YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: IF2A_YEAST

General Information:
Name(s) found: IF2A_YEAST [Swiss-Prot]
Description(s) found:
  • Eukaryotic translation initiation factor 2 subunit alpha OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SUI2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 304 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTSHCRFYE NKYPEIDDIV MVNVQQIAEM GAYVKLLEYD NIEGMILLSE LSRRRIRSIQ  60
   61 KLIRVGKNDV AVVLRVDKEK GYIDLSKRRV SSEDIIKCEE KYQKSKTVHS ILRYCAEKFQ 120
  121 IPLEELYKTI AWPLSRKFGH AYEAFKLSII DETVWEGIEP PSKDVLDELK NYISKRLTPQ 180
  181 AVKIRADVEV SCFSYEGIDA IKDALKSAED MSTEQMQVKV KLVAAPLYVL TTQALDKQKG 240
  241 IEQLESAIEK ITEVITKYGG VCNITMPPKA VTATEDAELQ ALLESKELDN RSDSEDDEDE 300
  301 SDDE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..104] PSI-BLAST 438.218487 Eukaryotic initiation factor 2alpha, eIF2alpha, N-terminal domain
    2 View Details [105..222] PSI-BLAST 438.218487 Eukaryotic initiation factor 2alpha, eIF2alpha, N-terminal domain
    3 View Details [223..304] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • translation initiation factor activity
    		•  10.6089165352091 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  6.60650180781768 bayes_pls_golite062009
  • translation regulator activity
    		•  6.15562485158748 bayes_pls_golite062009
  • structural molecule activity
    		•  6.0174879876147 bayes_pls_golite062009
  • DNA binding
    		•  3.38561002225202 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.60981339834849 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  2.50756546575713 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  2.36609416429058 bayes_pls_golite062009
  • binding
    		•  2.263388192549 bayes_pls_golite062009
  • RNA binding
    		•  1.76502371106766 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.69669059514663 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.60662288414996 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.33094846641297 bayes_pls_golite062009
  • transferase activity
    		•  0.945564658432858 bayes_pls_golite062009
  • mRNA binding
    		•  0.883475899526061 bayes_pls_golite062009
  • transcription factor activity
    		•  0.859071050218437 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.77755643935497 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  0.474251377131502 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  0.47336621289748 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  0.47336621289748 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.448368263932591 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.40142383001471 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.33985916978927 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  0.16147560902991 bayes_pls_golite062009
  • protein binding
    		•  0.152645195799531 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle