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Protein Overview: EIF3C_YEAST

General Information:
Name(s) found: EIF3C_YEAST [Swiss-Prot]
Description(s) found:
  • Eukaryotic translation initiation factor 3 subunit C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NIP1 PE=1 SV=2 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 812 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRFFSSNYE YDVASSSSEE DLLSSSEEDL LSSSSSESEL DQESDDSFFN ESESESEADV  60
   61 DSDDSDAKPY GPDWFKKSEF RKQGGGSNKF LKSSNYDSSD EESDEEDGKK VVKSAKEKLL 120
  121 DEMQDVYNKI SQAENSDDWL TISNEFDLIS RLLVRAQQQN WGTPNIFIKV VAQVEDAVNN 180
  181 TQQADLKNKA VARAYNTTKQ RVKKVSRENE DSMAKFRNDP ESFDKEPTAD LDISANGFTI 240
  241 SSSQGNDQAV QEDFFTRLQT IIDSRGKKTV NQQSLISTLE ELLTVAEKPY EFIMAYLTLI 300
  301 PSRFDASANL SYQPIDQWKS SFNDISKLLS ILDQTIDTYQ VNEFADPIDF IEDEPKEDSD 360
  361 GVKRILGSIF SFVERLDDEF MKSLLNIDPH SSDYLIRLRD EQSIYNLILR TQLYFEATLK 420
  421 DEHDLERALT RPFVKRLDHI YYKSENLIKI METAAWNIIP AQFKSKFTSK DQLDSADYVD 480
  481 NLIDGLSTIL SKQNNIAVQK RAILYNIYYT ALNKDFQTAK DMLLTSQVQT NINQFDSSLQ 540
  541 ILFNRVVVQL GLSAFKLCLI EECHQILNDL LSSSHLREIL GQQSLHRISL NSSNNASADE 600
  601 RARQCLPYHQ HINLDLIDVV FLTCSLLIEI PRMTAFYSGI KVKRIPYSPK SIRRSLEHYD 660
  661 KLSFQGPPET LRDYVLFAAK SMQKGNWRDS VKYLREIKSW ALLPNMETVL NSLTERVQVE 720
  721 SLKTYFFSFK RFYSSFSVAK LAELFDLPEN KVVEVLQSVI AELEIPAKLN DEKTIFVVEK 780
  781 GDEITKLEEA MVKLNKEYKI AKERLNPPSN RR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..646] MSA 1.014001 View MSA. No confident structure predictions are available.
    2 View Details [647..706] deduced N/A No confident structure predictions are available.
    3 View Details [707..812] Pfam 15.420216 PCI domain No confident structure predictions are available.
    4 View Details [358..442] MSA 1.040983 View MSA. No confident structure predictions are available.
    5 View Details [443..535] deduced N/A No confident structure predictions are available.
    6 View Details [536..662] MSA 1.048959 View MSA. No confident structure predictions are available.
    7 View Details [663..812] FFAS03 1.9 Solution structure of the PCI domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7
    Term Confidence Notes
  • structural constituent of ribosome
    		•  2.974370828939 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.85334044543318 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.8293727459515 bayes_pls_golite062009
  • structural molecule activity
    		•  2.72616711594099 bayes_pls_golite062009
  • DNA binding
    		•  2.66906990480864 bayes_pls_golite062009
  • binding
    		•  2.14387047687719 bayes_pls_golite062009
  • transcription factor activity
    		•  1.97506348695089 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.665091289283954 bayes_pls_golite062009
  • transcription activator activity
    		•  0.542530812773621 bayes_pls_golite062009
  • protein binding
    		•  0.474083852700444 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.423955395883599 bayes_pls_golite062009
  • RNA binding
    		•  0.352569950847387 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle