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Protein Overview: RIM15_YEAST

General Information:
Name(s) found: RIM15_YEAST [Swiss-Prot]
Description(s) found:
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  • Serine/threonine-protein kinase RIM15 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RIM15 PE=1 SV=1 [Swiss-Prot]
  • Glucose-repressible protein kinase involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; substrate of Pho80p-Pho85p kinase [Saccharomyces cerevisiae] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1770 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFNRSNTAGG SQAMKEGLGI NKLSPISSNS NPSSLTSSNY EKYLQLATEK NPCMILELEL  60
   61 DGKVRYGSPQ WNTITGVADD SGSSPTYIAD LILGSDQDKG VFQKATDMLL MNDDTSCTIT 120
  121 FKIKAADYEG SAGCDDESTI TTLEARGILI RDGHTQLPSH TMWIVKPRTN DWSDFYANED 180
  181 AQDDMVIQLS DNCDDIDIQL PEEFAKTLGF GAKIFVQYLK RIRLEMIIDE FNLPLPKMEL 240
  241 CRVCENFVPV WWLETHSQSC VCEHRTESLI QLLHDNLLEQ QAILANFTKD SEYKGSQIQV 300
  301 RSNNFLNQVL DSLRELCQDA IDINPSEMVP DLYHSLSTFP QDNGNNNNNN NNNNNNNNAL 360
  361 LDQFPIQKDT VSLNSYFQFS PRTNHNIQNV TSWQSRFFLN DDQDPGLALL IHDTLDLARK 420
  421 KVDAVLRLDN AMTYSLKIKN EVNNYVVQLI REQIEINKHA ILTHPMNLRS SSIFHSPLPQ 480
  481 IHSQQPEAEN LIYSSSTPLQ VQHDQCASFE APSKSHLEPI PFPVSSIEET PTANDIRHPS 540
  541 PLPRSCSNTV MKLPTPRRKL DSNGLFSDAY LNADIIPNPS IESTISIDRD NNTNSRGSSM 600
  601 KQYGIGEATD SRTSNSERPS SSSSRLGIRS RSITPRQKIE YSHVDNDDRT NEMLSRDKDS 660
  661 LQPQPSVDTT ITSSTQATTT GTKTNSNNST NSVLPKLMTS ISLTPRRGSP SFGNLASHSM 720
  721 QQTNSFKLIH DKSPISSPFT FSKDFLTPEQ HPSNIARTDS INNAMLTSPN MPLSPLLLAT 780
  781 NQTVKSPTPS IKDYDILKPI SKGAYGSVYL ARKKLTGDYF AIKVLRKSDM IAKNQVTNVK 840
  841 SERAIMMVQS DKPYVARLFA SFQNKDNLFL VMEYLPGGDL ATLIKMMGYL PDQWAKQYLT 900
  901 EIVVGVNDMH QNGIIHHDLK PENLLIDNAG HVKLTDFGLS RAGLIRRHKF VPHKSSLSIS 960
  961 STLPIDNPAN NFTMNNNNSN HSQLSTPDSF TSDHKQYNRS KKSSLGQQYE HSEYSSTSNS1020
 1021 HSMTPTPSTN TVVYPSYYRG KDRSHGSSNI DLPASLRRSE SQLSFSLLDI SRSSTPPLAN1080
 1081 PTNSNANNIM RRKSLTENKS FSNDLLSSDA IAATNTNINS NNNISLSPAP SDLALFYPDD1140
 1141 SKQNKKFFGT PDYLAPETIE GKGEDNKQCD WWSVGCIFFE LLLGYPPFHA ETPDAVFKKI1200
 1201 LSGVIQWPEF KNEEEEREFL TPEAKDLIEK LLVVDPAKRL GAKGIQEIKD HPYFKNVDWD1260
 1261 HVYDEEASFV PTIDNPEDTD YFDLRGAELQ DFGDDIENDN ANILFGKHGI NTDVSELSAA1320
 1321 NLSPPLNHKN ILSRKLSMSN TTNRSSNNSN SSVHDFGAHT PVNKLSIASV LESVPQETGY1380
 1381 ITPNGTGTTT TSAKNSPNLK NLSLAIPPHM RDRRSSKLND SQTEFGSFNF RNLSALDKAN1440
 1441 KDAINRLKSE HFSEQPGVHR RTSSASLMGS SSDGSVSTPG SNASNTTSGG KLKIHKPTIS1500
 1501 GSPSTFGTFP KTFLRSDSFS TRSYSPERSI SIDSSTLSRK GSIIGDNQQT TANSSDSPTM1560
 1561 TKFKSPLSPA NTTTVSSYFS RQRVLSKSFS QRTNSSDLSA EESDRLQAIS RVNSLRNRRR1620
 1621 SGRKSSSTSE IGYHMDVLVC EPIPIHRYRV TKDLENLGCT VVSVGAGDEL VSRATSGVSF1680
 1681 DLIMTALKLP KLGAIDIVQL LKQTNGANST TPIVAITNYF QEAATSRVFD DVLEKPVKLD1740
 1741 ELKKLVAKYA LKKSQEDEEH TILSDSDETH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..403] deduced N/A No confident structure predictions are available.
    2 View Details [404..785] ORFEUS 11.24 RBP1
    3 View Details [786..980] PSI-BLAST 166.156545 No description for 1lg3A_ was found.
    4 View Details [981..1036]
    [1050..1067]
    [1273..1340]    		 PSI-BLAST 396.0103 cAMP-dependent PK, catalytic subunit
    5 View Details [1037..1049]
    [1068..1272]    		 PSI-BLAST 396.0103 cAMP-dependent PK, catalytic subunit
    6 View Details [1341..1770] deduced N/A No confident structure predictions are available.
    7 View Details [1323..1597] FFAS03 2.08 Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
    8 View Details [1598..1770] FFAS03 4.68 No description for 2ayxA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  3.0194696248926 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.49476861948897 bayes_pls_golite062009
  • DNA binding
    		•  2.19545186072108 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.12699172468275 bayes_pls_golite062009
  • transcription factor activity
    		•  1.6875078525856 bayes_pls_golite062009
  • protein kinase activity
    		•  1.64278494326255 bayes_pls_golite062009
  • protein binding
    		•  1.60673447924806 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.34369087457971 bayes_pls_golite062009
  • kinase activity
    		•  1.27787411134399 bayes_pls_golite062009
  • transcription factor binding
    		•  1.27388174012263 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.26593567694405 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  0.865848090169615 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.859295384298456 bayes_pls_golite062009
  • transcription activator activity
    		•  0.76752398979286 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.5476536728695 bayes_pls_golite062009
  • transferase activity
    		•  0.534003294436004 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.3832620238984 bayes_pls_golite062009
  • histone acetyltransferase binding
    		•  0.288153410088245 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.092160501773862 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle