| Protein: | AVO1_YEAST |
| Organism: | Saccharomyces cerevisiae S288c |
| Length: | 1176 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AVO1_YEAST.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1176] | [1..1176] |
|
|
0.0 | [456..920] | [87..515] |
|
|
0.0 | [456..920] | [72..500] |
|
|
6.0E-51 | [641..805] | [190..343] |
|
|
4.0E-47 | [1063..1172] | [48..154] |
|
|
3.0E-46 | [632..781] | [112..271] |
|
Region A: Residues: [1-615] |
1 11 21 31 41 51
| | | | | |
1 MDTVTVLNEL RAQFLRVCPE KDQMKRIIKP YIPVDEFNTE QCLDSSIREL YMNSDGVSLL 60
61 PELESPPVSK DFMENYASLG KMRIMRENEG QKGKANQNLI GAEKTERDEE ETRNLQDKSA 120
121 KNTLIVEENG TLRYNPLNSS ASNSLLNDDD HTSGKHHKTS SKEDSYLNSS MEMQKKSSKR 180
181 SSLPFVRIFK SRRDHSNTSG NKNVMNTTNT RAKSSTLHPP GARHNKKGSK FDMNFDFDEN 240
241 LEEEDDDDDD DEEGDDIHSQ FFQLDDDFDA KGSGASPAHK GINGMSNNKN NTYTNNRNSI 300
301 SILDDRESSN GNIGSASRLK SHFPTSQKGK IFLTDNKNDG QKSDSLNANK GIHGDGSSAS 360
361 GNGSVSRDGL TETESNNISD MESYINEKDL DDLNFDTVTS NINKTVSDLG GHESTNDGTA 420
421 VMNRDSKDSR SNSNEFNAQN RDRITPGSSY GKSLLGSEYS EERYSNNDSS TMESGEMSLD 480
481 SDMQTNTIPS HSIPMSMQKY GIYHGDDDST LNNVFDKAVL TMNSSRHPKE RRDTVISGKE 540
541 PTSLTSSNRK FSVSSNLTST RSPLLRGHGR TSSTASSEHM KAPKVSDSVL HRARKSTLTL 600
601 KQDHSQPSVP SSVHK
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [616-791] |
1 11 21 31 41 51
| | | | | |
1 SSKEGNILIE KTTDYLVSKP KASQLSNMFN KKKKRTNTNS VDVLEYFSFV CGDKVPNYES 60
61 MGLEIYIQAS KKYKRNSFTT KVRKSSTIFE VIGFALFLYS TEKKPDNFEE DGLTVEDISN 120
121 PNNFSLKIVD EDGEPFEDNF GKLDRKSTIQ SISDSEVVLC KVDDAEKSQN EIETPL
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [792-1015] |
1 11 21 31 41 51
| | | | | |
1 PFETGGGLMD ASTLDANSSH DTTDGTINQL SFYKPIIGNE DDIDKTNGSK IIDVTVYLYP 60
61 NVNPKFNYTT ISVLVTSHIN DILVKYCKMK NMDPNEYALK VLGKNYILDL NDTVLRLDGI 120
121 NKVELISKKD ARELHLEKMK PDLKKPVLPT IQSNDLTPLT LEPLNSYLKA DAGGAVAAIP 180
181 ENTKVTSKAK KISTKYKLGL AKQHSSSSVA SGSVSTAGGL ANGN
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1016-1176] |
1 11 21 31 41 51
| | | | | |
1 GFFKNKNSSK SSLHGTLQFH NINRSQSTME HTPDTPNGVG DNFQDLFTGA YHKYKVWRRQ 60
61 QMSFINKHER TLAIDGDYIY IVPPEGRIHW HDNVKTKSLH ISQVVLVKKS KRVPEHFKIF 120
121 VRREGQDDIK RYYFEAVSGQ ECTEIVTRLQ NLLSAYRMNH K
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| binding | 2.0688320293797 | bayes_pls_golite062009 |
| protein binding | 1.72968950672856 | bayes_pls_golite062009 |
| GTPase regulator activity | 1.48723526514699 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.47132864518485 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.10772679848859 | bayes_pls_golite062009 |
| signal transducer activity | 1.07208466109379 | bayes_pls_golite062009 |
| molecular transducer activity | 1.07208466109379 | bayes_pls_golite062009 |
| small GTPase regulator activity | 0.923576826164186 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 0.64016484101492 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.635109917427773 | bayes_pls_golite062009 |
| Ras guanyl-nucleotide exchange factor activity | 0.0559591386917759 | bayes_pls_golite062009 |
|
Region A: Residues: [931-1051] |
1 11 21 31 41 51
| | | | | |
1 KPDLKKPVLP TIQSNDLTPL TLEPLNSYLK ADAGGAVAAI PENTKVTSKA KKISTKYKLG 60
61 LAKQHSSSSV ASGSVSTAGG LANGNGFFKN KNSSKSSLHG TLQFHNINRS QSTMEHTPDT 120
121 P
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [1052-1176] |
1 11 21 31 41 51
| | | | | |
1 NGVGDNFQDL FTGAYHKYKV WRRQQMSFIN KHERTLAIDG DYIYIVPPEG RIHWHDNVKT 60
61 KSLHISQVVL VKKSKRVPEH FKIFVRREGQ DDIKRYYFEA VSGQECTEIV TRLQNLLSAY 120
121 RMNHK
|
| Detection Method: | |
| Confidence: | 0.986 |
| Match: | 1p6sA |
| Description: | Solution Structure of the Pleckstrin Homology Domain of Human Protein Kinase B beta (Pkb/Akt) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.52256824388179 | bayes_pls_golite062009 |
| protein binding | 1.95763087285706 | bayes_pls_golite062009 |
| signal transducer activity | 1.51882027675546 | bayes_pls_golite062009 |
| molecular transducer activity | 1.51882027675546 | bayes_pls_golite062009 |
| GTPase regulator activity | 1.50594272418871 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 1.48917924547615 | bayes_pls_golite062009 |
| actin binding | 1.27269944962803 | bayes_pls_golite062009 |
| enzyme regulator activity | 1.13267118951633 | bayes_pls_golite062009 |
| small GTPase regulator activity | 1.10613306581585 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.972529924049714 | bayes_pls_golite062009 |
| protein domain specific binding | 0.650240628628722 | bayes_pls_golite062009 |
| guanyl-nucleotide exchange factor activity | 0.578612934164552 | bayes_pls_golite062009 |
| small GTPase binding | 0.435164744647801 | bayes_pls_golite062009 |
| GTPase binding | 0.423323808323435 | bayes_pls_golite062009 |
| receptor binding | 0.391425518916624 | bayes_pls_golite062009 |
| receptor activity | 0.361604826111032 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.215248461701419 | bayes_pls_golite062009 |
| actin filament binding | 2.21224577798385E-4 | bayes_pls_golite062009 |
