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Protein Overview: DPB4_YEAST

General Information:
Name(s) found: DPB4_YEAST [Swiss-Prot]
Description(s) found:
  • DNA polymerase epsilon subunit D OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DPB4 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 196 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPKGWRKDA QGNYPTTSYI KEQENITIQD LLFPKSTIVN LAREVPQQSG KKLLINKDAS  60
   61 LALQRGATVF VNHLLLFARE IAKSQDKKSC SVDDVLSALD HIGHSALKGP VRDKLDEYQA 120
  121 AVEQRKKEKL DSGEVDADGD IDMGEDKENV PVEKVKEHDE IEEQGDALQD VEESSEKKQK 180
  181 TESQDVETRV QNLEQT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..34]
    [61..127]    		 PSI-BLAST 28.0 Negative cofactor 2, NC2, beta chain
    2 View Details [35..60]
    [128..196]    		 PSI-BLAST 28.0 Negative cofactor 2, NC2, beta chain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA-directed DNA polymerase activity
    		•  7.30463919195401 bayes_pls_golite062009
  • DNA polymerase activity
    		•  7.25909396656216 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  4.91761894051618 bayes_pls_golite062009
  • DNA binding
    		•  4.49118409263799 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.35201412176948 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.08606081850613 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  4.04353148658823 bayes_pls_golite062009
  • binding
    		•  3.27510691458843 bayes_pls_golite062009
  • transcription factor activity
    		•  2.51581622888695 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.38228606466152 bayes_pls_golite062009
  • transcription repressor activity
    		•  2.3574713307436 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.71244156762178 bayes_pls_golite062009
  • transferase activity
    		•  1.4922191078713 bayes_pls_golite062009
  • transcription corepressor activity
    		•  1.30859203490073 bayes_pls_golite062009
  • transcription activator activity
    		•  1.25487495162413 bayes_pls_golite062009
  • transcription factor binding
    		•  1.15204005455906 bayes_pls_golite062009
  • transcription coactivator activity
    		•  1.1297723528047 bayes_pls_golite062009
  • protein binding
    		•  1.07873333188144 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.01502031330902 bayes_pls_golite062009
  • centromeric DNA binding
    		•  0.6937627559147 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.0852726470007639 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle