Protein Overview: AVO1_YEAST

General Information:
Name(s) found:	AVO1_YEAST [Swiss-Prot]
Description(s) found:	Target of rapamycin complex 2 subunit AVO1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AVO1 PE=1 SV=1 [Swiss-Prot]
Organism:	Saccharomyces cerevisiae S288c
Length:	1176 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTVTVLNEL RAQFLRVCPE KDQMKRIIKP YIPVDEFNTE QCLDSSIREL YMNSDGVSLL  60
   61 PELESPPVSK DFMENYASLG KMRIMRENEG QKGKANQNLI GAEKTERDEE ETRNLQDKSA 120
  121 KNTLIVEENG TLRYNPLNSS ASNSLLNDDD HTSGKHHKTS SKEDSYLNSS MEMQKKSSKR 180
  181 SSLPFVRIFK SRRDHSNTSG NKNVMNTTNT RAKSSTLHPP GARHNKKGSK FDMNFDFDEN 240
  241 LEEEDDDDDD DEEGDDIHSQ FFQLDDDFDA KGSGASPAHK GINGMSNNKN NTYTNNRNSI 300
  301 SILDDRESSN GNIGSASRLK SHFPTSQKGK IFLTDNKNDG QKSDSLNANK GIHGDGSSAS 360
  361 GNGSVSRDGL TETESNNISD MESYINEKDL DDLNFDTVTS NINKTVSDLG GHESTNDGTA 420
  421 VMNRDSKDSR SNSNEFNAQN RDRITPGSSY GKSLLGSEYS EERYSNNDSS TMESGEMSLD 480
  481 SDMQTNTIPS HSIPMSMQKY GIYHGDDDST LNNVFDKAVL TMNSSRHPKE RRDTVISGKE 540
  541 PTSLTSSNRK FSVSSNLTST RSPLLRGHGR TSSTASSEHM KAPKVSDSVL HRARKSTLTL 600
  601 KQDHSQPSVP SSVHKSSKEG NILIEKTTDY LVSKPKASQL SNMFNKKKKR TNTNSVDVLE 660
  661 YFSFVCGDKV PNYESMGLEI YIQASKKYKR NSFTTKVRKS STIFEVIGFA LFLYSTEKKP 720
  721 DNFEEDGLTV EDISNPNNFS LKIVDEDGEP FEDNFGKLDR KSTIQSISDS EVVLCKVDDA 780
  781 EKSQNEIETP LPFETGGGLM DASTLDANSS HDTTDGTINQ LSFYKPIIGN EDDIDKTNGS 840
  841 KIIDVTVYLY PNVNPKFNYT TISVLVTSHI NDILVKYCKM KNMDPNEYAL KVLGKNYILD 900
  901 LNDTVLRLDG INKVELISKK DARELHLEKM KPDLKKPVLP TIQSNDLTPL TLEPLNSYLK 960
  961 ADAGGAVAAI PENTKVTSKA KKISTKYKLG LAKQHSSSSV ASGSVSTAGG LANGNGFFKN1020
 1021 KNSSKSSLHG TLQFHNINRS QSTMEHTPDT PNGVGDNFQD LFTGAYHKYK VWRRQQMSFI1080
 1081 NKHERTLAID GDYIYIVPPE GRIHWHDNVK TKSLHISQVV LVKKSKRVPE HFKIFVRREG1140
 1141 QDDIKRYYFE AVSGQECTEI VTRLQNLLSA YRMNHK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..615]	deduced	N/A	No confident structure predictions are available.
2	View Details	[616..791]	MSA	3.009964	View MSA. No confident structure predictions are available.
3	View Details	[792..1015]	deduced	N/A	No confident structure predictions are available.
4	View Details	[1016..1176]	MSA	1.004953	View MSA. No confident structure predictions are available.
5	View Details	[931..1051]	deduced	N/A	No confident structure predictions are available.
6	View Details	[1052..1176]	FFAS03	0.986	Solution Structure of the Pleckstrin Homology Domain of Human Protein Kinase B beta (Pkb/Akt)

Functions predicted (by domain):

#

Gene Ontology predictions

1

No functions predicted.

2

No functions predicted.

3

No functions predicted.

4

Term	Confidence	Notes
binding	2.0688320293797	bayes_pls_golite062009
protein binding	1.72968950672856	bayes_pls_golite062009
GTPase regulator activity	1.48723526514699	bayes_pls_golite062009
nucleoside-triphosphatase regulator activity	1.47132864518485	bayes_pls_golite062009
enzyme regulator activity	1.10772679848859	bayes_pls_golite062009
signal transducer activity	1.07208466109379	bayes_pls_golite062009
molecular transducer activity	1.07208466109379	bayes_pls_golite062009
small GTPase regulator activity	0.923576826164186	bayes_pls_golite062009
guanyl-nucleotide exchange factor activity	0.64016484101492	bayes_pls_golite062009
cytoskeletal protein binding	0.635109917427773	bayes_pls_golite062009
Ras guanyl-nucleotide exchange factor activity	0.0559591386917759	bayes_pls_golite062009

5

No functions predicted.

6

Term	Confidence	Notes
binding	2.52256824388179	bayes_pls_golite062009
protein binding	1.95763087285706	bayes_pls_golite062009
signal transducer activity	1.51882027675546	bayes_pls_golite062009
molecular transducer activity	1.51882027675546	bayes_pls_golite062009
GTPase regulator activity	1.50594272418871	bayes_pls_golite062009
nucleoside-triphosphatase regulator activity	1.48917924547615	bayes_pls_golite062009
actin binding	1.27269944962803	bayes_pls_golite062009
enzyme regulator activity	1.13267118951633	bayes_pls_golite062009
small GTPase regulator activity	1.10613306581585	bayes_pls_golite062009
cytoskeletal protein binding	0.972529924049714	bayes_pls_golite062009
protein domain specific binding	0.650240628628722	bayes_pls_golite062009
guanyl-nucleotide exchange factor activity	0.578612934164552	bayes_pls_golite062009
small GTPase binding	0.435164744647801	bayes_pls_golite062009
GTPase binding	0.423323808323435	bayes_pls_golite062009
receptor binding	0.391425518916624	bayes_pls_golite062009
receptor activity	0.361604826111032	bayes_pls_golite062009
transmembrane receptor activity	0.215248461701419	bayes_pls_golite062009
actin filament binding	2.21224577798385E-4	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle