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Protein Overview: YFF4_YEAST

General Information:
Name(s) found: YFF4_YEAST [Swiss-Prot]
Description(s) found:
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  • Uncharacterized membrane protein YFL054C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YFL054C PE=1 SV=1 [Swiss-Prot]
  • Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the presence of ethanol [Saccharomyces cerevisiae] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 646 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYESGRSSS SSESTRPPTL KEEPNGKIAW EESVKKSREN NENDSTLLRR KLGETRKAIE  60
   61 TGGSSRNKLS ALTPLKKVVD ERKDSVQPQV PSMGFTYSLP NLKTLNSFSD AEQARIMQDY 120
  121 LSRGVNQGNS NNYVDPLYRQ LNPTMGSSRN RPVWSLNQPL PHVLDRGLAA KMIQKNMDAR 180
  181 SRASSRRGST DISRGGSTTS VKDWKRLLRG AAPGKKLGDI EAQTQRDNTV GADVKPTKLE 240
  241 PENPQKPSNT HIENVSRKKK RTSHNVNFSL GDESYASSIA DAESRKLKNM QTLDGSTPVY 300
  301 TKLPEELIEE ENKSTSALDG NEIGASEDED ADIMTFPNFW AKIRYHMREP FAEFLGTLVL 360
  361 VIFGVGGNLQ ATVTKGSGGS YESLSFAWGF GCMLGVYVAG GISGGHINPA VTISMAIFRK 420
  421 FPWKKVPVYI VAQIIGAYFG GAMAYGYFWS SITEFEGGPH IRTTATGACL FTDPKSYVTW 480
  481 RNAFFDEFIG ASILVGCLMA LLDDSNAPPG NGMTALIIGF LVAAIGMALG YQTSFTINPA 540
  541 RDLGPRIFAS MIGYGPHAFH LTHWWWTWGA WGGPIAGGIA GALIYDIFIF TGCESPVNYP 600
  601 DNGYIENRVG KLLHAEFHQN DGTVSDESGV NSNSNTGSKK SVPTSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..236] MSA 2.004996 View MSA. No confident structure predictions are available.
    2 View Details [237..326] deduced N/A No confident structure predictions are available.
    3 View Details [327..460] PSI-BLAST 496.70927 Glycerol uptake facilitator protein GlpF
    4 View Details [461..646] PSI-BLAST 496.70927 Glycerol uptake facilitator protein GlpF

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • water transmembrane transporter activity
    		•  10.0147296433934 bayes_pls_golite062009
  • water channel activity
    		•  9.90182460707078 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  6.84984722645819 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  6.65010837320829 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  6.65010837320829 bayes_pls_golite062009
  • transporter activity
    		•  5.23077472964938 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  5.0695479460357 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  5.06520190871345 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  5.06054430984045 bayes_pls_golite062009
  • channel activity
    		•  5.06054430984045 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  4.83314424546299 bayes_pls_golite062009
  • glycerol channel activity
    		•  4.20153412116491 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.82456291801633 bayes_pls_golite062009
  • pyrimidine transmembrane transporter activity
    		•  2.16047489562591 bayes_pls_golite062009
  • purine transmembrane transporter activity
    		•  1.87440278697248 bayes_pls_golite062009
  • nucleobase transmembrane transporter activity
    		•  1.87440278697248 bayes_pls_golite062009
  • binding
    		•  0.629257163572322 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.516648340085278 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.315342449421593 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.141210715822635 bayes_pls_golite062009
  • urea channel activity
    		•  0.104970224967194 bayes_pls_golite062009
  • urea transmembrane transporter activity
    		•  0.104970224967194 bayes_pls_golite062009
  • amide transmembrane transporter activity
    		•  0.104970224967194 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.0368961725897963 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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