  4.78749876353566 bayes_pls_golite062009
  • GTPase regulator activity
    		•  3.48313315541019 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  3.46216378778416 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  3.44145669357816 bayes_pls_golite062009
  • enzyme regulator activity
    		•  2.73117303901364 bayes_pls_golite062009
  • calmodulin binding
    		•  2.44376064579262 bayes_pls_golite062009
  • binding
    		•  2.21550924222852 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.52776228366828 bayes_pls_golite062009
  • protein binding
    		•  1.37785152807615 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  1.32591250158464 bayes_pls_golite062009
  • GTPase inhibitor activity
    		•  1.1177126331255 bayes_pls_golite062009
  • Rho GTPase binding
    		•  1.00104187823298 bayes_pls_golite062009
  • GTPase activator activity
    		•  0.945543525650563 bayes_pls_golite062009
  • small GTPase binding
    		•  0.78616895231719 bayes_pls_golite062009
  • GTPase binding
    		•  0.76727022636058 bayes_pls_golite062009
  • enzyme activator activity
    		•  0.514378360493585 bayes_pls_golite062009
  • enzyme binding
    		•  0.44096806806257 bayes_pls_golite062009
  • Ras GTPase binding
    		•  0.245740027562592 bayes_pls_golite062009
  • enzyme inhibitor activity
    		•  0.0914865633301911 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle